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The map label for this gene is mshA2 [H]

Identifier: 159898770

GI number: 159898770

Start: 2866610

End: 2867881

Strand: Reverse

Name: mshA2 [H]

Synonym: Haur_2249

Alternate gene names: 159898770

Gene position: 2867881-2866610 (Counterclockwise)

Preceding gene: 159898771

Following gene: 159898769

Centisome position: 45.19

GC content: 52.44

Gene sequence:

>1272_bases
GTGCGCCGCGTTGCAATGTTGAGTGTCCATTCGAGTCCTCTAGCTGCTTTGGGTGGTAAAGAAGCTGGTGGTATGAATGT
TTATGTTCGTGAATTAAGCCGTGAGTTGGGTCGCCAAGGGGTGGCGGTCGATATTTATACTCGGTCGCAAGACCCTCACA
CACCGTTGATTACCAATCTTGCGCCAAATGTGCGGGTGTTTGCGGTGCGTGTCGGCCCGGCTGCGCCCTACGATAAGAAT
TGGGTTTTGGATTATTTACCAGAATTTGTCCATCGGATTCGCTGTGTTGCTGATGGCGAAGATATTCATTACGATGTGAT
TCATAGCCATTATTGGCTCTCTGGCGTTGCCGCGCTAGAGTTACGCCAAGCTTGGGGTACACCAGTTATTCATATGTTTC
ACACCTTGGGGGCGATGAAAAATACAATTGCCCGTGGCGATGAAGCTGAAACTGAACAACGAATCGCGATCGAACGCATG
CTGTTGCACGAAGTTGATCGAGTTGTTGCGGCTACGCCGCTTGATCGTGCTCAGATGCTCGAACACTATGACGCTGAGTG
TGAGCGGATTGTGGTTGTGCCGTGTGGGGTTGATGTTGAGCATTTCCACCCGATTGCGCATCAAATTGCCCGCAATGAAT
TAGGCGTGCCGCCGCATCCTCATCGTATGTTGCTGTTTGTCGGGCGGATCGAGCCACTCAAGGGAATTGATACGCTGCTA
CGTTCGATGGCCTTGTTGGCTGAGCAACAGCCCTCGTTACGTGGCGATATTTGTTTGGCGATTATTGGCGGCGATCGGCG
CGAAACCCCAGATCAATGGAGCAGCGAAATGCGGCGTTTGCGGCGTTTGCAGGGCGAATTAGGCATAGGCCATTTGGTCA
CCTTCCAAGGATCGCAAGATCAGCGCAAATTGCCTTTGTTTTATAGTGCTGCCGATATGGTGGTGGTGCCATCGCACTAC
GAATCGTTTGGCATGGTGGCGCTCGAAGCCATGGCCTGTGGCACGCCAGTGATAGCTTCCAACGTTGGTGGTTTGCGCTA
CACCGTGCGTGACGGCGAAACGGGCCTACTGGTGCCGCGCGAAGATCCCGAAGCTTTAGCCGAAAAAATTAGTTTGCTCT
TGAATGATGAGCCTTTGCGTTTACAATTAGGCCGCAACGGCGTGCAAGCAGCCCAACGCTATAGCTGGGCCGCAGTTGCC
CACGATATTCGTGAGTTGTATGATCATGTTGTGTGTGGCGAACCATATGCCGATGTGGTTGGAGCCATGTAG

Upstream 100 bases:

>100_bases
CCTAACTCCTGACCCCTACTCGAAATCGGGCCTAGGATTCAGCAAGCATGGCGCGTTTCGTGGTATGCTGATGATCAGAA
ACCACACACGGGAGGTAGCT

Downstream 100 bases:

>100_bases
CGCCAAGTGTCTACAAAGGAGTGACTATGCCAGTTTTGGCCAAGGCAGCATTGCAGCAAGCATTAGAGCAGCGTTCAGGT
TGGACGGTCGTTGATGGACA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 2; GlcNAc-Ins-P N-acetylglucosaminyltransferase 2 [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNLAPNVRVFAVRVGPAAPYDKN
WVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALELRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERM
LLHEVDRVVAATPLDRAQMLEHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLL
RSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQDQRKLPLFYSAADMVVVPSHY
ESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPREDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVA
HDIRELYDHVVCGEPYADVVGAM

Sequences:

>Translated_423_residues
MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNLAPNVRVFAVRVGPAAPYDKN
WVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALELRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERM
LLHEVDRVVAATPLDRAQMLEHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLL
RSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQDQRKLPLFYSAADMVVVPSHY
ESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPREDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVA
HDIRELYDHVVCGEPYADVVGAM
>Mature_423_residues
MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNLAPNVRVFAVRVGPAAPYDKN
WVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALELRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERM
LLHEVDRVVAATPLDRAQMLEHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLL
RSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQDQRKLPLFYSAADMVVVPSHY
ESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPREDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVA
HDIRELYDHVVCGEPYADVVGAM

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790061, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32564184, Length=232, Percent_Identity=29.7413793103448, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357469, Length=176, Percent_Identity=30.1136363636364, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 47058; Mature: 47058

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNL
CCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCC
APNVRVFAVRVGPAAPYDKNWVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALE
CCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHH
LRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERMLLHEVDRVVAATPLDRAQML
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLL
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH
RSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQD
HHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
QRKLPLFYSAADMVVVPSHYESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPR
CCCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCEEEEEC
EDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVAHDIRELYDHVVCGEPYADVV
CCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAM
CCC
>Mature Secondary Structure
MRRVAMLSVHSSPLAALGGKEAGGMNVYVRELSRELGRQGVAVDIYTRSQDPHTPLITNL
CCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECCC
APNVRVFAVRVGPAAPYDKNWVLDYLPEFVHRIRCVADGEDIHYDVIHSHYWLSGVAALE
CCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHH
LRQAWGTPVIHMFHTLGAMKNTIARGDEAETEQRIAIERMLLHEVDRVVAATPLDRAQML
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EHYDAECERIVVVPCGVDVEHFHPIAHQIARNELGVPPHPHRMLLFVGRIEPLKGIDTLL
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH
RSMALLAEQQPSLRGDICLAIIGGDRRETPDQWSSEMRRLRRLQGELGIGHLVTFQGSQD
HHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
QRKLPLFYSAADMVVVPSHYESFGMVALEAMACGTPVIASNVGGLRYTVRDGETGLLVPR
CCCCCEEEECCCEEEECCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCEEEEEC
EDPEALAEKISLLLNDEPLRLQLGRNGVQAAQRYSWAAVAHDIRELYDHVVCGEPYADVV
CCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAM
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA