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The map label for this gene is yebQ [C]

Identifier: 159898646

GI number: 159898646

Start: 2669021

End: 2670544

Strand: Direct

Name: yebQ [C]

Synonym: Haur_2125

Alternate gene names: 159898646

Gene position: 2669021-2670544 (Clockwise)

Preceding gene: 159898645

Following gene: 159898648

Centisome position: 42.05

GC content: 52.62

Gene sequence:

>1524_bases
ATGACAGAAGCACGTCGCTGGCCATGGGGCTTAATTTGGACAGCCCTGATTATTTTTTTGGCCGCTCTCGACCAAACGGT
GGTGATCACCGTCTTACCAAATGTGGTCAGCACGCTGGGCCTTGATGTTGAGCAAGCGCTTGAACAAGGCATTTGGGTCA
TCACTGGCTATTTGTTGGGCTATACCGTCGCTATGCCCTTGCTAGGACGGATCGCCGATGCCTATGGTCATCGGCGCTTA
TTTTTGGCGGCGCTCGGGGTTTTCGTGGGCGGTTCAATTGGTTGTGCCTTGGCAGATAGCGTTTGGTCGTTGGTGGCATG
GCGCATCGTTCAGGCGATTGGTGGTGGCGCTGTGTTGCCGATCGGTTTGGCAATCTCGATGGATGAAGTTAAGCCAATTC
ATCATGCAACTGCCTTGGGGATTATGGGGGCCGCCGGCGAAGCTGGCGGGGTGCTTGGCCCAGCCTATGGTGGCCTGATT
TCACAAATCCAACTGCTCGATGTTGATGGTTGGCGTTGGGTTTTCTGGCTGAATATTCCACTCGGCGCAGCTTTGGCTTG
GGCAATTATTCGCACCTTACCTGATCGGCCTGGTAATCGCGGGGCGATTGATTATATTGGCGGTGGCTTGATTGCGGTTA
GTTTGACCGCCTTAACTGTGGCGCTTTCACGCTCGCTCGGTAGTTTGGCCATCGAGCCCAGCGCCGAAAGCGGCAACCTC
GATCAATATGCAGTGCAATGGACATCACCATTAACCATTGGCCTGTTGGTGTTGGCAGTGCTCAGTTTTATTGGCTTTAT
CTGGTGGGAACGCCGCACGACAACTCCATTGATCGAGCTAAGCGCCTTCCGCACCCCAGCATTTAGCGCTGCCAATATTA
CCAATGTCTTGGTTGGCATGGCCTTAATTGTGGGCATGGTCAATGTGCCGTTTTTCGTCGGAACAGTGTTGGCAGGCGAT
GCGCTTTCTGGTGGATTAACGTTAATGCGCCTGACCATGATGATCCCGATTGGTGCAGTTTTGGGTGGTATGTTGATGCG
CAAGATTAGTGCGCGGTTGGTTGCTAGCCTCGGCATGATCACCACCGCCGTTGGTTTTGCATTGCTGGGCTTTTGGAAAG
CAGAAACCAATCAATTCCAATTAACCATCTATTTATTGTTAACGGGTACAGGCTTTGGTTTAGTACTCCCCGCCTTGAGT
GCTGCCGCCATTGGCACCGTTGCCCGTGAATCAATGGGCACTGCCGCAGGCTTATTGAATGCATTACGCATGGTCGGAAT
CACCTTGGGTGTTTCGGCTTTGGCTTCATGGAGTTTGGCCTACCGCGCTAGCCTCAATAGTACGTTGGTGTTTACAATGG
AAGATTTCAATACAGGCGCGGCCCAATTGGCCCTAACCCAAAATGAAATGACGGTGTATCACAGCACCTTTTTCGCCGCC
GCAGTAGTTTGCTTAATTGCGTTGATTCCAATTTGGTGGCTGCCACGCGAACGCAGCGAGGGCGACACACCACTGTTTGC
CTAG

Upstream 100 bases:

>100_bases
ATCGCGCCAATCTGTTAACGCCCGTGACAATCCTTGTCGTGGGCTAAAGCTGCATGCTATGATGCAGCACGGAGAGGAAT
TAGCGGTAGGAATCGCAGCT

Downstream 100 bases:

>100_bases
GTTTTAATCGAGCATCCTCGACCCGTTATTGGCGTTGCGCCAATCGCCCAGAGCATGGAACAAAACCACTGACGGGTTGA
GGATAATCAGCACCAAATTT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLGYTVAMPLLGRIADAYGHRRL
FLAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLPIGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLI
SQIQLLDVDGWRWVFWLNIPLGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNL
DQYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGMALIVGMVNVPFFVGTVLAGD
ALSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMITTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALS
AAAIGTVARESMGTAAGLLNALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAA
AVVCLIALIPIWWLPRERSEGDTPLFA

Sequences:

>Translated_507_residues
MTEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLGYTVAMPLLGRIADAYGHRRL
FLAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLPIGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLI
SQIQLLDVDGWRWVFWLNIPLGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNL
DQYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGMALIVGMVNVPFFVGTVLAGD
ALSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMITTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALS
AAAIGTVARESMGTAAGLLNALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAA
AVVCLIALIPIWWLPRERSEGDTPLFA
>Mature_506_residues
TEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLGYTVAMPLLGRIADAYGHRRLF
LAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLPIGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLIS
QIQLLDVDGWRWVFWLNIPLGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNLD
QYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGMALIVGMVNVPFFVGTVLAGDA
LSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMITTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALSA
AAIGTVARESMGTAAGLLNALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAAA
VVCLIALIPIWWLPRERSEGDTPLFA

Specific function: Confers resistance to tetracycline and aminoglycosides such as streptomycin and gentamicin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=436, Percent_Identity=27.2935779816514, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789042, Length=453, Percent_Identity=23.841059602649, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790195, Length=473, Percent_Identity=26.8498942917548, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788710, Length=512, Percent_Identity=22.4609375, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788392, Length=368, Percent_Identity=29.3478260869565, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319770, Length=397, Percent_Identity=23.6775818639798, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=158, Percent_Identity=29.746835443038, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=368, Percent_Identity=23.3695652173913, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53523; Mature: 53392

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLG
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHCCHHHHHHHHHH
YTVAMPLLGRIADAYGHRRLFLAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLISQIQLLDVDGWRWVFWLNIP
EEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHEEEEEECCCEEEEEEEECC
LGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNL
HHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
DQYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
ALIVGMVNVPFFVGTVLAGDALSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALSAAAIGTVARESMGTAAGLLN
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEHHHHHHHH
AVVCLIALIPIWWLPRERSEGDTPLFA
HHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEARRWPWGLIWTALIIFLAALDQTVVITVLPNVVSTLGLDVEQALEQGIWVITGYLLG
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHCCHHHHHHHHHH
YTVAMPLLGRIADAYGHRRLFLAALGVFVGGSIGCALADSVWSLVAWRIVQAIGGGAVLP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
IGLAISMDEVKPIHHATALGIMGAAGEAGGVLGPAYGGLISQIQLLDVDGWRWVFWLNIP
EEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHEEEEEECCCEEEEEEEECC
LGAALAWAIIRTLPDRPGNRGAIDYIGGGLIAVSLTALTVALSRSLGSLAIEPSAESGNL
HHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
DQYAVQWTSPLTIGLLVLAVLSFIGFIWWERRTTTPLIELSAFRTPAFSAANITNVLVGM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
ALIVGMVNVPFFVGTVLAGDALSGGLTLMRLTMMIPIGAVLGGMLMRKISARLVASLGMI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTAVGFALLGFWKAETNQFQLTIYLLLTGTGFGLVLPALSAAAIGTVARESMGTAAGLLN
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRMVGITLGVSALASWSLAYRASLNSTLVFTMEDFNTGAAQLALTQNEMTVYHSTFFAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEHHHHHHHH
AVVCLIALIPIWWLPRERSEGDTPLFA
HHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]