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The map label for this gene is yacO [H]

Identifier: 159900290

GI number: 159900290

Start: 4743619

End: 4744359

Strand: Reverse

Name: yacO [H]

Synonym: Haur_3773

Alternate gene names: 159900290

Gene position: 4744359-4743619 (Counterclockwise)

Preceding gene: 159900297

Following gene: 159900289

Centisome position: 74.75

GC content: 52.09

Gene sequence:

>741_bases
TTGGAATTATTATATGGACGCAATGCTGTTTTAGAGGCGTTACGTGCTAATCGGCGTAAATTGGGTCGCTTGCTGATTGC
CGATGGTATTAAAGAGGGCGAATCGATGCAGGCGATCAATACAATTGCCCGCGAACGCCGAATGCAAGTTGCTAAAGTGC
AGCGTAGTGAGCTTGATAAACGCACGGCTGGGGCAAACCATCAAGGCATTGCCCTCGAATGCGGTGCCTATCCCTATGTC
GAAGTTGACGATATTATTGAGCTAGCCCGTGAGCGTGGCGAACAGCCGCTGATCTTGATTTTCGACCATTTGCAAGACCC
ACAAAATATTGGCACGCTGATGCGCACCGCCGAAATTGTCGGCGCACATGGCATTATTTTCCCCGATCGGCGCTCGGCCA
GCATCACACCAGCAGTGATTAATGCTTCAGCTGGCGCAGTTGAGCATTTGTATGTGGCCCAAATTACCAACATTGCCCAA
ACCATCAAGCACCTGCAAGAGTACAATATTTGGGTGGCGGGAGTTGAAGATGATGAGCGGGCGGTCGATTTTGATAAGGC
CAATTTGCGCGGAGCCTTGGCTTTGGTGATTGGAGCCGAAGGCCCAGGCTTGGCCCGCTTAACCCGCGAACGCTGCGATT
TATTGGTGCGTTTGCCGATGCGCGGTAACGTTGCCTCGCTCAACGCCGCCACTGCTGGCTCGATCATTTTGTATCATGCT
TGGCGAGTACGCGAAAAGTAG

Upstream 100 bases:

>100_bases
TGCTCCTTCGGTTGCTGATCCATGTCATTCCTCCATTGACAGCTTGACGCTATAATAGCGCAAACTGACCAATAACTTAG
CACCGAATAGGATTGATACT

Downstream 100 bases:

>100_bases
AGCATAGATGTAATGGTTCATTCCCTCACCCCCAACCCCTCTCCCACGGCGGCGGGCGAGGGGAGCATTCCTAGAGCGGT
TCCCCCTCGCCTGCTGGGCG

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MELLYGRNAVLEALRANRRKLGRLLIADGIKEGESMQAINTIARERRMQVAKVQRSELDKRTAGANHQGIALECGAYPYV
EVDDIIELARERGEQPLILIFDHLQDPQNIGTLMRTAEIVGAHGIIFPDRRSASITPAVINASAGAVEHLYVAQITNIAQ
TIKHLQEYNIWVAGVEDDERAVDFDKANLRGALALVIGAEGPGLARLTRERCDLLVRLPMRGNVASLNAATAGSIILYHA
WRVREK

Sequences:

>Translated_246_residues
MELLYGRNAVLEALRANRRKLGRLLIADGIKEGESMQAINTIARERRMQVAKVQRSELDKRTAGANHQGIALECGAYPYV
EVDDIIELARERGEQPLILIFDHLQDPQNIGTLMRTAEIVGAHGIIFPDRRSASITPAVINASAGAVEHLYVAQITNIAQ
TIKHLQEYNIWVAGVEDDERAVDFDKANLRGALALVIGAEGPGLARLTRERCDLLVRLPMRGNVASLNAATAGSIILYHA
WRVREK
>Mature_246_residues
MELLYGRNAVLEALRANRRKLGRLLIADGIKEGESMQAINTIARERRMQVAKVQRSELDKRTAGANHQGIALECGAYPYV
EVDDIIELARERGEQPLILIFDHLQDPQNIGTLMRTAEIVGAHGIIFPDRRSASITPAVINASAGAVEHLYVAQITNIAQ
TIKHLQEYNIWVAGVEDDERAVDFDKANLRGALALVIGAEGPGLARLTRERCDLLVRLPMRGNVASLNAATAGSIILYHA
WRVREK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=257, Percent_Identity=29.9610894941634, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790623, Length=243, Percent_Identity=34.156378600823, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788935, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790083, Length=154, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=255, Percent_Identity=27.843137254902, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27160; Mature: 27160

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLYGRNAVLEALRANRRKLGRLLIADGIKEGESMQAINTIARERRMQVAKVQRSELDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAGANHQGIALECGAYPYVEVDDIIELARERGEQPLILIFDHLQDPQNIGTLMRTAEIV
HHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
GAHGIIFPDRRSASITPAVINASAGAVEHLYVAQITNIAQTIKHLQEYNIWVAGVEDDER
CCCCEECCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCH
AVDFDKANLRGALALVIGAEGPGLARLTRERCDLLVRLPMRGNVASLNAATAGSIILYHA
HCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCEEEECCCCCCEEECCCCCCCCEEEEEE
WRVREK
EECCCC
>Mature Secondary Structure
MELLYGRNAVLEALRANRRKLGRLLIADGIKEGESMQAINTIARERRMQVAKVQRSELDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAGANHQGIALECGAYPYVEVDDIIELARERGEQPLILIFDHLQDPQNIGTLMRTAEIV
HHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
GAHGIIFPDRRSASITPAVINASAGAVEHLYVAQITNIAQTIKHLQEYNIWVAGVEDDER
CCCCEECCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCH
AVDFDKANLRGALALVIGAEGPGLARLTRERCDLLVRLPMRGNVASLNAATAGSIILYHA
HCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCEEEECCCCCCEEECCCCCCCCEEEEEE
WRVREK
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]