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The map label for this gene is yqjC [H]

Identifier: 159898530

GI number: 159898530

Start: 2485652

End: 2486074

Strand: Direct

Name: yqjC [H]

Synonym: Haur_2006

Alternate gene names: 159898530

Gene position: 2485652-2486074 (Clockwise)

Preceding gene: 159898529

Following gene: 159898531

Centisome position: 39.17

GC content: 51.06

Gene sequence:

>423_bases
ATGGAGCAATTGCTCACGCGAGTTGATCATCTGGGCTTGGCCGTGCACGATCTTGAGCAAGCGATTGCCAGTTATCGCCA
GCAACTCGCGCTTGATGCTTGGGAAATTATCGAGATGCCGGAACGGCATATGCGGGTTGCGGTGGGTCAGGTTGGTGGCA
CATTACTTGAATTAATCGCCCCGACCAGCCCTGATGCAGCTTTTGCCAAATTTTTGGCTGAACGCGGCGAGGGGATTCAT
CATGTGGCCTACACCGTCGAAGATATTGATCATGCTTTAGAATCTTTGCAAGCCCAAGGTGTACGCCTGATCGATCACCA
GGCGCGGCCTGGAATTCATGGAACTCGGATTGCCTTTATTCACCCCAAAGCCTTACATGGTGTGTTAACTGAATTAGTCG
AACATCCCAAAGCGACAGTCTAA

Upstream 100 bases:

>100_bases
TCTATCTAGTATCTCAGCTATTGCCAAGCCTTTACGTTTGATTATGGAAGCGTTACACTTAATCCAAATGATGATTTTTG
GACGTGTTTGTGAGGATGCA

Downstream 100 bases:

>100_bases
CGCAGTGTGCTAACATAGTGCGTCATGATGGCCTATTTAAGCAACGAATAGGCTCAAGCTTATGTTACAATGACAAACCA
ATCAGGATTTTTGGGGCAAT

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIAPTSPDAAFAKFLAERGEGIH
HVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFIHPKALHGVLTELVEHPKATV

Sequences:

>Translated_140_residues
MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIAPTSPDAAFAKFLAERGEGIH
HVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFIHPKALHGVLTELVEHPKATV
>Mature_140_residues
MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIAPTSPDAAFAKFLAERGEGIH
HVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFIHPKALHGVLTELVEHPKATV

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=129, Percent_Identity=34.8837209302326, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506387, Length=130, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15436; Mature: 15436

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
PTSPDAAFAKFLAERGEGIHHVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFI
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEE
HPKALHGVLTELVEHPKATV
CHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEQLLTRVDHLGLAVHDLEQAIASYRQQLALDAWEIIEMPERHMRVAVGQVGGTLLELIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
PTSPDAAFAKFLAERGEGIHHVAYTVEDIDHALESLQAQGVRLIDHQARPGIHGTRIAFI
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEE
HPKALHGVLTELVEHPKATV
CHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]