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The map label for this gene is rsbS [H]

Identifier: 159899202

GI number: 159899202

Start: 3441994

End: 3442377

Strand: Direct

Name: rsbS [H]

Synonym: Haur_2683

Alternate gene names: 159899202

Gene position: 3441994-3442377 (Clockwise)

Preceding gene: 159899197

Following gene: 159899203

Centisome position: 54.23

GC content: 47.4

Gene sequence:

>384_bases
TTGGACATCGTTAATATTCCAATTCTTAAGATCGAGAACTTTTTAATTGCTTCGGTTCAGGTTGCCCTGTATGACATGCA
AGCAATTCAGTTCAAAGACGCGGTTCTCCAGAAGATCTATGAGACCAAAGCAAAAGGGGTCATCATCGATCTAACGGCGA
TGGATGTATTAGACAGCTTCGTAGGCCGCTTGATTAGTGATATTGCGGCGATGGCTCGCCTGATGGGGACAACCGTTGTT
ATTACAGGGTTGCAACCTGCCGTCGCAATTACGTTGGTGGAGCTTGGGCTTGAGTTGCCTGGTGTCACAACGGCGCTGAA
TTTGGAAAAAGGCATCGCTAAGTTGCGGCTGATTACGGAGAACAATGCGGATGGCAATGCCTAA

Upstream 100 bases:

>100_bases
CACGCTTGCCGAGTAGCAATATCATACGTATAATAGGCACATACTCCATACGCAAGCTTTTGTTGTGGCTCATCTTCGCG
TTCGACTTCAGGGAGGCCGC

Downstream 100 bases:

>100_bases
TAAAGTCATCACAATTCAGAGCGACCTCGACATTGTGGCGGCACGGATGGCGGCCCGCGATATGGCTAAGGCAATGGGCT
TTGGCGCTATCGACCAAGCA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSFVGRLISDIAAMARLMGTTVV
ITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITENNADGNA

Sequences:

>Translated_127_residues
MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSFVGRLISDIAAMARLMGTTVV
ITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITENNADGNA
>Mature_127_residues
MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSFVGRLISDIAAMARLMGTTVV
ITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITENNADGNA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13624; Mature: 13624

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
VGRLISDIAAMARLMGTTVVITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITE
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHEEEEEEC
NNADGNA
CCCCCCC
>Mature Secondary Structure
MDIVNIPILKIENFLIASVQVALYDMQAIQFKDAVLQKIYETKAKGVIIDLTAMDVLDSF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
VGRLISDIAAMARLMGTTVVITGLQPAVAITLVELGLELPGVTTALNLEKGIAKLRLITE
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHEEEEEEC
NNADGNA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]