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The map label for this gene is pkn1 [H]

Identifier: 159898518

GI number: 159898518

Start: 2460959

End: 2461873

Strand: Reverse

Name: pkn1 [H]

Synonym: Haur_1994

Alternate gene names: 159898518

Gene position: 2461873-2460959 (Counterclockwise)

Preceding gene: 159898519

Following gene: 159898512

Centisome position: 38.79

GC content: 55.19

Gene sequence:

>915_bases
ATGTTTATGCGGGGTTTCTATGCGCTCGTAGCGCTACTCTTACTATCGGCTTGTGAAGCATCGGACGCGGGATCAGCAGG
CGAAACACCACCAACCGCAGAACAAACTGCAACACCAGTCGTCACGCCAACGATGGCCGCTGGAACAACGCGGATTGATG
CGGCAGGTATAGCTCAAGTCTGGGTTCCTGCTGGCTGTTTTATGATGGGAACAGACCCAGCGACACTGACTGAAACACCA
CCTGCATGGGCCCGTGGCGCACTGGATAGCGAGCAGCCACAACACGAAGTTTGCTTAACCAAAGGCTACTGGATCGACCA
ATACGAGGTTTCTAACGCCGACTACCAGAAATTTATTGACGCTGGCGGCTATGAGCAGGAACAATATTGGTCGCCCAACG
GCTGGCGCTGGCGTAAATCTCGCCGCAATGTGCCGATTGAATGCCCAGATCAGCAGTCAAATCATCCACGCGTTTGTATT
ACATGGTACGAGGCCGAAGCCTACAGTCGTTGGCGTGGCGGTCGCTTGCCAACCGAAGCCGAATGGGAATACGCCGCCCG
TGGCCCAGAATCACGGATCTATCCATGGGGCAATAGCTTCGATGCGACTCGGGCTAACGTGATTGATAGTACCGGACTCG
TCGCGGTTGGCAGCTATCCCAATGGGGTAAGTTGGGTTGGTGCCCATGATATGGCTGGCAATGCAATGGAGTGGGTGCAG
GATTGGCTTGATATTGGCTACTATGCAGATCGCGTGCGTGACGACCCACCAGGCCCAGCCGAGGGTATGCGGAAGGTCGA
AAAAGGTGGCTGGTGGGGCAGTAATGCCTTTGTTGCCCGCTCAGCCTACCGCCACTTTGAAGATCTGCCAACCTATCAGG
ATCATCATATCGGGGTGCGCGTCGTGACTCCATAA

Upstream 100 bases:

>100_bases
AAGATCGGCGCGTGAGTTAATCGCTCTTTTGGGTGATTACGCCGCTAGCAGCGCCCGCTAGACTTCAGCCCACATGGTGC
AGTGCATATGGGAGGTCTTG

Downstream 100 bases:

>100_bases
CCACGACCATGGACTGGTCACGATCATCTGTTAGATCGTGACCAGTCCAGCGATGATTACCTGCTAGCGACGTTCAAACG
TTACCCGCGCCACGCCTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQVWVPAGCFMMGTDPATLTETP
PAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFIDAGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCI
TWYEAEAYSRWRGGRLPTEAEWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQ
DWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVRVVTP

Sequences:

>Translated_304_residues
MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQVWVPAGCFMMGTDPATLTETP
PAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFIDAGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCI
TWYEAEAYSRWRGGRLPTEAEWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQ
DWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVRVVTP
>Mature_304_residues
MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQVWVPAGCFMMGTDPATLTETP
PAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFIDAGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCI
TWYEAEAYSRWRGGRLPTEAEWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQ
DWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVRVVTP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=272, Percent_Identity=31.9852941176471, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI38202250, Length=297, Percent_Identity=29.6296296296296, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI257470977, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI194248087, Length=215, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI194248088, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI194248090, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226437577, Length=102, Percent_Identity=37.2549019607843, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130397, Length=258, Percent_Identity=29.4573643410853, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33839; Mature: 33839

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEECCCCHHHH
WVPAGCFMMGTDPATLTETPPAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFID
HHCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCHHEEEECCEEEEEEECCCCHHHHHHH
AGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCITWYEAEAYSRWRGGRLPTEA
CCCCCHHHCCCCCCCEEHHHCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHCCCCCCCCC
EWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQ
CCHHHHCCCCCCEECCCCCCCCCHHHEECCCCEEEECCCCCCCEEECCCCCCCCHHHHHH
DWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
VVTP
EECC
>Mature Secondary Structure
MFMRGFYALVALLLLSACEASDAGSAGETPPTAEQTATPVVTPTMAAGTTRIDAAGIAQV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEECCCCHHHH
WVPAGCFMMGTDPATLTETPPAWARGALDSEQPQHEVCLTKGYWIDQYEVSNADYQKFID
HHCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCHHEEEECCEEEEEEECCCCHHHHHHH
AGGYEQEQYWSPNGWRWRKSRRNVPIECPDQQSNHPRVCITWYEAEAYSRWRGGRLPTEA
CCCCCHHHCCCCCCCEEHHHCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHCCCCCCCCC
EWEYAARGPESRIYPWGNSFDATRANVIDSTGLVAVGSYPNGVSWVGAHDMAGNAMEWVQ
CCHHHHCCCCCCEECCCCCCCCCHHHEECCCCEEEECCCCCCCEEECCCCCCCCHHHHHH
DWLDIGYYADRVRDDPPGPAEGMRKVEKGGWWGSNAFVARSAYRHFEDLPTYQDHHIGVR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
VVTP
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]