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The map label for this gene is nqo9 [H]

Identifier: 159899734

GI number: 159899734

Start: 4066051

End: 4066557

Strand: Reverse

Name: nqo9 [H]

Synonym: Haur_3216

Alternate gene names: 159899734

Gene position: 4066557-4066051 (Counterclockwise)

Preceding gene: 159899735

Following gene: 159899733

Centisome position: 64.07

GC content: 51.48

Gene sequence:

>507_bases
ATGCTGAAAGGAACGATGGCCTATTTTAAGGGTCTCAAAACCACGGCGAAATATCTCTTCAAAAAGCCTGTGACCGTTGA
ATATCCTGAGGTCAAACGGCCTGTCCGCGAGCGCTTCCGTGGTCGGCATGAGCTGAAGCGTTTTGCCAATGGTCTAGAGC
GGTGTATCGGTTGTTCGCTGTGTGCCGCTGCTTGTCCGGCAGATGCAATTTATGTGGTGCCTGGCCAGAATGATCCGGCG
AATCCACGCTCGGCAGGCGAACGCCATGCGGCTGTTTATGAAATTAACATGTTGCGTTGTATTTTCTGTGGCTACTGCGA
AGATGCATGCCCCACCAATGCAATTGTGCTTGAGCATCAGTATGAATTAGCCTTCTACGACCGCCGCGCCTCGATCTATA
CCCAAGATATGTTGCTGGTTGCGGTCGATAAAGGCCACGGCGAAGTGCCACCAGTCTTACAACAAACTGGCAAACAACTT
AACCCACCGGCCCAAATAGACCTGTAG

Upstream 100 bases:

>100_bases
CGACGGCACCGATTCGAATGACATTGCACCGCCGCTTGATGCATAGTGGCGGTTTTGGCGTGAACGCCATAGGAGTCACG
CACCGAGAAAGGAATCGCCA

Downstream 100 bases:

>100_bases
TAAAGGCAAAAGGCAAAAGTCAGAAGGCAAAACCTTTTCAACTATGAGATTTCGGTTTCTAATGCCAAAGCCAAAACTGG
AAGCCACCATTAAGCTTGCA

Product: NADH-quinone oxidoreductase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit 9; NDH-1 subunit 9 [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSLCAAACPADAIYVVPGQNDPA
NPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQYELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQL
NPPAQIDL

Sequences:

>Translated_168_residues
MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSLCAAACPADAIYVVPGQNDPA
NPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQYELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQL
NPPAQIDL
>Mature_168_residues
MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSLCAAACPADAIYVVPGQNDPA
NPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQYELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQL
NPPAQIDL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=146, Percent_Identity=41.7808219178082, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788617, Length=150, Percent_Identity=35.3333333333333, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789075, Length=104, Percent_Identity=38.4615384615385, Blast_Score=68, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555194, Length=146, Percent_Identity=38.3561643835616, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17864306, Length=146, Percent_Identity=39.7260273972603, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18839; Mature: 18839

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSL
CCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
CAAACPADAIYVVPGQNDPANPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEEEC
YELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQLNPPAQIDL
EEEEEECCCHHHEECCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLKGTMAYFKGLKTTAKYLFKKPVTVEYPEVKRPVRERFRGRHELKRFANGLERCIGCSL
CCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
CAAACPADAIYVVPGQNDPANPRSAGERHAAVYEINMLRCIFCGYCEDACPTNAIVLEHQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEEEC
YELAFYDRRASIYTQDMLLVAVDKGHGEVPPVLQQTGKQLNPPAQIDL
EEEEEECCCHHHEECCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]