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The map label for this gene is fdhA [H]

Identifier: 159899444

GI number: 159899444

Start: 3697151

End: 3699226

Strand: Reverse

Name: fdhA [H]

Synonym: Haur_2925

Alternate gene names: 159899444

Gene position: 3699226-3697151 (Counterclockwise)

Preceding gene: 159899446

Following gene: 159899439

Centisome position: 58.29

GC content: 51.01

Gene sequence:

>2076_bases
ATGACTGAACAAATTCATTATCGAACCTGCCCGCTCTGTGAGGCAATGTGTGGCTTGGCAATTACGGTCGCCGACAATGC
AGTCAAGCAGATTCGGGGTGATCAGGATGATCCACTCAGCCGTGGGCATATTTGCCCCAAAGGTAGTGCCCTCGGCGATA
TTCACCACGACCCTGATCGCTTGCGCCAGCCACTTCAACGCCGTGCTGATGGCTGGCATCAAATTGGTTGGGATGAGGCT
TTTGATTATGCTGCTACCCAATTAAAACAACTTCAGGCTCGCTACGGCCCCGATGCAATCGCGATTTATCAGGGCAATCC
TTCGGTACATAATCTTGGCACAGCTTTAGGTGCTGGCGCGTTTGTCCGCAGTTTGCGCACCAAAAATCGCTTCTCGGCTA
GCTCGGTCGATCAATTGCCGCATCAGTTGGTGGTGTATCACATGTATGGGCATCAATTAATGTTGCCTGTGCCTGATTTA
GATCGAACTCAGTTTTTGTTGATTTTTGGGGCGAATCCAGCGGTTTCAAATGGGAGCATTATGAGCGCCCCCGATATTAA
ACGCCGTTTGAAGGCGATTCAGCAGCGCGGCGGCCAAATTGTGGTGTTTGACCCCCGCCAAAGCGAAACAGCACAATTAG
CCGATCAACATTATTTTATTCAGCCTGGTAGCGATGGCTTGGTATTGGCAGCGCTGATTCATACGATGCTCAAAGAAGGT
TGGGCTAATCCTGATCGGCTAGCTGGCTTTACCAATGGGCTTGATCAGCTTGAAGCGCTGTTCGCACGATTCAGCCCAGC
AGCAGTCGCTGAGGCAACGGGTGTAGCAGCTGATACAATATTGCAACTAGCCCATGATTTTGCCCATGCCAGTAGCGCTG
TTTGCTATGGCCGAATTGGGGTTTCAATCCAGCAGTTTGGTACACTCAGCCAGTGGTTAATTCAGGTACTGAATATCATT
ACTGGCAACTTGGATCGCGAGGGTGGCTCGATGTTTGCCACGCCAGCCTTCGATACGTTGCCACTGGGCAGTAAAGGTAA
TGTTGGGCGGTGGCATACTCGTGTGCGCCAGTTGCCCGAATTCGCTGGCGAGCTGCCTTCAGTCGCTTTGGCCGAAGAGA
TTTTGACCCCGGGCGAAGGCCAAATTCGAGGATTAATCACCTCGGCGGGCAATCCGGTGCTTTCAACGCCCAATGGTCAA
CAACTTGACCAAGCTTTGGCTGGGCTTGAATTTATGCTCTCAATCGACTTCTATTTGAATGAAACCACTCGCCATGCCCA
CTTGATTTTGCCACCAAGCTCACCCTTGGAGCATGATCATTATGATGTGCTGTTTCACAATTTGGCGATTCGTAACACCG
CTAAATACAGCCCCGCGCTATTCGAGATCGATCAAGCTGCTCGCCACGATTGGCAAATTTTCGGCGAATTAACCCAGCGC
ATGAGCGAAAAAGAGGGGCGCATTTTTCCACCAAAAGCGATGCTTGAGCGTGGATTGCGTTCAGGGCCATATGCGATTCA
ACTCAGCGAATTAGCTCAACAACCGCATGGGATTGACCTTGGGCCATTGCAACCACGCCTGCCTGAACGACTTTTCACTG
AGGATAAACAAATTCAGCTTGTGCCACCAGCAATTGCCCACGATTTGGATCGACTAGCCGAATTGTTGCAACAAGCACCA
AGCAAGCAACTACGCTTGATTAGCCGTCGGCAACTGCGCAGCAACAATTCTTGGATGCACAATAGCCAACGTTTAGTCAA
GGGCGATGATCGTTGTACCCTGCAAATGCACCCAGCCGATGCAGCGCAACGCCAACTGAGCCATGGCCAGCAGGTCAGCA
TCAGTTCACGAGTTGGCACAATCGAGGTGGCGCTTGAAGTCAGTGAGTTAATGATGCCTGGGGTGGTCAGCTTGCCGCAT
GGCTGGGGTCATCGCTATTCTGATACCAAAATTCAAATCGCCCAAGCCCATGCTGGCAGCAGCATCAACGATTTAACCGA
TGATCAAGCGATCGATCCATTAAGTGGCAATGCTGCCTTAAATGGAATAGCAGTCGAGGTGCAAGCAGTTGTGTGA

Upstream 100 bases:

>100_bases
GCTGATACTCTAGCATAGGTTGAGCCATGGCTCATCCCTCGCACGACTGATTTTGCTATGCGATAATGCTGCTAATTGTG
TGACGCAAGGAGGCGTAGCG

Downstream 100 bases:

>100_bases
TTGCTTCTACTCAGAGTTGAATGCCACCATTATTGGCTTTATCTTTGGAAAGTTGGTCGGCGTGGCGGGTAGTTTCAGGC
AATCGATATTTGGTTGTGCA

Product: molydopterin dinucleotide-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MTEQIHYRTCPLCEAMCGLAITVADNAVKQIRGDQDDPLSRGHICPKGSALGDIHHDPDRLRQPLQRRADGWHQIGWDEA
FDYAATQLKQLQARYGPDAIAIYQGNPSVHNLGTALGAGAFVRSLRTKNRFSASSVDQLPHQLVVYHMYGHQLMLPVPDL
DRTQFLLIFGANPAVSNGSIMSAPDIKRRLKAIQQRGGQIVVFDPRQSETAQLADQHYFIQPGSDGLVLAALIHTMLKEG
WANPDRLAGFTNGLDQLEALFARFSPAAVAEATGVAADTILQLAHDFAHASSAVCYGRIGVSIQQFGTLSQWLIQVLNII
TGNLDREGGSMFATPAFDTLPLGSKGNVGRWHTRVRQLPEFAGELPSVALAEEILTPGEGQIRGLITSAGNPVLSTPNGQ
QLDQALAGLEFMLSIDFYLNETTRHAHLILPPSSPLEHDHYDVLFHNLAIRNTAKYSPALFEIDQAARHDWQIFGELTQR
MSEKEGRIFPPKAMLERGLRSGPYAIQLSELAQQPHGIDLGPLQPRLPERLFTEDKQIQLVPPAIAHDLDRLAELLQQAP
SKQLRLISRRQLRSNNSWMHNSQRLVKGDDRCTLQMHPADAAQRQLSHGQQVSISSRVGTIEVALEVSELMMPGVVSLPH
GWGHRYSDTKIQIAQAHAGSSINDLTDDQAIDPLSGNAALNGIAVEVQAVV

Sequences:

>Translated_691_residues
MTEQIHYRTCPLCEAMCGLAITVADNAVKQIRGDQDDPLSRGHICPKGSALGDIHHDPDRLRQPLQRRADGWHQIGWDEA
FDYAATQLKQLQARYGPDAIAIYQGNPSVHNLGTALGAGAFVRSLRTKNRFSASSVDQLPHQLVVYHMYGHQLMLPVPDL
DRTQFLLIFGANPAVSNGSIMSAPDIKRRLKAIQQRGGQIVVFDPRQSETAQLADQHYFIQPGSDGLVLAALIHTMLKEG
WANPDRLAGFTNGLDQLEALFARFSPAAVAEATGVAADTILQLAHDFAHASSAVCYGRIGVSIQQFGTLSQWLIQVLNII
TGNLDREGGSMFATPAFDTLPLGSKGNVGRWHTRVRQLPEFAGELPSVALAEEILTPGEGQIRGLITSAGNPVLSTPNGQ
QLDQALAGLEFMLSIDFYLNETTRHAHLILPPSSPLEHDHYDVLFHNLAIRNTAKYSPALFEIDQAARHDWQIFGELTQR
MSEKEGRIFPPKAMLERGLRSGPYAIQLSELAQQPHGIDLGPLQPRLPERLFTEDKQIQLVPPAIAHDLDRLAELLQQAP
SKQLRLISRRQLRSNNSWMHNSQRLVKGDDRCTLQMHPADAAQRQLSHGQQVSISSRVGTIEVALEVSELMMPGVVSLPH
GWGHRYSDTKIQIAQAHAGSSINDLTDDQAIDPLSGNAALNGIAVEVQAVV
>Mature_690_residues
TEQIHYRTCPLCEAMCGLAITVADNAVKQIRGDQDDPLSRGHICPKGSALGDIHHDPDRLRQPLQRRADGWHQIGWDEAF
DYAATQLKQLQARYGPDAIAIYQGNPSVHNLGTALGAGAFVRSLRTKNRFSASSVDQLPHQLVVYHMYGHQLMLPVPDLD
RTQFLLIFGANPAVSNGSIMSAPDIKRRLKAIQQRGGQIVVFDPRQSETAQLADQHYFIQPGSDGLVLAALIHTMLKEGW
ANPDRLAGFTNGLDQLEALFARFSPAAVAEATGVAADTILQLAHDFAHASSAVCYGRIGVSIQQFGTLSQWLIQVLNIIT
GNLDREGGSMFATPAFDTLPLGSKGNVGRWHTRVRQLPEFAGELPSVALAEEILTPGEGQIRGLITSAGNPVLSTPNGQQ
LDQALAGLEFMLSIDFYLNETTRHAHLILPPSSPLEHDHYDVLFHNLAIRNTAKYSPALFEIDQAARHDWQIFGELTQRM
SEKEGRIFPPKAMLERGLRSGPYAIQLSELAQQPHGIDLGPLQPRLPERLFTEDKQIQLVPPAIAHDLDRLAELLQQAPS
KQLRLISRRQLRSNNSWMHNSQRLVKGDDRCTLQMHPADAAQRQLSHGQQVSISSRVGTIEVALEVSELMMPGVVSLPHG
WGHRYSDTKIQIAQAHAGSSINDLTDDQAIDPLSGNAALNGIAVEVQAVV

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=513, Percent_Identity=26.3157894736842, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1787870, Length=754, Percent_Identity=21.7506631299735, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081797, Length=789, Percent_Identity=22.5602027883397, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI171474008, Length=500, Percent_Identity=23, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI145693196, Length=732, Percent_Identity=22.8142076502732, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI3868720, Length=553, Percent_Identity=22.7848101265823, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788534, Length=372, Percent_Identity=22.5806451612903, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI3868719, Length=267, Percent_Identity=26.2172284644195, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787231, Length=497, Percent_Identity=23.1388329979879, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081994, Length=483, Percent_Identity=21.9461697722567, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 75873; Mature: 75742

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQIHYRTCPLCEAMCGLAITVADNAVKQIRGDQDDPLSRGHICPKGSALGDIHHDPDR
CCCCCCCCCCHHHHHHHCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LRQPLQRRADGWHQIGWDEAFDYAATQLKQLQARYGPDAIAIYQGNPSVHNLGTALGAGA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
FVRSLRTKNRFSASSVDQLPHQLVVYHMYGHQLMLPVPDLDRTQFLLIFGANPAVSNGSI
HHHHHHHHCCCCHHHHHHCHHHEEEEEECCCEEEECCCCCCCCEEEEEECCCCCCCCCCC
MSAPDIKRRLKAIQQRGGQIVVFDPRQSETAQLADQHYFIQPGSDGLVLAALIHTMLKEG
CCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHC
WANPDRLAGFTNGLDQLEALFARFSPAAVAEATGVAADTILQLAHDFAHASSAVCYGRIG
CCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECC
VSIQQFGTLSQWLIQVLNIITGNLDREGGSMFATPAFDTLPLGSKGNVGRWHTRVRQLPE
CCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
FAGELPSVALAEEILTPGEGQIRGLITSAGNPVLSTPNGQQLDQALAGLEFMLSIDFYLN
HHCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHEEEEEEEEEC
ETTRHAHLILPPSSPLEHDHYDVLFHNLAIRNTAKYSPALFEIDQAARHDWQIFGELTQR
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MSEKEGRIFPPKAMLERGLRSGPYAIQLSELAQQPHGIDLGPLQPRLPERLFTEDKQIQL
HHHCCCCCCCCHHHHHCCCCCCCCEEEHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEE
VPPAIAHDLDRLAELLQQAPSKQLRLISRRQLRSNNSWMHNSQRLVKGDDRCTLQMHPAD
ECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEEEECCCH
AAQRQLSHGQQVSISSRVGTIEVALEVSELMMPGVVSLPHGWGHRYSDTKIQIAQAHAGS
HHHHHHHCCCEEEECCCCCEEEEEEEHHHHHCCCCEECCCCCCCCCCCCEEEEEECCCCC
SINDLTDDQAIDPLSGNAALNGIAVEVQAVV
CCCCCCCCCCCCCCCCCCEECEEEEEEEEEC
>Mature Secondary Structure 
TEQIHYRTCPLCEAMCGLAITVADNAVKQIRGDQDDPLSRGHICPKGSALGDIHHDPDR
CCCCCCCCCHHHHHHHCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LRQPLQRRADGWHQIGWDEAFDYAATQLKQLQARYGPDAIAIYQGNPSVHNLGTALGAGA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
FVRSLRTKNRFSASSVDQLPHQLVVYHMYGHQLMLPVPDLDRTQFLLIFGANPAVSNGSI
HHHHHHHHCCCCHHHHHHCHHHEEEEEECCCEEEECCCCCCCCEEEEEECCCCCCCCCCC
MSAPDIKRRLKAIQQRGGQIVVFDPRQSETAQLADQHYFIQPGSDGLVLAALIHTMLKEG
CCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHC
WANPDRLAGFTNGLDQLEALFARFSPAAVAEATGVAADTILQLAHDFAHASSAVCYGRIG
CCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECC
VSIQQFGTLSQWLIQVLNIITGNLDREGGSMFATPAFDTLPLGSKGNVGRWHTRVRQLPE
CCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
FAGELPSVALAEEILTPGEGQIRGLITSAGNPVLSTPNGQQLDQALAGLEFMLSIDFYLN
HHCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHEEEEEEEEEC
ETTRHAHLILPPSSPLEHDHYDVLFHNLAIRNTAKYSPALFEIDQAARHDWQIFGELTQR
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MSEKEGRIFPPKAMLERGLRSGPYAIQLSELAQQPHGIDLGPLQPRLPERLFTEDKQIQL
HHHCCCCCCCCHHHHHCCCCCCCCEEEHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCEEE
VPPAIAHDLDRLAELLQQAPSKQLRLISRRQLRSNNSWMHNSQRLVKGDDRCTLQMHPAD
ECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEEEECCCH
AAQRQLSHGQQVSISSRVGTIEVALEVSELMMPGVVSLPHGWGHRYSDTKIQIAQAHAGS
HHHHHHHCCCEEEECCCCCEEEEEEEHHHHHCCCCEECCCCCCCCCCCCEEEEEECCCCC
SINDLTDDQAIDPLSGNAALNGIAVEVQAVV
CCCCCCCCCCCCCCCCCCEECEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]