Click here to switch to the map view.

The map label for this gene is selA [H]

Identifier: 159899484

GI number: 159899484

Start: 3739678

End: 3741018

Strand: Reverse

Name: selA [H]

Synonym: Haur_2965

Alternate gene names: 159899484

Gene position: 3741018-3739678 (Counterclockwise)

Preceding gene: 159899485

Following gene: 159899483

Centisome position: 58.95

GC content: 53.91

Gene sequence:

>1341_bases
TTGAGTTTGCGCAATTTGCCAGCGGTACATGGGCTGATTGGCCTGTTGGCCGAGCGTTTCCCCGAACTGCCTGCTCAATG
GTTGCTTGAGGCCGCCCGAACCAGCCTTGAGCAGGCTCGCCACGCGATTCGTTCTCACGCTGCTGTTCCATCAACTAAAC
AAATTGTGGCTCATGCGGTGGACTTAATTCTCCAACGTCAACAACCACCACTGCGCCACGTGATCAATGCCACAGGCGTG
ATTTTACACACCAATCTTGGGCGTGCACCGCTCAGTGCTGCTGCCCATCAGGCCATAATTACGGCCAGTGCTGGCTATAG
CAACCTCGAATACGATTTGGCGCAAGGCGAGCGTGGTTCACGCAATAGCCTGTTGGAGCCACAACTGCAACGCTTAACCG
GAGCCGAAGCGGCATTAGTGGTCAATAATGCGGCGGCGGCAATGTTGCTTTGCTTGAGTTGTTTTGCCCAAGGGCAGGAA
GTAATTGTGAGTCGTGGCCATGCGGTTGAAATTGGCGGCGGCTTTCGAATTCCTGATATTTTGCGCCAAAGTGGTTGCAT
TTTAGTCGATGTTGGCACGACCAATCGCAGCTATTTGCCCGATTATACGGCGGCGATCACCAACCAAACCGCAGCGTTAT
TGCATGTCCATGCCTCGAATTTTCAGGTGCTGGGCTTTACCCACGAGCCAAGTGTGGCCGAATTAGCCCAAGCCGCCCAT
GAGCATCAAAAGCTCTTAATTTGCGATCTTGGCAGCGGTGCGTTGTTAGATACCCAGGCCTATGGATTGGTAGCCGAGCC
AACAGTTGCCATGATGGTTCAAGCCAAGGCTGATTTAGTAGTGTTCAGCGGCGATAAATTGCTTGGTGGCCCGCAAGCAG
GGTTGATTGTCGGCAAACGCCAGCTGATCGATCAACTGCGCAAACATCCATTATTGCGGGCGCTACGAGTTGATAAATTG
ACAATTGCCGCCTTGAGTGCCACGCTTTTGGCCTATGAAACCCAGCGAGCGAGCAGCGAAATTCCAATCTGGCGCATGGT
CACCAGTTCGCTTGATGAATTAGAACAACGCGCACTACCGCTGCTGGCGCAATACCCCGCTGCCGAACTTGTGGCAACTC
ATGCTACCATTGGCGGTGGTTCGCTGCCTGGTTCAAGCTTGCCAAGCCGAGGGCTAGCCCTTGACGGCATGGCTGAAGCT
TTGAGCAAACAACTTCGTGCCAACGACCCACCCATTGTTGGTCGAATTCAAGCGCAGCGCCTAATCCTTGATCTGCGGAC
TGTGCTACCTGAGCAGGATGCAGTGCTTATGGCGGCGTTAGCAGCCCTCGATCCAGCCTAA

Upstream 100 bases:

>100_bases
CCAACCCAAGATCTACCAACCGTGACGAATCCTGGGGTTGAGCCAACTGTGGTTTATCCGTTGCCACGGCCTGCGCCGTC
GCCGATCTCCTGAGGTTGGC

Downstream 100 bases:

>100_bases
CCTGTCATAGAGAGGGACGCAAGCTATGACTTCAAATCAAACGGCATTGCTGCTGGAAACAGCGGTGGCGGCGTTATATG
CTGGCGACCGTCGCAGCGCC

Product: L-seryl-tRNA(Sec) selenium transferase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAVDLILQRQQPPLRHVINATGV
ILHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGSRNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQE
VIVSRGHAVEIGGGFRIPDILRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAH
EHQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKRQLIDQLRKHPLLRALRVDKL
TIAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALPLLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEA
LSKQLRANDPPIVGRIQAQRLILDLRTVLPEQDAVLMAALAALDPA

Sequences:

>Translated_446_residues
MSLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAVDLILQRQQPPLRHVINATGV
ILHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGSRNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQE
VIVSRGHAVEIGGGFRIPDILRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAH
EHQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKRQLIDQLRKHPLLRALRVDKL
TIAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALPLLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEA
LSKQLRANDPPIVGRIQAQRLILDLRTVLPEQDAVLMAALAALDPA
>Mature_445_residues
SLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAVDLILQRQQPPLRHVINATGVI
LHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGSRNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQEV
IVSRGHAVEIGGGFRIPDILRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAHE
HQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKRQLIDQLRKHPLLRALRVDKLT
IAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALPLLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEAL
SKQLRANDPPIVGRIQAQRLILDLRTVLPEQDAVLMAALAALDPA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=425, Percent_Identity=45.8823529411765, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 47408; Mature: 47277

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAV
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLILQRQQPPLRHVINATGVILHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGS
HHHHHCCCCHHHHHHCCCCEEEECCCCCCCHHHHHHHEEEEECCCCCCCEEEHHCCCCCC
RNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQEVIVSRGHAVEIGGGFRIPDI
CCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHH
LRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAH
HHHCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHH
EHQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKR
HCCEEEEEECCCCCEECCCCCCEEECCHHHHEEECCCCEEEEECCCCCCCCCCCCEECHH
QLIDQLRKHPLLRALRVDKLTIAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALP
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEALSKQLRANDPPIVGRIQAQR
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHH
LILDLRTVLPEQDAVLMAALAALDPA
HHHHHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SLRNLPAVHGLIGLLAERFPELPAQWLLEAARTSLEQARHAIRSHAAVPSTKQIVAHAV
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLILQRQQPPLRHVINATGVILHTNLGRAPLSAAAHQAIITASAGYSNLEYDLAQGERGS
HHHHHCCCCHHHHHHCCCCEEEECCCCCCCHHHHHHHEEEEECCCCCCCEEEHHCCCCCC
RNSLLEPQLQRLTGAEAALVVNNAAAAMLLCLSCFAQGQEVIVSRGHAVEIGGGFRIPDI
CCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHH
LRQSGCILVDVGTTNRSYLPDYTAAITNQTAALLHVHASNFQVLGFTHEPSVAELAQAAH
HHHCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHH
EHQKLLICDLGSGALLDTQAYGLVAEPTVAMMVQAKADLVVFSGDKLLGGPQAGLIVGKR
HCCEEEEEECCCCCEECCCCCCEEECCHHHHEEECCCCEEEEECCCCCCCCCCCCEECHH
QLIDQLRKHPLLRALRVDKLTIAALSATLLAYETQRASSEIPIWRMVTSSLDELEQRALP
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LLAQYPAAELVATHATIGGGSLPGSSLPSRGLALDGMAEALSKQLRANDPPIVGRIQAQR
HHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHH
LILDLRTVLPEQDAVLMAALAALDPA
HHHHHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA