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The map label for this gene is kdpE [H]

Identifier: 159898783

GI number: 159898783

Start: 2895367

End: 2896062

Strand: Direct

Name: kdpE [H]

Synonym: Haur_2262

Alternate gene names: 159898783

Gene position: 2895367-2896062 (Clockwise)

Preceding gene: 159898782

Following gene: 159898786

Centisome position: 45.62

GC content: 50.29

Gene sequence:

>696_bases
ATGGCAACGCAGCCAGTTCGGGTATTACTTGCCGAGGACGAAGATGTTTTACGGGATTTTATTCGGCGGAATCTCCAGGT
GCGTGGGTTTGAGGTGTTGGAAGCAACCAATGGGCTTGAGGCCTTGGCGCTGTGGCATACTGAACAACCCCAATTAATTA
TTTTGGATTTAATGATGCCGCGTTTAACGGGCTTTGAGGTTTGTCAGCGCATTCGCGAGCAATCGATTGTGCCAATTATT
GTGCTAACTGCCTTGGATGCCGAGCGCGATAAAGTTATGGCCTTTGATTTAGGCGCTGATGATTATTTATGTAAACCTTT
TGGGGTCGATGAGTTACTGGCGCGAATTAGGGCAGTCTTGCGACGTAGCCAATGGAGTGTTCAGCCCCAAGCTTCAGGCA
CCAAACGCTATGGCGAGTTGGAGATTGATCTTGAAGCGCATAGCGTTCGGCGAGCAGGCCTCGATGTGCGGTTAACCCCA
ACCGAATTTGCCCTCTTGGCCTATCTGATCACTCATCCCAATAAAGTGCTGACCCATCGCATGCTCTTGCAACACGTGTG
GGGCGATCAATATCGCGATGAAGCTGAATATTTACGGGTCTATATTGGGCGCTTACGCCGCAAACTCGAAGCTGATCCCA
GCAATCCACGCCATTTGCTGACCGAGGCCGGCATTGGCTATCGCTTTGTTAGTTAG

Upstream 100 bases:

>100_bases
AAAACGATCAGGCTGGAACAACGATAGTCTTTCAAATTCCAATCGTGGGCAACGCCGGATAATGCTGATTCGATGATCGC
TTGATGAAGGAGCACTCTGC

Downstream 100 bases:

>100_bases
ATCATGGCTTGGGTTTTCAATATCTCAATCTCGGCTTGGGTATAGCCAAGCTCGTGCAAAATAGCCTGAGTAGCAGCACC
CAAAGCTGGAATACCCTGCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMPRLTGFEVCQRIREQSIVPII
VLTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVLRRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTP
TEFALLAYLITHPNKVLTHRMLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS

Sequences:

>Translated_231_residues
MATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMPRLTGFEVCQRIREQSIVPII
VLTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVLRRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTP
TEFALLAYLITHPNKVLTHRMLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS
>Mature_230_residues
ATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMPRLTGFEVCQRIREQSIVPIIV
LTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVLRRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTPT
EFALLAYLITHPNKVLTHRMLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=46.6367713004484, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.9912663755458, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=35.8078602620087, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.5291479820628, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.1858407079646, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=29.6137339055794, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.4841628959276, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=30.3964757709251, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=27.7533039647577, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=29.0322580645161, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=108, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26614; Mature: 26483

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMP
CCCCCEEEEEECCHHHHHHHHHCCCCCCCCCEEHHCCCCEEEEEEECCCCCEEEEEHHHC
RLTGFEVCQRIREQSIVPIIVLTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVL
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHH
RRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTPTEFALLAYLITHPNKVLTHR
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCEEECHHHHHHHHHHHHCCHHHHHHH
MLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
ATQPVRVLLAEDEDVLRDFIRRNLQVRGFEVLEATNGLEALALWHTEQPQLIILDLMMP
CCCCEEEEEECCHHHHHHHHHCCCCCCCCCEEHHCCCCEEEEEEECCCCCEEEEEHHHC
RLTGFEVCQRIREQSIVPIIVLTALDAERDKVMAFDLGADDYLCKPFGVDELLARIRAVL
CCCHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHH
RRSQWSVQPQASGTKRYGELEIDLEAHSVRRAGLDVRLTPTEFALLAYLITHPNKVLTHR
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCEEECHHHHHHHHHHHHCCHHHHHHH
MLLQHVWGDQYRDEAEYLRVYIGRLRRKLEADPSNPRHLLTEAGIGYRFVS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]