Click here to switch to the map view.

The map label for this gene is braD [H]

Identifier: 159899199

GI number: 159899199

Start: 3436927

End: 3438945

Strand: Reverse

Name: braD [H]

Synonym: Haur_2680

Alternate gene names: 159899199

Gene position: 3438945-3436927 (Counterclockwise)

Preceding gene: 159899200

Following gene: 159899198

Centisome position: 54.19

GC content: 52.85

Gene sequence:

>2019_bases
ATGACTGCTTGTGGTAGTGCCCAGTTTTCGTGTAGCCAGCTTTTGCTGCAATTGGTGATTTTTGGCTTGGCCAATGGGGC
AATTATCGCCCTGAATGCGATCAGTGTGACGCTGGTGTATAGCGTTGTGCGCATGCTCAATTTTGCCCATGGCGATTTAT
TTTCCTTGCTCACGGTTTTGGCAGCCGAATCAATCACGATTTTGGGCTTGCAAGTTGGCGCTTCATGGCTCTCGATTGGA
CTAGGATTGCTGGTAGTGCTGGCCATTTGTGCAGTGGTTGGAGCAGGCACAGGCCTGCTCATCGAACAAATTGGCTTTCG
GCCTTTTCGAGGGGCTTCGCGTTTAGCCCCGTTGATGGCGACCCTTGGCATTTCATTTATGCTCTACCAAGCCGCTTTGT
TTGTGCGTACCCTGACCAACGCCGTCATTCCAGGCGAACATCGCAGTGTGCCTGGCATTCCCGAAGTAGCCCGCATTAAT
GTGCCTGATCTGTTGCCGCATGGCAATTTGTTTGGCGATGCGGCGCTAATTTTACAAGGCAAAGATTTGATTGTGCTGGC
GGCGGCAGTGAGTGTGGCGCTAGGCTTGCATTGGCTGTTGCAGCGAACCCGCTTTGGCTGGAAGCTCCAAGCTAGCGCCG
CCGACCCGACCATGGCCCAGTTGTGTGGCATCAACTACAGCGCAACCTTGCGTCAAGTTTTTGCGCTTGGTGGTGCTTTG
GCGGGCTTAGCGGCCTTGCTCTTTAGCCTGTATTACACTGCGCCTTACACCAATTACGGGGCGCAAAGTGGCTTAATTGC
CTTTACTGCTGCATTATTGGGTGGCGTTGGCAGGCCACTGGGAGCATTGTTGAGTGGCTTGGCCTTGGGCATTTTGGCGG
CCTTCAGCGATTATTTTATCGCCGCCCAGTGGACTCCAGCGCTTACGCTTGGTTTGTTGGTGCTGCTGGTGGTGCTGCGC
CAACAACCAAAAATAGAAGATAGCCCGATTAATTCGGCCTTGGTTGGCAGTGTCCAAGCGGTTCGGCAAAACTGGCGTTG
GCTGATTGTGCCAGCATTCTTGGCCTGTGTGCCGTTGCTGAATGCCTGGTTTGAATTGGGTATTCAAGTTGCTGCGATTC
AGATCTTGATTTATGGCTTGCTGGCGTTGGGCTTAAACCTGATTGTTGGCTGGGGCGGCATGCTAGATTTAGGCTATGCT
GCGCCATTTGTATTGGGCGCTTATTTGGTCGGATTAATGAGCACGGGCTTGCATGGCGGTTGGCAAACATGGCTCGCCTC
GGGCGAGTTGGCGGGAATTTTACTGGTTTGTGGGATTGGCGGCAGCCTATTTGGTTGGCTGATTGGGCTTTTAGCAGCAC
GGCTTGATAATGAACTGTTGGCAATTGTTACCTTTGCACTTGGCGTAATTGCACAGCGCGTGTTGCAAAATTGGCGCAGC
CTGACCAATGGCTCAAGCGGCATTTCGGGCGTGCCTAACCTGCAAATTTTTGGCTTAGATTTGGCTACGCCTAGCGCGAC
CTATTATGCAGTGTTAGCAATCACCTGTGGCGTTGGCATCTTGGGCTATAACTTGGTGCGTTCGCATTATGGGCGAGCTT
TGGCGGCCTTGGCCAGCGATGAATTGGCAGCGGCCAGTGTTGGGGTTGCACCTGTGGCGCTCAAACGCTTGGCGTATGCT
TGGGGTGGCGGCGTGGCGGCCTTGGCTGGTGGCCTGTTCGCAGTCAGTTTTAGCTATATCTCGCCGACGTTGGCCGAATT
TCGAGTTTCGGCAATTGCCTTAATTATTGTGGTTTTGGCAGGTTCGCGGCGAATTATTGCCCCGTTGATCGCCACATGTT
TGGTGTTGGGCTACGATTTATTGCTGATTCCCAAGCTTGGTAAATTGTTTGATGATTTACGCGAGCAAACTGGCAATTGG
CTGTGGAGCGCGATTAATCCGCGTGGCGCGAATTTTCTCAGTTTTGGTTTGATGCTCTATTTGACAGTGTGGTATCGCGC
ACGAGCACGCCGCGCATGA

Upstream 100 bases:

>100_bases
GGGTTGGGGGTGAGGGCTAGCGATTATTACCAACCTAAGAAACCATTACAAATAACCCTCTGCTCAACTCCACAATCGCA
CTTTGCTTGGGGGAATCACA

Downstream 100 bases:

>100_bases
GTTGGCCACGGTTTTGGCTAGGCTTGTGGTTGTTTGGGCTAGGCCTAAGTTACAGCAATGTGATTGATCTGCTGAGCGTG
CTGCAACCATGGTTTTTTGC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MTACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVLAAESITILGLQVGASWLSIG
LGLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMATLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARIN
VPDLLPHGNLFGDAALILQGKDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGAL
AGLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFIAAQWTPALTLGLLVLLVVLR
QQPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLLNAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYA
APFVLGAYLVGLMSTGLHGGWQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRS
LTNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASDELAAASVGVAPVALKRLAYA
WGGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLAGSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNW
LWSAINPRGANFLSFGLMLYLTVWYRARARRA

Sequences:

>Translated_672_residues
MTACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVLAAESITILGLQVGASWLSIG
LGLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMATLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARIN
VPDLLPHGNLFGDAALILQGKDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGAL
AGLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFIAAQWTPALTLGLLVLLVVLR
QQPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLLNAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYA
APFVLGAYLVGLMSTGLHGGWQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRS
LTNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASDELAAASVGVAPVALKRLAYA
WGGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLAGSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNW
LWSAINPRGANFLSFGLMLYLTVWYRARARRA
>Mature_671_residues
TACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVLAAESITILGLQVGASWLSIGL
GLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMATLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARINV
PDLLPHGNLFGDAALILQGKDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGALA
GLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFIAAQWTPALTLGLLVLLVVLRQ
QPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLLNAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYAA
PFVLGAYLVGLMSTGLHGGWQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRSL
TNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASDELAAASVGVAPVALKRLAYAW
GGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLAGSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNWL
WSAINPRGANFLSFGLMLYLTVWYRARARRA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=321, Percent_Identity=28.6604361370716, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1789865, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 70576; Mature: 70444

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AAESITILGLQVGASWLSIGLGLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMA
HHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHH
TLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARINVPDLLPHGNLFGDAALILQG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
KDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGAL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
AGLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHE
AAQWTPALTLGLLVLLVVLRQQPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLL
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
NAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYAAPFVLGAYLVGLMSTGLHGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
WQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRS
HHHHHCCCCHHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LTNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASD
HCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAAASVGVAPVALKRLAYAWGGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLA
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHC
GSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNWLWSAINPRGANFLSFGLMLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHH
LTVWYRARARRA
HHHHHHHHHCCC
>Mature Secondary Structure 
TACGSAQFSCSQLLLQLVIFGLANGAIIALNAISVTLVYSVVRMLNFAHGDLFSLLTVL
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AAESITILGLQVGASWLSIGLGLLVVLAICAVVGAGTGLLIEQIGFRPFRGASRLAPLMA
HHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHH
TLGISFMLYQAALFVRTLTNAVIPGEHRSVPGIPEVARINVPDLLPHGNLFGDAALILQG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
KDLIVLAAAVSVALGLHWLLQRTRFGWKLQASAADPTMAQLCGINYSATLRQVFALGGAL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
AGLAALLFSLYYTAPYTNYGAQSGLIAFTAALLGGVGRPLGALLSGLALGILAAFSDYFI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHE
AAQWTPALTLGLLVLLVVLRQQPKIEDSPINSALVGSVQAVRQNWRWLIVPAFLACVPLL
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
NAWFELGIQVAAIQILIYGLLALGLNLIVGWGGMLDLGYAAPFVLGAYLVGLMSTGLHGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
WQTWLASGELAGILLVCGIGGSLFGWLIGLLAARLDNELLAIVTFALGVIAQRVLQNWRS
HHHHHCCCCHHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LTNGSSGISGVPNLQIFGLDLATPSATYYAVLAITCGVGILGYNLVRSHYGRALAALASD
HCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAAASVGVAPVALKRLAYAWGGGVAALAGGLFAVSFSYISPTLAEFRVSAIALIIVVLA
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHC
GSRRIIAPLIATCLVLGYDLLLIPKLGKLFDDLREQTGNWLWSAINPRGANFLSFGLMLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHH
LTVWYRARARRA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]