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The map label for this gene is gpt [C]

Identifier: 159899406

GI number: 159899406

Start: 3658481

End: 3658987

Strand: Reverse

Name: gpt [C]

Synonym: Haur_2887

Alternate gene names: 159899406

Gene position: 3658987-3658481 (Counterclockwise)

Preceding gene: 159899408

Following gene: 159899405

Centisome position: 57.65

GC content: 46.75

Gene sequence:

>507_bases
ATGAGAGGCCTAATGCGATTCAACGAGGCAGAACGTATGACCATCAAACATGTCCTTTCATGGGATGAAATTCAATCATT
AGTTGAAATTATTAACGAACAATTGCATAATGATTATGATGCCTTGCTCGTTGTTACCCGTGGCGGGATGATTCCAGCCT
GCTTGATTAGCCAACGTCGCAACTGGCGCAATATTCTGGTTGCAGCGGTGCAATTTTACACTGGAATTGGCACAACCCGT
GAAATCCCTACTTTCTTGCAATTCCCCAGTGATCCGCTGATTGTGGGCAAGAAGTTATTGGTAATTGATGATATTTGGGA
TAGTGGCCGCACGATCGCTGCTGTGAAACAACGGCTCGATACTGCGGGAGCCAACTATGAAGTTGCGGTGCTGCACTTCA
AACCAGGTTCATCGAAGGTCGAAGGCAAGCCCGATTTCTTTGCCGCTGAAACTGATCAGTGGATTGTGTATCCGTGGGAA
CCACCCACAGATCCAGATGCAGAATAA

Upstream 100 bases:

>100_bases
CGGTTGAAGAATGTTTCATACTAGCTCCTATCTGGTACAATAGCGCGAATAGCTTAATTGACGGCGCTCATTACCGCCTA
GTTTGGGGAGGTCCCCCACG

Downstream 100 bases:

>100_bases
TGCGAATTGCCATCCTCAGCGATATTCATAGCAATTTAGCTGCTTTCGAGGCTGTACTGGCCGATCTTCAAGGCCAAGCG
GTTGATCACGTCGTCATTAA

Product: phosphoribosyltransferase

Products: Diphosphate; Xanthosine 5'-phosphate [C]

Alternate protein names: Purine Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase; Xanthine/Guanine Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase Conjectural; Phosphoribosyl Transferase Domain-Containing Protein

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRGLMRFNEAERMTIKHVLSWDEIQSLVEIINEQLHNDYDALLVVTRGGMIPACLISQRRNWRNILVAAVQFYTGIGTTR
EIPTFLQFPSDPLIVGKKLLVIDDIWDSGRTIAAVKQRLDTAGANYEVAVLHFKPGSSKVEGKPDFFAAETDQWIVYPWE
PPTDPDAE

Sequences:

>Translated_168_residues
MRGLMRFNEAERMTIKHVLSWDEIQSLVEIINEQLHNDYDALLVVTRGGMIPACLISQRRNWRNILVAAVQFYTGIGTTR
EIPTFLQFPSDPLIVGKKLLVIDDIWDSGRTIAAVKQRLDTAGANYEVAVLHFKPGSSKVEGKPDFFAAETDQWIVYPWE
PPTDPDAE
>Mature_168_residues
MRGLMRFNEAERMTIKHVLSWDEIQSLVEIINEQLHNDYDALLVVTRGGMIPACLISQRRNWRNILVAAVQFYTGIGTTR
EIPTFLQFPSDPLIVGKKLLVIDDIWDSGRTIAAVKQRLDTAGANYEVAVLHFKPGSSKVEGKPDFFAAETDQWIVYPWE
PPTDPDAE

Specific function: Acts On Guanine, Xanthine And To A Lesser Extent Hypoxanthine. [C]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22 [C]

Molecular weight: Translated: 19057; Mature: 19057

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLMRFNEAERMTIKHVLSWDEIQSLVEIINEQLHNDYDALLVVTRGGMIPACLISQRR
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCC
NWRNILVAAVQFYTGIGTTREIPTFLQFPSDPLIVGKKLLVIDDIWDSGRTIAAVKQRLD
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEECCEEEEEECCCCCCCHHHHHHHHHH
TAGANYEVAVLHFKPGSSKVEGKPDFFAAETDQWIVYPWEPPTDPDAE
HCCCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MRGLMRFNEAERMTIKHVLSWDEIQSLVEIINEQLHNDYDALLVVTRGGMIPACLISQRR
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCC
NWRNILVAAVQFYTGIGTTREIPTFLQFPSDPLIVGKKLLVIDDIWDSGRTIAAVKQRLD
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEECCEEEEEECCCCCCCHHHHHHHHHH
TAGANYEVAVLHFKPGSSKVEGKPDFFAAETDQWIVYPWEPPTDPDAE
HCCCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.053 {5-phospho-alpha-D-ribose} 0.02 {xanthine}} [C]

Substrates: 5-Phospho-alpha-D-ribose 1-diphosphate; Xanthine [C]

Specific reaction: 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine --> Diphosphate + Xanthosine 5'-phosphate [C]

General reaction: Glycosyl and Pentosyl group transfer [C]

Inhibitor: 2-Thioxanthine; 6-Thioxanthine; 8-Mercaptoxanthine; ATP; CDP; CTP; GDP; GMP; GTP; TDP; TTP; UDP; UTP; Xanthine; XDP; XMP; XTP [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA