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The map label for this gene is pab [H]

Identifier: 159899508

GI number: 159899508

Start: 3774788

End: 3776542

Strand: Reverse

Name: pab [H]

Synonym: Haur_2989

Alternate gene names: 159899508

Gene position: 3776542-3774788 (Counterclockwise)

Preceding gene: 159899512

Following gene: 159899507

Centisome position: 59.51

GC content: 53.05

Gene sequence:

>1755_bases
GTGAGTGCGATTTATGGGCGTTTTGATTTTGCTGATGCAACTGGTCAGCCCCAAGCGTTGGAGTTTCGTCAACCCTTGGC
AATCTACCAAGCGACGACCAGTGCCGAGGTGCTGCCGACGATTCAAGCCGCTCAGGCGGCGGCGCAAGCTGGAGCGTATG
TAATTGGCTATGTGAGCTACGAGGCAGCAGTCGCCTTTGATTCGGCCTTGCAATCGTATCCACCAGCCGCATTGCCGTTG
GTCTGGTTTGCGGCCTTTGCTGTGCCTCAAGTGGTTGAACCAACAACGCAGCACTACCAGCTCTCGCCGTGGCAACCGAC
GATTAGCCTTGAACACTACCGCCAAGCGATCGCGGCGATTCATGCAGCGATTGCCAGTGGTGAAACCTATCAAGTTAACT
ATACCTTGCGACTACGAGCCACGTTTAACGGCGATCCGTTAGCCTTTTATCATGATTTGCGGGCGGCTCAAGCTGCCAAC
TATTGTGCCTACCTCAATCTTGGCGAGTATCAAATTCTCTCGGCTTCGCCCGAACTCTTTTTCGATTGGCGTGATCAGCG
GTTAACCACCAAGCCAATGAAGGGCACGGCTCCGCGTGGGCGTTGGCCTGAAGAAGATCAACGCTTGGCCCGTCAATTAT
TGGCCTCGGAGAAAAACCGTGCCGAAAATTTGATGATTGTTGATCTGTTGCGCAACGATTTGGGGCGAGTCGCAGCGATT
GGCAGCGTTGGCGTGCCACGTTTATTCGAGCTAGAGCGCTATCGCACCGTTTGGCAACTGACCTCAACTGTTGCCGCCAA
AACCAAGCCGAACACCAGCCTGCTTGATATTCTGCAAGCGCTCTTTCCCTGTGGCTCGATCACTGGTGCTCCCAAAGTCA
AAACCATGGAACTGATTCGCCAGTTCGAGGCTGATCCACGGGCGGTTTATTGTGGGGCGATTGGCATACTGCGGCCTGAT
GGCAGCGCAACCTTTAATGTGGCCATTCGCACCGTATGGATCGACCAACAGCGCCAGCAGGCCGAATATGGCGTGGGCGG
CGGTATTACTTGGGATTCGCAGGCTGACGACGAATATGCTGAAGCCCAACTCAAAGCTCAGTTATTGACCGAGCGCTGGC
CCCAATTTGATCTGATCGAAACGCTGCGTTGGGATGGTCAGCGTTACTGGTTGCTTGAACACCATCTACGACGTTTGCAC
GATTCGGCGGCCTATTTTGGCTTTGCCTACGACCAAAGCGCCGTGCTGAATGCGCTCAATCAGCATAGCTTTGGCCATTC
AACTGCGTTGCGAGTGCGTTTGAACCTCACCCATACAGGTGATATTGCAATTAGTAGCAGCCCGCTAACGCCGACCGCCG
ATGGCCAAAAGGTGAGCTTGGCGGCAACAGCGGTTAACTCCCAGAACCGCTTCCTCTACCACAAAACGACTAACCGCAGA
TTGTACGACGAGTACACCCAACAATCCCCCACAGATTTTGATGTGTTGCTATGGAATGAGCATGGTCAATTGACCGAATT
TACCAGAGGCAACCTCGTGCTTGAACTTGATGGCCAGCGTTGGACTCCCCCAGTCGAAGTTGGCTTATTGGCCGGAACTT
ATCGTGCCGAATTGTTGCAACAACGCGCTATCCAAGAGCGTACTTTAGTCCTAGCCGATCTTTGGGCGGCCAGCAAAATT
TGGCTGATTAATAGCGTTCGTGGCTGGGTATTAGTTGAGTTAGCTACTACAGAAGTTACCATTTCTTGCCAATAA

Upstream 100 bases:

>100_bases
ATCAGAAACCTCGTGGGCTAGAAACCGGTGTGCATGCCGCTAGAGTAGCATATCGTTGCGGGCTATGCCAATTGGCTTTA
TTGTTGGGAGGCAACAATTC

Downstream 100 bases:

>100_bases
CACCCTAGGTACTAGTACTAAAGGTATAGTCAAAAGTGGTATAACGCAATGTGTTATATCACTTTATATTCATATAATCG
CGATGTGTGTGTACATTTGT

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSAIYGRFDFADATGQPQALEFRQPLAIYQATTSAEVLPTIQAAQAAAQAGAYVIGYVSYEAAVAFDSALQSYPPAALPL
VWFAAFAVPQVVEPTTQHYQLSPWQPTISLEHYRQAIAAIHAAIASGETYQVNYTLRLRATFNGDPLAFYHDLRAAQAAN
YCAYLNLGEYQILSASPELFFDWRDQRLTTKPMKGTAPRGRWPEEDQRLARQLLASEKNRAENLMIVDLLRNDLGRVAAI
GSVGVPRLFELERYRTVWQLTSTVAAKTKPNTSLLDILQALFPCGSITGAPKVKTMELIRQFEADPRAVYCGAIGILRPD
GSATFNVAIRTVWIDQQRQQAEYGVGGGITWDSQADDEYAEAQLKAQLLTERWPQFDLIETLRWDGQRYWLLEHHLRRLH
DSAAYFGFAYDQSAVLNALNQHSFGHSTALRVRLNLTHTGDIAISSSPLTPTADGQKVSLAATAVNSQNRFLYHKTTNRR
LYDEYTQQSPTDFDVLLWNEHGQLTEFTRGNLVLELDGQRWTPPVEVGLLAGTYRAELLQQRAIQERTLVLADLWAASKI
WLINSVRGWVLVELATTEVTISCQ

Sequences:

>Translated_584_residues
MSAIYGRFDFADATGQPQALEFRQPLAIYQATTSAEVLPTIQAAQAAAQAGAYVIGYVSYEAAVAFDSALQSYPPAALPL
VWFAAFAVPQVVEPTTQHYQLSPWQPTISLEHYRQAIAAIHAAIASGETYQVNYTLRLRATFNGDPLAFYHDLRAAQAAN
YCAYLNLGEYQILSASPELFFDWRDQRLTTKPMKGTAPRGRWPEEDQRLARQLLASEKNRAENLMIVDLLRNDLGRVAAI
GSVGVPRLFELERYRTVWQLTSTVAAKTKPNTSLLDILQALFPCGSITGAPKVKTMELIRQFEADPRAVYCGAIGILRPD
GSATFNVAIRTVWIDQQRQQAEYGVGGGITWDSQADDEYAEAQLKAQLLTERWPQFDLIETLRWDGQRYWLLEHHLRRLH
DSAAYFGFAYDQSAVLNALNQHSFGHSTALRVRLNLTHTGDIAISSSPLTPTADGQKVSLAATAVNSQNRFLYHKTTNRR
LYDEYTQQSPTDFDVLLWNEHGQLTEFTRGNLVLELDGQRWTPPVEVGLLAGTYRAELLQQRAIQERTLVLADLWAASKI
WLINSVRGWVLVELATTEVTISCQ
>Mature_583_residues
SAIYGRFDFADATGQPQALEFRQPLAIYQATTSAEVLPTIQAAQAAAQAGAYVIGYVSYEAAVAFDSALQSYPPAALPLV
WFAAFAVPQVVEPTTQHYQLSPWQPTISLEHYRQAIAAIHAAIASGETYQVNYTLRLRATFNGDPLAFYHDLRAAQAANY
CAYLNLGEYQILSASPELFFDWRDQRLTTKPMKGTAPRGRWPEEDQRLARQLLASEKNRAENLMIVDLLRNDLGRVAAIG
SVGVPRLFELERYRTVWQLTSTVAAKTKPNTSLLDILQALFPCGSITGAPKVKTMELIRQFEADPRAVYCGAIGILRPDG
SATFNVAIRTVWIDQQRQQAEYGVGGGITWDSQADDEYAEAQLKAQLLTERWPQFDLIETLRWDGQRYWLLEHHLRRLHD
SAAYFGFAYDQSAVLNALNQHSFGHSTALRVRLNLTHTGDIAISSSPLTPTADGQKVSLAATAVNSQNRFLYHKTTNRRL
YDEYTQQSPTDFDVLLWNEHGQLTEFTRGNLVLELDGQRWTPPVEVGLLAGTYRAELLQQRAIQERTLVLADLWAASKIW
LINSVRGWVLVELATTEVTISCQ

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=260, Percent_Identity=43.0769230769231, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787518, Length=290, Percent_Identity=29.3103448275862, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786809, Length=196, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=276, Percent_Identity=35.5072463768116, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324361, Length=277, Percent_Identity=27.4368231046931, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 65388; Mature: 65257

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIYGRFDFADATGQPQALEFRQPLAIYQATTSAEVLPTIQAAQAAAQAGAYVIGYVSY
CCCCCCCEECCCCCCCCCCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEH
EAAVAFDSALQSYPPAALPLVWFAAFAVPQVVEPTTQHYQLSPWQPTISLEHYRQAIAAI
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHH
HAAIASGETYQVNYTLRLRATFNGDPLAFYHDLRAAQAANYCAYLNLGEYQILSASPELF
HHHHHCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHHHCCEEEEEECCCEEEEECCCCEE
FDWRDQRLTTKPMKGTAPRGRWPEEDQRLARQLLASEKNRAENLMIVDLLRNDLGRVAAI
EEECCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHEEEE
GSVGVPRLFELERYRTVWQLTSTVAAKTKPNTSLLDILQALFPCGSITGAPKVKTMELIR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
QFEADPRAVYCGAIGILRPDGSATFNVAIRTVWIDQQRQQAEYGVGGGITWDSQADDEYA
HHCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCCHHHH
EAQLKAQLLTERWPQFDLIETLRWDGQRYWLLEHHLRRLHDSAAYFGFAYDQSAVLNALN
HHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCHHHEEEECCHHHHHHHHH
QHSFGHSTALRVRLNLTHTGDIAISSSPLTPTADGQKVSLAATAVNSQNRFLYHKTTNRR
HCCCCCCEEEEEEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCC
LYDEYTQQSPTDFDVLLWNEHGQLTEFTRGNLVLELDGQRWTPPVEVGLLAGTYRAELLQ
HHHHHHCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCHHEEEECCHHHHHHHH
QRAIQERTLVLADLWAASKIWLINSVRGWVLVELATTEVTISCQ
HHHHHHHHHHEEEHHCCCEEEEEECCCCEEEEEEEEEEEEEEEC
>Mature Secondary Structure 
SAIYGRFDFADATGQPQALEFRQPLAIYQATTSAEVLPTIQAAQAAAQAGAYVIGYVSY
CCCCCCEECCCCCCCCCCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEEH
EAAVAFDSALQSYPPAALPLVWFAAFAVPQVVEPTTQHYQLSPWQPTISLEHYRQAIAAI
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHH
HAAIASGETYQVNYTLRLRATFNGDPLAFYHDLRAAQAANYCAYLNLGEYQILSASPELF
HHHHHCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHHHCCEEEEEECCCEEEEECCCCEE
FDWRDQRLTTKPMKGTAPRGRWPEEDQRLARQLLASEKNRAENLMIVDLLRNDLGRVAAI
EEECCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHEEEE
GSVGVPRLFELERYRTVWQLTSTVAAKTKPNTSLLDILQALFPCGSITGAPKVKTMELIR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
QFEADPRAVYCGAIGILRPDGSATFNVAIRTVWIDQQRQQAEYGVGGGITWDSQADDEYA
HHCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCCHHHH
EAQLKAQLLTERWPQFDLIETLRWDGQRYWLLEHHLRRLHDSAAYFGFAYDQSAVLNALN
HHHHHHHHHHHHCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCHHHEEEECCHHHHHHHHH
QHSFGHSTALRVRLNLTHTGDIAISSSPLTPTADGQKVSLAATAVNSQNRFLYHKTTNRR
HCCCCCCEEEEEEEEEEECCCEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCC
LYDEYTQQSPTDFDVLLWNEHGQLTEFTRGNLVLELDGQRWTPPVEVGLLAGTYRAELLQ
HHHHHHCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCHHEEEECCHHHHHHHH
QRAIQERTLVLADLWAASKIWLINSVRGWVLVELATTEVTISCQ
HHHHHHHHHHEEEHHCCCEEEEEECCCCEEEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]