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The map label for this gene is galK [C]

Identifier: 159900185

GI number: 159900185

Start: 4612075

End: 4613085

Strand: Reverse

Name: galK [C]

Synonym: Haur_3668

Alternate gene names: 159900185

Gene position: 4613085-4612075 (Counterclockwise)

Preceding gene: 159900186

Following gene: 159900183

Centisome position: 72.69

GC content: 51.34

Gene sequence:

>1011_bases
GTGAAATTGTTTAAAGCCAAAGCACCAATGCGGATTGGTTTTTTCGGCGGGGGCACTGATGTTAGCCCATATGCCGAAGA
ACATGGCGGCAAGGTGCTTAATTGTACGATTGATAAATATGTGCGCTGTATGCTCAAGCCGATCGATCAGCCTGGAATTA
CGATTCGCTCACTCGACTTGAGTGCCGTTAGTCGGGCGGTAACTGGGCGTGAATGGGATGGCAAACTTTCGTTGCCCCAA
GCAGTAATCGATGCTCATCCTGAAATCAACGGCGTAGAAATTACCATGTTCAGCGATGTGCCACCAGGTTCAGGCTTAGG
TTCTTCCTCGGCTTTGGTGGTGAGCATGCTCAAATTGCTCGATACTGCCTACCACCTCAAGCTCGATGCCTACGAAATGG
CCGAGTTGGCCTATCGCATCGAACGAGTTGATTTGGGGATTCCAGGTGGTCGCCAAGACCAATATACAGCGGTGTTTGGT
GGCATGGCCGTGCAGCATTTCGGCGGCCCACAGGTGATCATCGAACGCGTTGCGACCAGTGAAGATGCTCTGTTGGAACT
AGAGTCGTGCCTGATTATTGGCTATGTGCGGGATCGTAAGCTGCTGACCCATAATTTGGTGCAAGACCAAGTGCGGCGGG
TGACCGAGGGCGAAACCTTGCGTCTGCACGATGAAACCAAAGCCATGGTTGATGAGGGTGCGAAACTCTTGCGGCGTGGT
CAGATCAAAGAATTTGGCAAACTGCTTCACCATGCTTGGGAAATTAAAAAAGCCTTCTCACCACATATTGCGCCGCCAAT
TGTCAACGAAATTTATGATTTAGCCTTGCGCCAAGGGGCTTGGGGTGGCAAATTATCGGGTGCTGGTGGCGGTGGCTTTA
TGTGTTTCTGTGTGCCATTTAGCAAGCGGCTGCAACTCGAAGCGGCCTTGATTGAAGCAGGCGTGACCGTGCGACCCTTC
TCGTTTACCAAGCAAGGCGTGCATGCTTGGAGTGTTGAAGAAGACGATTAA

Upstream 100 bases:

>100_bases
ATTATATGAAGCGCCATTGCTTGCGATGGCGTTTTGTTGTGCCAATAACTAACCCTCATCGCTATGCCGCTCGGTTCTGG
CATGGCTCAAGGAGTAGCGT

Downstream 100 bases:

>100_bases
TCTTGATCGATCAAAAAACGGCTGAGGTGGTTGCCTCAGCCGTTTTGTTTTATTCGTCGTCTTCGACGAAGTTTTTGTTT
TCGACGCTGGTTTCATCTTC

Product: GHMP kinase

Products: ADP; alpha-D-Galactose 1-phosphate; H+ [C]

Alternate protein names: Sugar Kinase; D-Glycero-D-Manno-Heptose 7-Phosphate Kinase; Capsular Biosynthesis Sugar Kinase; Kinase GHMP Family; Kinase Related Galactokinase And Mevalonate Kinase; Galactokinase And Mevalonate Kinase-Like Protein; Galactokinase/Homoserine Kinase Family Protein; D-Glycero-D-Manno-Heptose 1-Phosphate Kinase; D-Alpha-D-Heptose-7-Phosphate Kinase HddA; WblW Protein; Galactokinase/Mevalonate Kinase; Ghmp Kinase

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDLSAVSRAVTGREWDGKLSLPQ
AVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLLDTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFG
GMAVQHFGGPQVIIERVATSEDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRG
QIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPFSKRLQLEAALIEAGVTVRPF
SFTKQGVHAWSVEEDD

Sequences:

>Translated_336_residues
MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDLSAVSRAVTGREWDGKLSLPQ
AVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLLDTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFG
GMAVQHFGGPQVIIERVATSEDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRG
QIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPFSKRLQLEAALIEAGVTVRPF
SFTKQGVHAWSVEEDD
>Mature_336_residues
MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDLSAVSRAVTGREWDGKLSLPQ
AVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLLDTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFG
GMAVQHFGGPQVIIERVATSEDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRG
QIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPFSKRLQLEAALIEAGVTVRPF
SFTKQGVHAWSVEEDD

Specific function: Galactose metabolism; first step. [C]

COG id: COG2605

COG function: function code R; Predicted kinase related to galactokinase and mevalonate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI71982876, Length=305, Percent_Identity=25.2459016393443, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.6 [C]

Molecular weight: Translated: 36831; Mature: 36831

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDL
CCCCCCCCCEEEEEECCCCCCCCHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCEEEEECH
SAVSRAVTGREWDGKLSLPQAVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLL
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
DTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFGGMAVQHFGGPQVIIERVATS
HHHHHEEECHHHHHHHHHHHHHEEECCCCCCCCCCEEHHCCCHHHHCCCHHHHHHHHHCC
EDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRG
CHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCC
QIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPF
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
SKRLQLEAALIEAGVTVRPFSFTKQGVHAWSVEEDD
CHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MKLFKAKAPMRIGFFGGGTDVSPYAEEHGGKVLNCTIDKYVRCMLKPIDQPGITIRSLDL
CCCCCCCCCEEEEEECCCCCCCCHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCEEEEECH
SAVSRAVTGREWDGKLSLPQAVIDAHPEINGVEITMFSDVPPGSGLGSSSALVVSMLKLL
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
DTAYHLKLDAYEMAELAYRIERVDLGIPGGRQDQYTAVFGGMAVQHFGGPQVIIERVATS
HHHHHEEECHHHHHHHHHHHHHEEECCCCCCCCCCEEHHCCCHHHHCCCHHHHHHHHHCC
EDALLELESCLIIGYVRDRKLLTHNLVQDQVRRVTEGETLRLHDETKAMVDEGAKLLRRG
CHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCC
QIKEFGKLLHHAWEIKKAFSPHIAPPIVNEIYDLALRQGAWGGKLSGAGGGGFMCFCVPF
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
SKRLQLEAALIEAGVTVRPFSFTKQGVHAWSVEEDD
CHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-Galactose [C]

Specific reaction: ATP + D-Galactose <==> ADP + alpha-D-Galactose 1-phosphate + H+ [C]

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA