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The map label for this gene is aatA [H]

Identifier: 159900187

GI number: 159900187

Start: 4614086

End: 4615408

Strand: Direct

Name: aatA [H]

Synonym: Haur_3670

Alternate gene names: 159900187

Gene position: 4614086-4615408 (Clockwise)

Preceding gene: 159900184

Following gene: 159900188

Centisome position: 72.7

GC content: 52.38

Gene sequence:

>1323_bases
ATGACACTGATTGAAACGGTTGATGCCGCTCACTATTTCGAGCCAAAATCACCCGAACTGAGCAGCCAATCGATCTCCGC
AATGGCGCGTGGCATGGTTGGTTCTGAAATTTTGCGAATTGCCGGTAATGTCCGCACGTTGCAAGCCCAAGGCCGCACAG
TCTGTAATTTCACCGTCGGTGATTTTGCGCCTTCCCAGTTCCCAATTCCTGAAGCGTTGCGCGATGCAGCAATTGAATCA
TATAGCGCTGGCCGCACCAATTACCCACCAGCCGAAGGCGTGATGGCCTTGCGCAAAGCGGTGCTCGACCACTACGAACG
CCGTTTGGGGTTGCGCTATCCCTTGGAAAGCATCCAAATTATTTCTGGCGCACGGCCAGGTCTCTACGCAGCCTATGGCG
TATTGATTGATCCAGGTGAAACGGTGGTCTATCCAGTGCCATCGTGGAACAACAATCACTATGCCTATTTGTGTGGCTCC
AAGGCGATTGAAGTGCCAACTCGCCCTGAAGATGGCTTCTTGCCAACCGCCGAACTGCTTGCGCCATTCATCCAAGAAGC
ACGTTTGATCTCGATTAACTCGCCGCTCAATCCAGCAGGCACGATGATCTCGCCTGAGGAATTGCGCAAAATTAGCGAGT
TGATTGTCAATGAAAATAATCGCCGCAAAGAGCTTGGTTTGCGCTTGCTCTATTTGGTTTACGACCAAATTTATTGGGAA
TTGCAGCTTGGTGATATTCGCCACGTTACGCCGGTCGAAGTGATGCCCGAAATGTCAGCCTACACGATTTTCATCGATGG
CATCTCAAAATCGTGGTCGGCAACTGGCTTGCGGGTTGGCTGGGTTGTGGCTCCGCCGCACATCACCGATCGCATCAAGG
CCTTTTTGAATCACGTTGGCGCGTGGGCACCCCACCCAGAGCAAGAAGCCACAGCGCATATTTTGAATTCAATCGATGTG
CTCGACGATTTCTATGCTCATATGCACAATGAAGTTCGCGCTCGCTTGAATTTGATCTACAACGCCGTACAGGAAATGAA
GGCAGCCGGCTTGCCAGTCGATGCAATTGCACCGCAAGGGGCGATTTATCTTTCCACCCAATTCGATTTGGTTGGCAAGA
GCCTTGATGGTGTGCCAATCACCAGTAACGCCCAAATTGGCGATATCTTGCTGGAGCAAGCAGGCGTGGCCTTGGTGCCA
TTCCAAGCCTTCGGCCTGCGCCAAGAAACCGGCTGGATGCGGCTCTCGGTTGGCGCGGTTTCAATCGCCGACGTTGAGCA
ATGCATCCCACGTATGCGAGCAATTTTGGAGCGCGTCAAGTAA

Upstream 100 bases:

>100_bases
ACTTGTCGCTGCTGCTTGACTGATGACATCTGCTATACTTAGGGACGCGAAATCGTCCCGCAAGCCAAACTGTTCCTCAC
AAATACCGAGGAGTGTAGCA

Downstream 100 bases:

>100_bases
CGATGCCAGATCCACGTGGCCTGCGTTTGCTGCTAGCCCGCCATGGTGCGACCGCCTGGAACGAAGCGGGACGCTACCAA
GGTCGTGCTGATGAAGGGCT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVGDFAPSQFPIPEALRDAAIES
YSAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQIISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGS
KAIEVPTRPEDGFLPTAELLAPFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWE
LQLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVGAWAPHPEQEATAHILNSIDV
LDDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQGAIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVP
FQAFGLRQETGWMRLSVGAVSIADVEQCIPRMRAILERVK

Sequences:

>Translated_440_residues
MTLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVGDFAPSQFPIPEALRDAAIES
YSAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQIISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGS
KAIEVPTRPEDGFLPTAELLAPFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWE
LQLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVGAWAPHPEQEATAHILNSIDV
LDDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQGAIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVP
FQAFGLRQETGWMRLSVGAVSIADVEQCIPRMRAILERVK
>Mature_439_residues
TLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVGDFAPSQFPIPEALRDAAIESY
SAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQIISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGSK
AIEVPTRPEDGFLPTAELLAPFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWEL
QLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVGAWAPHPEQEATAHILNSIDVL
DDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQGAIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVPF
QAFGLRQETGWMRLSVGAVSIADVEQCIPRMRAILERVK

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=337, Percent_Identity=22.8486646884273, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI169881279, Length=337, Percent_Identity=22.8486646884273, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI56713254, Length=331, Percent_Identity=22.9607250755287, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI56713256, Length=372, Percent_Identity=22.0430107526882, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4507369, Length=412, Percent_Identity=22.3300970873786, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=344, Percent_Identity=24.4186046511628, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788627, Length=340, Percent_Identity=23.8235294117647, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=313, Percent_Identity=23.3226837060703, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=208, Percent_Identity=24.0384615384615, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=208, Percent_Identity=24.0384615384615, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=402, Percent_Identity=23.3830845771144, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=413, Percent_Identity=23.4866828087167, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573069, Length=209, Percent_Identity=25.8373205741627, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646114, Length=209, Percent_Identity=25.8373205741627, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573067, Length=209, Percent_Identity=25.8373205741627, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573065, Length=209, Percent_Identity=25.8373205741627, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 48525; Mature: 48394

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVG
CCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEC
DFAPSQFPIPEALRDAAIESYSAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQI
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHE
ISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGSKAIEVPTRPEDGFLPTAELL
ECCCCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHH
APFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWE
HHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEE
LQLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVG
EEECCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHC
AWAPHPEQEATAHILNSIDVLDDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
AIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVPFQAFGLRQETGWMRLSVGAV
EEEEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHHCCCCCCCEEEEEECCE
SIADVEQCIPRMRAILERVK
EHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLIETVDAAHYFEPKSPELSSQSISAMARGMVGSEILRIAGNVRTLQAQGRTVCNFTVG
CHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEC
DFAPSQFPIPEALRDAAIESYSAGRTNYPPAEGVMALRKAVLDHYERRLGLRYPLESIQI
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHE
ISGARPGLYAAYGVLIDPGETVVYPVPSWNNNHYAYLCGSKAIEVPTRPEDGFLPTAELL
ECCCCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHH
APFIQEARLISINSPLNPAGTMISPEELRKISELIVNENNRRKELGLRLLYLVYDQIYWE
HHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEE
LQLGDIRHVTPVEVMPEMSAYTIFIDGISKSWSATGLRVGWVVAPPHITDRIKAFLNHVG
EEECCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHC
AWAPHPEQEATAHILNSIDVLDDFYAHMHNEVRARLNLIYNAVQEMKAAGLPVDAIAPQG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
AIYLSTQFDLVGKSLDGVPITSNAQIGDILLEQAGVALVPFQAFGLRQETGWMRLSVGAV
EEEEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEHHHHCCCCCCCEEEEEECCE
SIADVEQCIPRMRAILERVK
EHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]