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The map label for this gene is tynA [H]

Identifier: 159899631

GI number: 159899631

Start: 3926198

End: 3927376

Strand: Reverse

Name: tynA [H]

Synonym: Haur_3112

Alternate gene names: 159899631

Gene position: 3927376-3926198 (Counterclockwise)

Preceding gene: 159899632

Following gene: 159899624

Centisome position: 61.88

GC content: 48.43

Gene sequence:

>1179_bases
ATGAAGCTTTCAGCACGTTGGGGCATGCTGCTCGGGATGCTATTAATTGCGGTCAGTTTGTTTAGCACCCAGACTCAGCA
AGAAGCCAATGCCCAGACCCGCGACCGCTGCTCAGGCGGCAGTTTCGTGATTAATAAAACCTTGGCAAATGGCGCTAATT
GGACATTATGTTGGGAAGAACGTAGCAGCGAAGGCATCGTGTTGCGCGGCATCCGCTATACACCACCAGGTGGTAGCCAA
ATCTCAGTAATCAATCAAATCAATTTGGCCCAAATTCACGTACCCTACGACGATAACACTGCCCGTTTCCATGATCTCTC
GGATTATGGCTTGGGTGGTGGCCATCTCAATAATATGGTGGCAGCAGATTGCCCCGATGGTACCTTGATTCAAAACAACA
GTCGGAATGTGCTGTGTATGACGGTTGTACCAACTGGTTACGCCTACAAATACTATGCCCAAGTCAAACAAGGCTCGGCC
TTGGTATTACGCTCGGTTTCGCATATTGGTGCATATAACTACGTCAGCCAATGGATTTTTCACGACGATGCCACGATTGA
GCCAGGCATCGGCGCGACTGGTAAATTACAAAAATGTACCAATGTCGCCAAATATGGCTGGAAAATCGATGCAAGCAGCT
GCCAATATGGCACATCGCACATTCACAATTACTACTGGCGAATCGATTTTGCCCTCGGTGGCAATACCAATAACGTAGTG
GAGCAAATCGAATTCGATTCGAGCGGTGCTGCTCAGCGTAATCTTCAATTGCAAGATTACACCGCCGAAACCGCAGTTAA
ATTCAGCCCAGAAACCTTCCGCTCATGGCGGGTTAAGAACAAAACGGTTACCAACAGCGACGGTCATGCGATCTCCTATG
AGTTGATCGGCAATTCAGATCATGTATTTCGTGGGCCAACCTTCGAGCCATGGACGAATAACGATGTGTATGTGACCGAA
AATAACCCTTGTGAACGTTGGGTTTCGCACAACGATGGCAGTGGTTGTGCCGATGATGTCAGTGGTTTTGTCAATAACCA
AACCCTAACTGACCCGATCGTTTGGTTTGGAATCACCTTCCATCACTTACCGCGCGACGAAGATGACCCGTTAATGTCAT
CACACTGGAGCAGCTTCCAAATGGTACCACGCGACTTATACGCCAGCCAACAACGCTAA

Upstream 100 bases:

>100_bases
TTGTTGCTCAGCGCCGATAATGAATGGGCGGTCAATAGCACCCCGATTGTCGATCTCTCGAATGGCCTTGTGGTCAGTTT
AAATCGTTAGGAGTTTGGTG

Downstream 100 bases:

>100_bases
AACAACAAACGCCCGCTCAAACTTACTTGAGCGGGCGTTTTTATGGCTATTTGCCAGGGGTTGGTGTAATCGTTGGGGTT
GGCGGTGGCGGTGGGGTTTG

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase; Monamine oxidase; Tyramine oxidase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEERSSEGIVLRGIRYTPPGGSQ
ISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMVAADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSA
LVLRSVSHIGAYNYVSQWIFHDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVV
EQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSDHVFRGPTFEPWTNNDVYVTE
NNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITFHHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR

Sequences:

>Translated_392_residues
MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEERSSEGIVLRGIRYTPPGGSQ
ISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMVAADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSA
LVLRSVSHIGAYNYVSQWIFHDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVV
EQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSDHVFRGPTFEPWTNNDVYVTE
NNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITFHHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR
>Mature_392_residues
MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEERSSEGIVLRGIRYTPPGGSQ
ISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMVAADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSA
LVLRSVSHIGAYNYVSQWIFHDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVV
EQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSDHVFRGPTFEPWTNNDVYVTE
NNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITFHHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR

Specific function: Active on tyramine, tryptamine, beta-phenethylamine and dopamine [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787651, Length=413, Percent_Identity=24.455205811138, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR012854
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF07833 Cu_amine_oxidN1; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.21 [H]

Molecular weight: Translated: 43749; Mature: 43749

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCEEEEEEC
RSSEGIVLRGIRYTPPGGSQISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMV
CCCCCEEEEEEEECCCCCCEEEEEEECCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCE
AADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSALVLRSVSHIGAYNYVSQWIF
EECCCCCCEEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHEE
HDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVV
CCCCEECCCCCCCCCHHHHHHHHHCCEEEECCCCCCCHHHHCEEEEEEEEEECCCCCHHH
EQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSD
HEEECCCCCCCHHCCEEEECCCCEEEEECCHHHHHEEECCCEEECCCCCEEEEEEECCCC
HVFRGPTFEPWTNNDVYVTENNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITF
CEEECCCCCCCCCCCEEEECCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEE
HHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR
EECCCCCCCCHHHHCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKLSARWGMLLGMLLIAVSLFSTQTQQEANAQTRDRCSGGSFVINKTLANGANWTLCWEE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCEEEEEEC
RSSEGIVLRGIRYTPPGGSQISVINQINLAQIHVPYDDNTARFHDLSDYGLGGGHLNNMV
CCCCCEEEEEEEECCCCCCEEEEEEECCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCE
AADCPDGTLIQNNSRNVLCMTVVPTGYAYKYYAQVKQGSALVLRSVSHIGAYNYVSQWIF
EECCCCCCEEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHEE
HDDATIEPGIGATGKLQKCTNVAKYGWKIDASSCQYGTSHIHNYYWRIDFALGGNTNNVV
CCCCEECCCCCCCCCHHHHHHHHHCCEEEECCCCCCCHHHHCEEEEEEEEEECCCCCHHH
EQIEFDSSGAAQRNLQLQDYTAETAVKFSPETFRSWRVKNKTVTNSDGHAISYELIGNSD
HEEECCCCCCCHHCCEEEECCCCEEEEECCHHHHHEEECCCEEECCCCCEEEEEEECCCC
HVFRGPTFEPWTNNDVYVTENNPCERWVSHNDGSGCADDVSGFVNNQTLTDPIVWFGITF
CEEECCCCCCCCCCCEEEECCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEE
HHLPRDEDDPLMSSHWSSFQMVPRDLYASQQR
EECCCCCCCCHHHHCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1556068 [H]