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The map label for this gene is yfkN [H]

Identifier: 159899425

GI number: 159899425

Start: 3674709

End: 3677327

Strand: Reverse

Name: yfkN [H]

Synonym: Haur_2906

Alternate gene names: 159899425

Gene position: 3677327-3674709 (Counterclockwise)

Preceding gene: 159899428

Following gene: 159899424

Centisome position: 57.94

GC content: 49.1

Gene sequence:

>2619_bases
ATGGCAAAGGTGCCAAACCTCTGTCATCACATGGCTATGACGAAACGAAAACTACTTGTCCTTGTTGCCCTCTGCGCCAT
ATTGAGTGCGCTTGTTCCGCTCAGCTCAACCTTGACCAGTGCCGCGCCAGTTGCTATTGTCGATATTCAATTGTTGAATG
TTTCCGACTGGCACGGGCAACTCGACCCAAGTGGTACACCAGCAGCTGGGGGAGCCTCGACGATCGCAACCTATTGGAAT
GCTGATCGCGCTGCCAACCCCAACACCATTACTTTGACTGCTGGCGATGACTTTGGGGCTACTCCTCCGCTTTCGGGGAT
GTTCGATGAAGTACCCGCTGTGTTGGCCCAACGCATGATGGGTATTCAGGTGAATACCTTTGGCAACCACAACTTCGACC
GTGGGGTTGCTCACTTGCAACAGATGATCGAATTGGCTGGCTCGCCAACCAGTCCATTAACTCCTAGCTCAATCTACAAC
AATGGGATTCCTTTTCACTATGTAGCAGCCAACTTGATCAACACCACTGGCGTGTTGACTGGCGTAGCTCCCTACAAGAT
TTTTGAATTCCAAGGCGTACAAGTTGCGATCATCGGTTTGGTCAACGAAGAAGCTCCAAGCTTGGTGAAGCCAGGCAACT
TCGGGCCAATTCAAATTACCGATTCAGTTGCAGCGGCGATGGCAGCCAAAGCCCAAGCCGAAACTGAAGGCGCTGATGTG
TTTGTGGCAATTACCCACAAAGGGATCACCGCCCCAAATCAAGGCCCATTGATTGATTTTGCCAACGGCGTGACTGGCTT
TGATTTAATCTTAGGCGATCACACCGACTTAAACTTCCAAAATACAATCAACGGGGCATTGGTTACCGAAAACAAGAGCA
AAGGGTTGCAGTATCTTAAGGTTAACTTGACCTACGATACCACAACCGAAACTGTAACCAACAAGAGTGCTACCTTTGTT
ACGCCAACTGCCAATGTGCCTAAAGTTGCTGCGATTGAAGCCATGTTGGCTCCCTATCGGGCACAATTAGCCCAACAATT
TGACACCCCGATTGGTACGACCAGTGGCTTCTACACCCGTGGCAATAACGTCGAACGGGTTGCTGAAGTACCATTGGGCA
ATTTGGTAACCGATGCAATGCGGGTCAAATATGGCACCCAAATTGCCTTTACCAACGGCGGCGGTTTGCGCGACACCTTG
CCATCGTCCTACACGCCAATTAATCGCAACTTGCGCCGTGCGAGCGTCGGCTACCCAACTGGCCCAGGCTATGATTTGGT
GTTAGGCGATATCTATGCGGTCTTGCCATTCGGTAATACGGTGGTAACCCGAACCGTTACTGGTGGTCAATTATGGCAAG
TAATGGAATTTGGCTTGGGCGCGTTGCCTGGGGCAAATGGCCGCTTCCCACAAATTTCGGGCTTCAAAGTAACCTTCGAT
TCATCAAAGCCAATCGGCCAGCAAGTCCAATCGATCACCTTGGATAATGGTACACAGGTGCTTTCAAATACCACCTCGAT
CTATACCCTCGCAACCAACGACTTTACCAACGCTGGTGGCGACGGCTATACCATGCTCAACGATGGCAAAGGCACGACCT
TAGCGGTTATGGCCGATGTGGTGTTGGAATATATCAGCCAAACAACACCAATTATCCCAAGCATCCAAGATCGCTTGCTT
GATGTAACCCGTATCGAGGATATTCACGATCGGATCATTCCAAAGGATGGCACCACTGGGGCCATGAACTTCATGATTAG
CGATCCACGTTTGACGACCGATCCTAATACCACCACCGTAACCTTGACTGGAACTTCATCAAACACTACTTTGGTGCCAA
ATGCCAATATTGTTTTGACTGGTAGTGGTATCAATCGAACAGTAACGGTCACGCCAGTGGCTGGTCGTACAGGCACAGTT
ACCATTCAAATTCGGGTTAATGGTCAAGGCTCAGCCAGTGATACCTTTGTGGTGGTGGTGAACGATAAGCCAACTGCCAA
CAGTGTTGCCAGCCTGACCACCGATGAAGATGCTTCGGTCACGCTTAATATTGGCATAATCGATAGCGACACCAGAGCCA
GCGATATTACAATTACTAGCTTATCGGGTGATCAAGATTTGGTTGCCAATGCTGATATTGTGGAAACTGGCGCAACCAAC
GTTTATACCCGTACCTTCACGATTGCTCCAGTCTTGAATGCTTCGGGTACAACCAACCTGAACTTCTTTATTCAGGATGG
TGTTTCAGCCTATACCCAGACCGTTGCCTTGACCGTCAATGCGGTTAACGATGCACCTGAGCTTTCGGCCTTTATGGATG
AAACGATCAACGTCAATTCAACCCTTGGGCCAATTCTGTTTACCGTGGCCGATATTGATGATGCAGCCGCCAACTTAACC
GTTACCGCTGAATCATCAAACACGATCTTGGTACCAAATGCCAATATTTCAATTGTTGGCACTGGCTCAGAACGTACCTT
GAGCTTGACTCCAGCCGCCAGCCAAACTGGTACAACCACCATTACGGTTACCGTTAATGATGGCGAAGACACCTTCGAAC
GTACCTTTGTGGTAACTGTAGTCAACAACAAGCTTTATCTGCCATTAGTTGGCAAATAA

Upstream 100 bases:

>100_bases
AATTCTAATAGTTGCTCGGTTATTAAGATCGGGTACAATAGATGTGTCAAATCAGCCAACATGCTTAATAAATCATTGTT
GCTCCACGAAAGGGGGATCG

Downstream 100 bases:

>100_bases
CGAACTTAGTAAAACGCGTTACAATACCGCTGAGTGGTTTGCACTCAGCGGTTTGTTTTAATCAAATGGCATAATCATAA
TGAAAAAACAGCTTTTAATT

Product: 5'-nucleotidase domain-containing protein

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 872; Mature: 871

Protein sequence:

>872_residues
MAKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQLDPSGTPAAGGASTIATYWN
ADRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMMGIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYN
NGIPFHYVAANLINTTGVLTGVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADV
FVAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLKVNLTYDTTTETVTNKSATFV
TPTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTRGNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTL
PSSYTPINRNLRRASVGYPTGPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFD
SSKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADVVLEYISQTTPIIPSIQDRLL
DVTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTVTLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTV
TIQIRVNGQGSASDTFVVVVNDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATN
VYTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNSTLGPILFTVADIDDAAANLT
VTAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTTITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK

Sequences:

>Translated_872_residues
MAKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQLDPSGTPAAGGASTIATYWN
ADRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMMGIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYN
NGIPFHYVAANLINTTGVLTGVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADV
FVAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLKVNLTYDTTTETVTNKSATFV
TPTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTRGNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTL
PSSYTPINRNLRRASVGYPTGPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFD
SSKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADVVLEYISQTTPIIPSIQDRLL
DVTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTVTLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTV
TIQIRVNGQGSASDTFVVVVNDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATN
VYTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNSTLGPILFTVADIDDAAANLT
VTAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTTITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK
>Mature_871_residues
AKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQLDPSGTPAAGGASTIATYWNA
DRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMMGIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYNN
GIPFHYVAANLINTTGVLTGVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADVF
VAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLKVNLTYDTTTETVTNKSATFVT
PTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTRGNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTLP
SSYTPINRNLRRASVGYPTGPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFDS
SKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADVVLEYISQTTPIIPSIQDRLLD
VTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTVTLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTVT
IQIRVNGQGSASDTFVVVVNDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATNV
YTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNSTLGPILFTVADIDDAAANLTV
TAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTTITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1786687, Length=593, Percent_Identity=21.4165261382799, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652512, Length=470, Percent_Identity=25.1063829787234, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19921980, Length=470, Percent_Identity=25.1063829787234, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI161076508, Length=470, Percent_Identity=25.1063829787234, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922444, Length=617, Percent_Identity=22.0421393841167, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922446, Length=600, Percent_Identity=22.1666666666667, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24654424, Length=600, Percent_Identity=22.1666666666667, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24641187, Length=572, Percent_Identity=22.7272727272727, Blast_Score=92, Evalue=2e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 91590; Mature: 91459

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
LDPSGTPAAGGASTIATYWNADRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMM
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
GIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYNNGIPFHYVAANLINTTGVLT
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCHHEE
GVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADV
CCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEE
FVAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLK
EEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEEEE
VNLTYDTTTETVTNKSATFVTPTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTR
EEEEECCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
GNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTLPSSYTPINRNLRRASVGYPT
CCCHHHHHHCCCCHHHHHHHHEEECCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCC
GPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFD
CCCCEEEEECEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
SSKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADV
CCCCCCHHHHEEEECCCCEEECCCEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHH
VLEYISQTTPIIPSIQDRLLDVTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEECCCCCEEE
TLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTVTIQIRVNGQGSASDTFVVVV
EEEECCCCCEEECCCCEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCEEEEEE
NDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATN
CCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCEEECCCEEECCCCE
VYTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNS
EEEEEEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCC
TLGPILFTVADIDDAAANLTVTAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTT
CCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCEEEEECCCCCCCCCEE
ITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK
EEEEECCCCCCCEEEEEEEEECCEEEEEECCC
>Mature Secondary Structure 
AKVPNLCHHMAMTKRKLLVLVALCAILSALVPLSSTLTSAAPVAIVDIQLLNVSDWHGQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCC
LDPSGTPAAGGASTIATYWNADRAANPNTITLTAGDDFGATPPLSGMFDEVPAVLAQRMM
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
GIQVNTFGNHNFDRGVAHLQQMIELAGSPTSPLTPSSIYNNGIPFHYVAANLINTTGVLT
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCHHEE
GVAPYKIFEFQGVQVAIIGLVNEEAPSLVKPGNFGPIQITDSVAAAMAAKAQAETEGADV
CCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEE
FVAITHKGITAPNQGPLIDFANGVTGFDLILGDHTDLNFQNTINGALVTENKSKGLQYLK
EEEEEECCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEEEE
VNLTYDTTTETVTNKSATFVTPTANVPKVAAIEAMLAPYRAQLAQQFDTPIGTTSGFYTR
EEEEECCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
GNNVERVAEVPLGNLVTDAMRVKYGTQIAFTNGGGLRDTLPSSYTPINRNLRRASVGYPT
CCCHHHHHHCCCCHHHHHHHHEEECCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCC
GPGYDLVLGDIYAVLPFGNTVVTRTVTGGQLWQVMEFGLGALPGANGRFPQISGFKVTFD
CCCCEEEEECEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
SSKPIGQQVQSITLDNGTQVLSNTTSIYTLATNDFTNAGGDGYTMLNDGKGTTLAVMADV
CCCCCCHHHHEEEECCCCEEECCCEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHH
VLEYISQTTPIIPSIQDRLLDVTRIEDIHDRIIPKDGTTGAMNFMISDPRLTTDPNTTTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEECCCCCEEE
TLTGTSSNTTLVPNANIVLTGSGINRTVTVTPVAGRTGTVTIQIRVNGQGSASDTFVVVV
EEEECCCCCEEECCCCEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCEEEEEE
NDKPTANSVASLTTDEDASVTLNIGIIDSDTRASDITITSLSGDQDLVANADIVETGATN
CCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCEEECCCEEECCCCE
VYTRTFTIAPVLNASGTTNLNFFIQDGVSAYTQTVALTVNAVNDAPELSAFMDETINVNS
EEEEEEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCC
TLGPILFTVADIDDAAANLTVTAESSNTILVPNANISIVGTGSERTLSLTPAASQTGTTT
CCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCEEEEECCCCEEEEECCCCCCCCCEE
ITVTVNDGEDTFERTFVVTVVNNKLYLPLVGK
EEEEECCCCCCCEEEEEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]