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The map label for this gene is aprX [H]

Identifier: 159900104

GI number: 159900104

Start: 4514514

End: 4516313

Strand: Reverse

Name: aprX [H]

Synonym: Haur_3587

Alternate gene names: 159900104

Gene position: 4516313-4514514 (Counterclockwise)

Preceding gene: 159900106

Following gene: 159900089

Centisome position: 71.16

GC content: 53.44

Gene sequence:

>1800_bases
ATGGATAGAGAACATCGCAGAGGATTTTTTCGCAGTTTATTGCTGGCAAGCCTCTTTTTGAGTGCGATTGGCCTTGCACA
GCCTGTTGCAACCACCCAACCGCAATCAATGTTAGTGCAAGGTGCTGCGCTAAGCAACCAAGCTAGGGCAATTCAAGCAG
TTGGCGGCACTGTCGAACGCCAATTTGCCCGCTTTGAAACCAGCGTAGCCCAATTAACCAAACCACAAATTGCTCAACTG
CAAGCGCAAGGCTTGCGGGTTTTTGCCGATCAAGCGGTTGCTAGCTCAGCGCAAGGAGCTGTTGATCAGCCAATTGCTGT
GCAGGCTGGCCCCAAAAGTAGCAACCCTGCGCCATTGCAATATCCATCGATTGTAACCGGCGCTGATGTGGTGCAACGCC
GTGGTATCGATGGACGCGGCGTGACCGTGGCAGTGATCGATTCGGGTTTGCCAGCGATCGAACGACCTGAGCGTTGGCAG
CGCATCGATAACACGACTGCTCGCTACAACCAAGGCAGCCGTTTTTTGATTTATAAAGACATGTTGGCAAGCAACCAAAT
TACGAATAGCAGCGACCCCTACGGCCATGGAACGCATGTATTTGCCACTTTAGCCGATAATCGCGCTTTGCCAGCAGGCT
ATAGCGGAGCCAAAGTCGGGATTGCCCCAGGCGCGAATTATGTGGTCGTTCGGGCCTTAAATTCGCAAGGCCAAGCCTCG
TATAGCACGATTATTGCGGCGATTGATTGGGTGATTGAGCATGCTGACGAGTACGATATTCGGGTGCTGAATCTCTCGTT
GCAAGCCGAAGTGATTGCGCCCTACTGGTATGATCCGCTCAATCAAGCGGTGATGCATGCTTGGAATGAGGGCATCACGG
TGGTGGCAGCGGCTGGCAACACTGGCCCAAATCCTGCCACGATTATGGCTCCAGCCAACGTGCCCTATATCATCAGTGTC
GGGGCAATTCGGCCTGCAATCTACAACGACAATGGCAGCGATAGTTTAGCAGCCTATTCATCGGCTGGGCCAACCGAAAG
TCGTTTTGTTAAGCCCGATGTGGTGATTGCTGGCTCGCGGGTCATTGCACCCCTGCCCGCCGATAGTGTGTTAGCTAATT
CTGGGTCCGCAGGTTTGGTTAGCGAACGCGCCAAACTCGAATGGGCTGATTTGAAAACCTCGCAACAGCTTAATTATTAT
GCCTTGAGTGGCACATCGATGGCCGCCGCCGAAGTCAGTGGAATTGTCGCCTTGTTGTTGCAAGATGAGCCAAATTTGAC
CAATAACCAAATTAAGGCTCGTTTGACTGGCACGGCCCAACTTGCCACTTTGGATGATGGTCAAGCCGCTTACAGCACGT
GGCAACAAGGCGCAGGCAAAGTTGTGCCAACTGCGGTGATCGATGGTAGCAACACTGGCGCTGCCAACGCGGGAATGGAT
TTGCCGACCGACCTGATTGTGAGCAGCAACCCCGATGATACCAGCAACCATTACCAAGGCTCGACTGAGTATGATGCGGT
GACCAACACTTTTACTGATAACACCACGACCTATAGCTCAACCCTTGCGACCAGCTACAGCACCTGGGCGGGGAGCTATA
GTACATGGGCTGGCAGTTATCTAACATGGGCTGGTAGTTACAGCACGTGGGCTGGCAGCTACAGCACGTGGGCTGGCAGT
TACAGCACGTGGGCTGGCAGTTACAGCACGTGGGCTGGCAGTTATAGCACGTGGGCTGGCAATAACGCTGCTGCGAGTGG
AACCACCAATGTCAACGCTGGAAGCCTCGTGAGCGACTAA

Upstream 100 bases:

>100_bases
GGACTAATGGCCATACATAACGTCGAATACTGGCATAGCCTATGATATAGCAGCCTCATTCCGCTCGAAACATCGCATGT
ATGCCAATTTTGGAGGCGCT

Downstream 100 bases:

>100_bases
ATTTCAACCATTTCGAGCGGAGCGTGGGAGCAGCGATGCTTCCACATTTTGGCATCAAAAAAATAGCGCAACAAAACGCT
GGGTTGTGGTTACAACTCAG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVERQFARFETSVAQLTKPQIAQL
QAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQYPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQ
RIDNTTARYNQGSRFLIYKDMLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQAS
YSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGNTGPNPATIMAPANVPYIISV
GAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSRVIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYY
ALSGTSMAAAEVSGIVALLLQDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMD
LPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSYLTWAGSYSTWAGSYSTWAGS
YSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD

Sequences:

>Translated_599_residues
MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVERQFARFETSVAQLTKPQIAQL
QAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQYPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQ
RIDNTTARYNQGSRFLIYKDMLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQAS
YSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGNTGPNPATIMAPANVPYIISV
GAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSRVIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYY
ALSGTSMAAAEVSGIVALLLQDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMD
LPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSYLTWAGSYSTWAGSYSTWAGS
YSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD
>Mature_599_residues
MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVERQFARFETSVAQLTKPQIAQL
QAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQYPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQ
RIDNTTARYNQGSRFLIYKDMLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQAS
YSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGNTGPNPATIMAPANVPYIISV
GAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSRVIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYY
ALSGTSMAAAEVSGIVALLLQDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMD
LPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSYLTWAGSYSTWAGSYSTWAGS
YSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD

Specific function: Displays serine protease activity. Seems to have a broad substrate specificity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 63002; Mature: 63002

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVER
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCHHCCHHHHHHHHCCHHHH
QFARFETSVAQLTKPQIAQLQAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQ
HHHHHHHHHHHHCCCHHHHHHHCCHHEEHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
YPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQRIDNTTARYNQGSRFLIYKD
CCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCHHHCCCCCEEEEEEH
MLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQAS
HHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHH
YSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGN
HHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCC
TGPNPATIMAPANVPYIISVGAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSR
CCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCEEEECCE
VIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYYALSGTSMAAAEVSGIVALLL
EEECCCCCHHHCCCCCCCCCCHHHCEEEHHCCCCCCCEEEEECCCCHHHHHHCCEEEEEE
QDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMD
ECCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
LPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSY
CCCEEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCEEEHHHHHCCHHHCCCCCCCCCCCE
LTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDREHRRGFFRSLLLASLFLSAIGLAQPVATTQPQSMLVQGAALSNQARAIQAVGGTVER
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCHHCCHHHHHHHHCCHHHH
QFARFETSVAQLTKPQIAQLQAQGLRVFADQAVASSAQGAVDQPIAVQAGPKSSNPAPLQ
HHHHHHHHHHHHCCCHHHHHHHCCHHEEHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
YPSIVTGADVVQRRGIDGRGVTVAVIDSGLPAIERPERWQRIDNTTARYNQGSRFLIYKD
CCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHCCCHHHCCCCCEEEEEEH
MLASNQITNSSDPYGHGTHVFATLADNRALPAGYSGAKVGIAPGANYVVVRALNSQGQAS
HHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHH
YSTIIAAIDWVIEHADEYDIRVLNLSLQAEVIAPYWYDPLNQAVMHAWNEGITVVAAAGN
HHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCC
TGPNPATIMAPANVPYIISVGAIRPAIYNDNGSDSLAAYSSAGPTESRFVKPDVVIAGSR
CCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCEEEECCE
VIAPLPADSVLANSGSAGLVSERAKLEWADLKTSQQLNYYALSGTSMAAAEVSGIVALLL
EEECCCCCHHHCCCCCCCCCCHHHCEEEHHCCCCCCCEEEEECCCCHHHHHHCCEEEEEE
QDEPNLTNNQIKARLTGTAQLATLDDGQAAYSTWQQGAGKVVPTAVIDGSNTGAANAGMD
ECCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
LPTDLIVSSNPDDTSNHYQGSTEYDAVTNTFTDNTTTYSSTLATSYSTWAGSYSTWAGSY
CCCEEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCEEEHHHHHCCHHHCCCCCCCCCCCE
LTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGSYSTWAGNNAAASGTTNVNAGSLVSD
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]