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The map label for this gene is araD [H]

Identifier: 159900180

GI number: 159900180

Start: 4605664

End: 4606305

Strand: Direct

Name: araD [H]

Synonym: Haur_3663

Alternate gene names: 159900180

Gene position: 4605664-4606305 (Clockwise)

Preceding gene: 159900179

Following gene: 159900181

Centisome position: 72.57

GC content: 49.38

Gene sequence:

>642_bases
ATGTTAGAAACAATTAAACACGAACTCTGGAAATTGCACCTTGAATTGCCCAAAAATGGCTTGGTGACTTGGACTTCGGG
CAACGTCAGTGCCCGTGATCCTGAAACCAATTTGGTGGTAATCAAGCCGAGCGGCGTGATGTTTGAAGATTTGCGCCCAG
CCGATCATGTGGTCGTCGATTTAAACGGCAATGTGATCGAAGGCGACCTAAAACCATCATCGGATACCGCCAGCCATTTG
TATATTTATCGCCATCGCCCTGATGTCAATGGGATTGTGCATACACACTCGCCATTCGCCACGGCTTTTGCGGCTAACGG
CAAATCAATTCCGGTTTATCTCACAGCAATGGCCGATGAATTTGGTGGACCGATTCCATGTGCTGGATTTGCCTTGATTG
GTGGCGAAGAAATTGGCCAGCAGGTGGTTGAACATATCGGCACATCGCCAGCGGTGTTGCTGCAAAATCATGGCGTTTTC
ACAATTGGCAAATCGGCCAAAGCCGCCGTCAAGGCTGCCGTGATGACCGAAGATGTAGCGCGAACGACTTGGTATGCCTT
GCAAATCGGCCAGCCCCAAGAAATCGCTAGCGAAGACGTTGCCAAATTGCACTATCGCTATACCCATGTGTATGGTCAAT
AA

Upstream 100 bases:

>100_bases
AACTACTTTGGTCGTGGCGAAAACGATGTGATGAAGCGCTTGCGAATGCTCCGTCACGCCGCACTCACGGCGTAGTTGCA
GCTAGATTGGAATTGAGACC

Downstream 100 bases:

>100_bases
AGCTGGGGATCGGTTGTTGGGGATCGGGTTATAGATAACTTTGGTTCCCTCACCCCCTAGCCCCCTCTCCCGCCCAGCAG
GCGAGGGGGAAACCCTTGAT

Product: L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVDLNGNVIEGDLKPSSDTASHL
YIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADEFGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVF
TIGKSAKAAVKAAVMTEDVARTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ

Sequences:

>Translated_213_residues
MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVDLNGNVIEGDLKPSSDTASHL
YIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADEFGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVF
TIGKSAKAAVKAAVMTEDVARTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ
>Mature_213_residues
MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVDLNGNVIEGDLKPSSDTASHL
YIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADEFGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVF
TIGKSAKAAVKAAVMTEDVARTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. Probably Involved In A Metabolic Pathway With Sgah And Sgau. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790642, Length=203, Percent_Identity=46.3054187192118, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786247, Length=231, Percent_Identity=41.1255411255411, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790008, Length=231, Percent_Identity=39.3939393939394, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1789164, Length=186, Percent_Identity=34.4086021505376, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1789094, Length=186, Percent_Identity=26.3440860215054, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 23132; Mature: 23132

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVD
CCHHHHHHHEEEEEECCCCCEEEEECCCEECCCCCCCEEEECCCCCEEECCCCCCEEEEE
LNGNVIEGDLKPSSDTASHLYIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADE
ECCCEEECCCCCCCCCCEEEEEEEECCCCCCEEEECCCCEEEEECCCCCCEEEEEEEEHH
FGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVFTIGKSAKAAVKAAVMTEDVA
HCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHH
RTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ
HEEEEEEECCCCHHHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MLETIKHELWKLHLELPKNGLVTWTSGNVSARDPETNLVVIKPSGVMFEDLRPADHVVVD
CCHHHHHHHEEEEEECCCCCEEEEECCCEECCCCCCCEEEECCCCCEEECCCCCCEEEEE
LNGNVIEGDLKPSSDTASHLYIYRHRPDVNGIVHTHSPFATAFAANGKSIPVYLTAMADE
ECCCEEECCCCCCCCCCEEEEEEEECCCCCCEEEECCCCEEEEECCCCCCEEEEEEEEHH
FGGPIPCAGFALIGGEEIGQQVVEHIGTSPAVLLQNHGVFTIGKSAKAAVKAAVMTEDVA
HCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHH
RTTWYALQIGQPQEIASEDVAKLHYRYTHVYGQ
HEEEEEEECCCCHHHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]