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The map label for this gene is apbE [H]

Identifier: 159900443

GI number: 159900443

Start: 4923190

End: 4924089

Strand: Reverse

Name: apbE [H]

Synonym: Haur_3928

Alternate gene names: 159900443

Gene position: 4924089-4923190 (Counterclockwise)

Preceding gene: 159900444

Following gene: 159900442

Centisome position: 77.59

GC content: 55.22

Gene sequence:

>900_bases
ATGCGCGAATTGATCTTTCGGGCAATGGGTTGTGAAGTGGCAGTGCTTAGCGATCAGTCAATCGATTTTGAGGCAGTGCC
ACAATGGTTTGAGGCTTGGGAGCAAACGCTAAGCCGTTTTCGCCCAAATAGCGAATTGATGCGGCTCAATCAGCGGGCTG
GTCGGCCACTGGCAGTCAGCGAAACCCTGTGGGAAGTGCTAGGTTTGGCGCTCGATGCTGCCGCTTGGAGCAAAGGCTTA
GTTGTGCCAACTCTGCTGCCCGCGCTTGTGCACGCTGGCTACGATCGCCCATTTGAATTGTTGAGCAACGCGGTCAACCA
ACCACAGGCTTGGCACTATCAGCCACAAGCATGGCTGGCAATTTCTCGCCGCGATCAAGGTCGTTTGGTGCAACTAGCCC
GTGATACCGCCCTTGATTTGGGTGGTATTGCCAAGGGTTGGGCCGCCGATCGAACTGCTCAGCAATTGGCAACTCAAGCG
GCCTGCTTGGTTGATGTCGGTGGCGATTTGGCAACCGCAGGCCAGCGCCAAGATGGTTTGGCTTGGGCGATCGGTGTGCC
AAACCCACGCACCCAGCAGCGTGAAGCCATGATCTGGTTTGCAACTGGTGGTGTAGCAACCTCAGGTGTTGATTATCGGC
GCTGGCGCAAAGGCGATCGCTGGCAACATCACCTCATCGACCCACGCACTGGCGAACCAAGCACGAGCAATGTTTTGAGT
GCCACGGTGATTGCGCCCAACGCAGTGCAAGCCGAAGTTGCCGCCAAAATTGTGGTGTTGCTGGGCATCGAACATGGCTT
GGCTTGGATTAATCAGCATCCTGCTTTTGCGGCACTGGCCTTTGATCACGCTGGCAAAAGCTATAGCAGCGAACGTTTTA
ATAGTTATCGTTGGGAGTAA

Upstream 100 bases:

>100_bases
GCGTCAAGTTGCACCCGTACCGACCGCCGTGCCAGCGCCAGCGCCAGCCGCTCCCGCTGCACCATCACGCAACACTCGTT
CATCACGTTAAAGGTGCTGT

Downstream 100 bases:

>100_bases
ATTCGATGAGTGCTTCAGAAACTGATAAAGCCGCCCGCCTGGCGGCGATTCGCGCCAAAAATGCTGCCCAAAAAGCCCAA
GCTATTGAGCCAACCGAGCC

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVSETLWEVLGLALDAAAWSKGL
VVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLAISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQA
ACLVDVGGDLATAGQRQDGLAWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLS
ATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE

Sequences:

>Translated_299_residues
MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVSETLWEVLGLALDAAAWSKGL
VVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLAISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQA
ACLVDVGGDLATAGQRQDGLAWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLS
ATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE
>Mature_299_residues
MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVSETLWEVLGLALDAAAWSKGL
VVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLAISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQA
ACLVDVGGDLATAGQRQDGLAWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLS
ATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=285, Percent_Identity=27.3684210526316, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 33041; Mature: 33041

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVS
CHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEHH
ETLWEVLGLALDAAAWSKGLVVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
ISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQAACLVDVGGDLATAGQRQDGL
EECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCHHCCCCCCCCC
AWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLS
EEEEECCCCCCCCCCEEEEEEECCCEECCCCHHHHCCCCCCHHHCCCCCCCCCCCCCCEE
ATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE
EEEECCCHHHHHHHHHHHHEEEHHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MRELIFRAMGCEVAVLSDQSIDFEAVPQWFEAWEQTLSRFRPNSELMRLNQRAGRPLAVS
CHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEHH
ETLWEVLGLALDAAAWSKGLVVPTLLPALVHAGYDRPFELLSNAVNQPQAWHYQPQAWLA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
ISRRDQGRLVQLARDTALDLGGIAKGWAADRTAQQLATQAACLVDVGGDLATAGQRQDGL
EECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCHHCCCCCCCCC
AWAIGVPNPRTQQREAMIWFATGGVATSGVDYRRWRKGDRWQHHLIDPRTGEPSTSNVLS
EEEEECCCCCCCCCCEEEEEEECCCEECCCCHHHHCCCCCCHHHCCCCCCCCCCCCCCEE
ATVIAPNAVQAEVAAKIVVLLGIEHGLAWINQHPAFAALAFDHAGKSYSSERFNSYRWE
EEEECCCHHHHHHHHHHHHEEEHHHHHHHHCCCCCEEEEEEHHCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]