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The map label for this gene is yccK [H]

Identifier: 159899127

GI number: 159899127

Start: 3348248

End: 3349243

Strand: Direct

Name: yccK [H]

Synonym: Haur_2608

Alternate gene names: 159899127

Gene position: 3348248-3349243 (Clockwise)

Preceding gene: 159899125

Following gene: 159899128

Centisome position: 52.76

GC content: 50.5

Gene sequence:

>996_bases
ATGCAAAAGCGCCAATTAGGCCGTGATGGTTTGGTGGTTTCGGCAGCAGGCTTAGGCTGTATGGCAATGTCGGGGATGTA
CGGGCCTTCGGATCGTGCCGAGAGTATTGCGACAATTCATTCAGCGCTTGATGCTGGAGTCAATTTGCTGGATACTGGCG
ATTTCTATGGGATGGGCCATAACGAACTGCTGATTAGTGAAGCCTTGCGTGAGCGTTCACGCTCCGATGTTGTTTTGAGT
GTCAAATTTGGGGCAATGCGAAGCCCTGATGGTTCGTGGCTCGGCTACGATGCTCGGCCAGCTGCGGTTAAAAATTTCTT
ATACCACAGCCTTACACGCTTGAACACCGATTACATTGATATTTATCGACCTTCGCGGCTTGACCCGAATGTACCGATTG
AAGAAACAATTGGGGCGATTGCCGAGATGGTCGAAAAAGGCTATGTGCGGCATATCGGTTTGTCGGAAGTTGGGGTTGAA
ACGATTCGACGAGCAGCAGCGGTGCATCCAATTGTCGATTTGCAAATTGAATATTCCTTGATGTCGCGTGGTATCGAGGC
CGAAATTTTGCCTGCTTGTCGCGAATTGGGCATCGGCATCACCGCCTATGGAGTGCTTTCGCGTGGCTTGCTAAGCGGTG
CTTGGTCGAAAGAACGGGTTTTGGCTGGCTCAGATTTTCGTTCCCATGGCCCGCGCTTTACTGGCGAGAATCTTGATCAT
AATTTAGAACTGGTTGCAGCCTTGCAAACAATTGCCGAAGCCAAGGGTGCAAGTATTGCCCAAATTGCCAGCGCATGGGT
AGTGGCGCAAGGAGCCGATATTATTCCATTGTTCGGGGCACGCCGCCTACATCAATTGCACGATTCATTGACCAGCCTTG
ACATTAACTTGAATGCTGATGAATTAGGCATAATTGAGCGGGCGATTCCCAAAGGTGCGGCGGCGGGCGAACGCTACAAT
GCCTATCTGATGCAACATTTGGATAGCGAACGCTAA

Upstream 100 bases:

>100_bases
TCAAAATAGCTTACTAAAATGCAATGACAGATATTGACATCTGTCATTTGATAATTTATACTTAAGCCTAGTTACGAATT
TATGCGATGGAGTGATAATC

Downstream 100 bases:

>100_bases
AGCACTTGCGATGCTGCGCTAATCGCTTAAAATGGTGCAAATCGCTTTGCTACAGGAAGACCAACTATGCACGCTGAAAC
GCTGACTCCCGAACGAATTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQKRQLGRDGLVVSAAGLGCMAMSGMYGPSDRAESIATIHSALDAGVNLLDTGDFYGMGHNELLISEALRERSRSDVVLS
VKFGAMRSPDGSWLGYDARPAAVKNFLYHSLTRLNTDYIDIYRPSRLDPNVPIEETIGAIAEMVEKGYVRHIGLSEVGVE
TIRRAAAVHPIVDLQIEYSLMSRGIEAEILPACRELGIGITAYGVLSRGLLSGAWSKERVLAGSDFRSHGPRFTGENLDH
NLELVAALQTIAEAKGASIAQIASAWVVAQGADIIPLFGARRLHQLHDSLTSLDINLNADELGIIERAIPKGAAAGERYN
AYLMQHLDSER

Sequences:

>Translated_331_residues
MQKRQLGRDGLVVSAAGLGCMAMSGMYGPSDRAESIATIHSALDAGVNLLDTGDFYGMGHNELLISEALRERSRSDVVLS
VKFGAMRSPDGSWLGYDARPAAVKNFLYHSLTRLNTDYIDIYRPSRLDPNVPIEETIGAIAEMVEKGYVRHIGLSEVGVE
TIRRAAAVHPIVDLQIEYSLMSRGIEAEILPACRELGIGITAYGVLSRGLLSGAWSKERVLAGSDFRSHGPRFTGENLDH
NLELVAALQTIAEAKGASIAQIASAWVVAQGADIIPLFGARRLHQLHDSLTSLDINLNADELGIIERAIPKGAAAGERYN
AYLMQHLDSER
>Mature_331_residues
MQKRQLGRDGLVVSAAGLGCMAMSGMYGPSDRAESIATIHSALDAGVNLLDTGDFYGMGHNELLISEALRERSRSDVVLS
VKFGAMRSPDGSWLGYDARPAAVKNFLYHSLTRLNTDYIDIYRPSRLDPNVPIEETIGAIAEMVEKGYVRHIGLSEVGVE
TIRRAAAVHPIVDLQIEYSLMSRGIEAEILPACRELGIGITAYGVLSRGLLSGAWSKERVLAGSDFRSHGPRFTGENLDH
NLELVAALQTIAEAKGASIAQIASAWVVAQGADIIPLFGARRLHQLHDSLTSLDINLNADELGIIERAIPKGAAAGERYN
AYLMQHLDSER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=26.2345679012346, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=26.1682242990654, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=26.8518518518519, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=26.8518518518519, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=26.8518518518519, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=27.2435897435897, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI223718702, Length=333, Percent_Identity=27.6276276276276, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI41327764, Length=293, Percent_Identity=27.3037542662116, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=31.5286624203822, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=30.6748466257669, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=27.5757575757576, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=28.9017341040462, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=27.7227722772277, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=322, Percent_Identity=27.0186335403727, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI212645785, Length=299, Percent_Identity=24.0802675585284, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=25.776397515528, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325384, Length=339, Percent_Identity=27.7286135693215, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=25.0825082508251, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=24.633431085044, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=26.171875, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=307, Percent_Identity=24.7557003257329, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24646155, Length=315, Percent_Identity=23.4920634920635, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640980, Length=329, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45549126, Length=329, Percent_Identity=25.531914893617, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35849; Mature: 35849

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRQLGRDGLVVSAAGLGCMAMSGMYGPSDRAESIATIHSALDAGVNLLDTGDFYGMGH
CCCCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NELLISEALRERSRSDVVLSVKFGAMRSPDGSWLGYDARPAAVKNFLYHSLTRLNTDYID
CHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IYRPSRLDPNVPIEETIGAIAEMVEKGYVRHIGLSEVGVETIRRAAAVHPIVDLQIEYSL
EECCCCCCCCCCHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHCCEEEEEEEHHH
MSRGIEAEILPACRELGIGITAYGVLSRGLLSGAWSKERVLAGSDFRSHGPRFTGENLDH
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCCCC
NLELVAALQTIAEAKGASIAQIASAWVVAQGADIIPLFGARRLHQLHDSLTSLDINLNAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEEEEECCCH
ELGIIERAIPKGAAAGERYNAYLMQHLDSER
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKRQLGRDGLVVSAAGLGCMAMSGMYGPSDRAESIATIHSALDAGVNLLDTGDFYGMGH
CCCCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NELLISEALRERSRSDVVLSVKFGAMRSPDGSWLGYDARPAAVKNFLYHSLTRLNTDYID
CHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IYRPSRLDPNVPIEETIGAIAEMVEKGYVRHIGLSEVGVETIRRAAAVHPIVDLQIEYSL
EECCCCCCCCCCHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHCCEEEEEEEHHH
MSRGIEAEILPACRELGIGITAYGVLSRGLLSGAWSKERVLAGSDFRSHGPRFTGENLDH
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCCCC
NLELVAALQTIAEAKGASIAQIASAWVVAQGADIIPLFGARRLHQLHDSLTSLDINLNAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHEEEEECCCH
ELGIIERAIPKGAAAGERYNAYLMQHLDSER
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]