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The map label for this gene is lgrC [H]

Identifier: 159898401

GI number: 159898401

Start: 2233390

End: 2237967

Strand: Direct

Name: lgrC [H]

Synonym: Haur_1877

Alternate gene names: 159898401

Gene position: 2233390-2237967 (Clockwise)

Preceding gene: 159898400

Following gene: 159898402

Centisome position: 35.19

GC content: 50.63

Gene sequence:

>4578_bases
ATGTCGGATGCGATGATCGAGGGATTTCGGCTTTCCCCACAGCAACAGCATGTTTGGGCGCTCCAGCAATTGGATTCAGC
CCAGCCTTATCGTACTCAGGGAACTATCGTGATTGAAGGCTCCCTCGATATTGCTCGCTTGCAGGCTAGTTTGTTGCAGG
TTGTACAGCGCTACGAAATTTTGCGCACAACCTTTCACTATCTCCAAGGGATGGCCTTGCCGTTGCAGGTGGTTACCGAA
TTAAGCGAACTAGCATTGCCAAGCTATGATCTGAGCGAACATAGTTTGACTGATTTGCAAAGCCAATTGGCTCAGCAAGC
CTTTGATTTTGCTGCTGGCCCATTGCTGCATGCCTGGCTTGGGCGTGAACATGCGCTAAAACATTATTTGCTGTTGAGTG
TGCCAACGCTCTGTGCTGATAACCTGAGTTTGGTCAACTTAACCAGCGAGCTGGCGGCGATTTATGCTGCCGAGCCAACT
ACCGATGAGCCAATGCAATATATCGATATTGCTGAGTGGCAGCACGAACTATTGGAAGCTGAAGAAACCGCTGCTGGCCG
CAGTTACTGGCAACAACAAACCTGGCACGATGCGATTACCGTGCGGCCAGCGTTTGTTGCCAATCAAGCAGCGGCCCAAA
CGTTTCAACCGCAGCAATTGCCAATTCCGCTGACTGAACAACTAATTGAGCTGCTTAATCAGGCAAGTCAAACTTTAGCT
GTGCCTGCTTCAGCGCTTGCCTTGGCTGCTTGGCGAACCTTGTTGTGGCGCTTGAGTGATCAAACCAATGGTGTGGTTGG
CGTGGTTTGTGATGGGCGCAAATATGCCGAGCTTGAAACCACGCTTGGTTTATTTGCCAAAGCCGTACCGCTGGCTAGCC
CGTTGGCAGCAGACCAGCAGTTTGGTCAATTGGTCAAACAAGTGCAGCAAGAATATGTGGAGGCCTATGCTTGGCAAGAA
AGTTTTCATTGGCCTGCAGAAGTGTCCAGTCAATTGGCCTTTTTCCCCTTTGGCTTTGAAGCGCTGACCACACCCAAACC
GCTGGTGATGGCTAATCTCAGCTTTCAAGTCGTGCAGCAACGGGCTACGCTCAATCCATATGCAGCCCACTTAACTTGGT
TCAACCAACCCCAAGGATTTGCCGCTAGCCTGAATTTTGATGCTGGGTTGATTGCGTCATCGAGTGCTGAACGGTTGATT
GAGCAATATCAAACCCTTTTGACTGCTGCACTGAGCAACTTGAACACAAGCTTGGCTCAACTGCCAATTGTGGGTACAAA
CGAACGTCAACAGCTATTAATTGAATTTAATCAAACAGCCGAGCCATTTGACGCTGCACGTTGCTTTCATGAGTTGTTTA
GCGCTCAAGCAGCGATTACACCTGATCACCCAGCGGTTGTGGTTGAAGACCAACAACTGAGCTATGCAGAACTTGAGGCA
CGTTCCAATCAACTGGCGCGAGAGTTGCTGGCCCGGGGAGTTCGCCCTGATCAACCAGTTGCTTTAGCCTTGGATCGCTC
GCTCAACCTGCTGGTGGGTATTTTGGGTATTCTCAAGGCTGGCGGAGCTTATGTACCGCTGGATTTGGGATTGCCCAAAG
AGCGTTTGGGCTTTATGCTGGGCGATATTCAAGCCTCAATTGTGGTGAGTGAAACCAGCCTGCAAGCCCAATTGCCTGAG
CATGCTGCCGACTATCTTTGGCTGGATCAAGCTTGGCCGACGATTGCCGAGCATTCAAGCGAACCTGTTGCTGCTTCGGC
GGTTCCTTCTAACTTGATGTATATCATTTATACCTCTGGTTCGACTGGCCAACCCAAAGGCGTTGGGGTCAGCCATCAAA
GTCTTTATAACTATATTTCAAGTATTAGCCAACGGCTTAATCTGCCGCCACAGGCTAGTTTTGCCAGTGTCTCGACCTTT
GCCGCTGATCTTGGACATACGGCGATTTTTCCAACCCTAACAAATGGTGGCACGCTGCACCTTATTACTGCTGAGCGAGC
GAGCAATGCTAGCCAATTGGCCGATTATATGCAGCAGCATGCCGTTGATTGTCTTAAAATTGTGCCATCGCATTTGGCGG
CGCTCTTGGCTGTGGCTGAACCTGCGCGAGTCTTGCCACGTCAGCGCTTGATTCTGGGCGGCGAGGCGGTTAGTTGGAAG
TTGCTACAAACCTTGGCGCTACTTGCACCTGATTGCCAAGTATTCAACCACTACGGACCGACCGAAACAACGGTGGGTGT
GCTAACCAATCCACTGAGTGCGAATTTGCCAAGTGCTCAATCGGCAATACCAGCCTTGGGTCGTCCCATCGCTAACACCC
AAATCTATCTGCTCGATGTTCACGGTCAGCCTGTGCCATTGGGTATGACTGGCGAGCTGTATGTGGGGGGCGCGGCGCTG
GCACGTGGTTATTGGCAGCGACCTGCGATTACGGCTGAGCGGTTTGTGCCCGATGGCTTAAGTGGCCAAACTGGCAGTCG
CTTGTATCGTACTGGCGATGTAGCTCGCTATTTGCCTGATGGCAAACTTGAGTTTTTAGGCCGCGCTGATGATCAGGTGA
AAATTCGCGGCTTCCGGATTGAATTGGGTGAAATTGAAGCAGCGTTGCGTAACCACACGGCGATTGAACAAGCAGCGGTG
ATAGTGCGTGATGATCCTGCTGGCGATAAGCGTTTGGTAGCTTATTTGGTTGCAGGCCAACAACGCCCACTTTCGTTACG
CGAGTTGCGTAACTTTTTGAAACAGAGCCTGCCCGATTACATGGTTCCGGCGGCATTTGTGATGTTGGAACGACTGCCAT
TGAACGCTAACGGCAAACTTGATCGTCAAGCCTTACCAGCGCCTGAACAGCAACAAACCAAGGCTAGCACTCAGATTGTG
GCTCCACGAACCCCCGTTGAGACAACATTGGTTGACATTTGGAGCCAAGTGTTGGGTGGCAAGTCGGTGGGCATTAACAA
TAACTTTTTTGAGCTGGGCGGCGATTCAATTCTGAGTATTCAAATTATTGCCCGCGCCAGCCAAGCAGGCCTTAAGTTGA
CACCCAAGCAATTATTTGATCATCCGACAATTGCCGATTTGGCGCAAGTGGTGGCCACCACAACAGCAGATCAACAAGCT
CAGCAGCAATTGATAACTGGCCCTGTGCCGTTGACTCCGATTCAACATTGGTTTTTTGAGCAAGCCCTCGCCGAGCCGCA
GCATTATAATCAAGCAGTCTTTTTCGAAGTGCGCTTTGATCTCGATCCGGCGATTTTGGCTCAGGTGTTGCCTGAACTTG
TGCGCCATCACGATGCCTTGCGCCTACGATTTAGCCCGAGCGAACAAGGCTGGCAACAAGTTAATAGTGCCGATGTAGCG
GTCGAGTTGCTGCACATTAATCTGGCCGCTGCGCCAGCCGAGCAGCAGCGCCAGTTGATGGAGCAAAAAGCCACTGAACT
GCAAACTAGCCTTGATCTGATCAATGGCCCGTTGTTGCGTATGGCCTTGTTTGAGCTTGGATCCAATCAACCAAGTCGCT
TGTTGGTGATTGTGCATCACTTGGCGATTGATACTGTCTCGTGGCAGATTTTGTTTGCCGATTTACCGCTGGTATACGAG
CAAATTCGTCAGCAACAACCAATTAATTTACCAGCCAAAACCAACTCATTCAAAGATTGGGCTGAGCGCTTGCAACGCTA
TGCAGGTTCGGCTGAACTTGAGCGCGAAGTTGCCTATTGGCTTGATCCTACCCGCCAACAGGTTCGCCCACTACCAGTCG
ATTATGCTGCTGAAGCCCATGCCAATACGGTTGCAAGCACCCAAAATCTGAGCCTACATTTGAGTGTTGAGGAAACGAAG
GCCTTATTGGAAGTGGTTCCTCCGGTCTATAACACCCAAATTAACGATGCGCTATTGGCAGCCTTAACCCAAAGCATCAG
TCAATGGCAGGGCAATCCAAGCGTGTTAGTCGAGCTCGAAGGCCATGGTCGTGAAGATATCTTGGATGATTTGGATATTT
CGCGCACGGTTGGATGGTTTACTAGTCGCTTTCCGGTGTTGTTGCAAGCGAGCAAATCAGCCAATGCTGGCGATAGCCTA
CGCGCAACTAAAGAACAGTTGCGCCAAATTCCACAGCGCGGGATTGGCTATGGTTTATTGCGCTATTTGCGTGGCGATGC
CCAGCTGAGCCAGCAATTAGCCAATCTGCCCCAACCGCAACTGAGCTTTAATTATTTGGGCACGGTCGCCCACGATGTTT
CGCAAACTGGTCCATTGGCTTGGACGAGCGAATCGAGTGGGCCAACCCGTAGCCCCGCAGCCTTACGCCGCCATTACCTT
GATCTGACGATCTTGGTAACCGATCACATGTTACAGATGAATTGGACATATAGCCAAGCATTGCATAGTGCAGCGACGAT
TCAGCGCTTGGCTGAACGTTTTGTGTCCGCCTTACAAGCGATTATTCAGCATTGCCAACAACCCAATGCTGGTGGTTATA
CCCCTTCGGATTTTCCATCGGCCAACTTAAACCAAAAGAATTTGGATAGCTTTATCGCCAAATTACGCAACAGCGAGAAC
AGCACTCATGAAAGTTGA

Upstream 100 bases:

>100_bases
TGGCTCATGCTCGCTCGCCTTTTGTTGGCCCACGCAAAATTGTGGTGGGTATGGCCGAATCGGTTGATGCAGCGGCGATC
TAAGTGAGGAAGGGATTACT

Downstream 100 bases:

>100_bases
GAATTTAGAAGATATCTATGGTTTGTCGCCTATGCAAAAGGGGATGCTTTTTCATACCCTGCTTGTACCCAATTCGAGTG
CCTACCAAAATCAATCAGTT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1525; Mature: 1524

Protein sequence:

>1525_residues
MSDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEILRTTFHYLQGMALPLQVVTE
LSELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWLGREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPT
TDEPMQYIDIAEWQHELLEAEETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLA
VPASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQFGQLVKQVQQEYVEAYAWQE
SFHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQRATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLI
EQYQTLLTAALSNLNTSLAQLPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEA
RSNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFMLGDIQASIVVSETSLQAQLPE
HAADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSGSTGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTF
AADLGHTAIFPTLTNGGTLHLITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWK
LLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDVHGQPVPLGMTGELYVGGAAL
ARGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPDGKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAV
IVRDDPAGDKRLVAYLVAGQQRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIV
APRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFDHPTIADLAQVVATTTADQQA
QQQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFDLDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVA
VELLHINLAAAPAEQQRQLMEQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYE
QIRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAHANTVASTQNLSLHLSVEETK
ALLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELEGHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSL
RATKEQLRQIPQRGIGYGLLRYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYL
DLTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPSANLNQKNLDSFIAKLRNSEN
STHES

Sequences:

>Translated_1525_residues
MSDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEILRTTFHYLQGMALPLQVVTE
LSELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWLGREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPT
TDEPMQYIDIAEWQHELLEAEETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLA
VPASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQFGQLVKQVQQEYVEAYAWQE
SFHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQRATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLI
EQYQTLLTAALSNLNTSLAQLPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEA
RSNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFMLGDIQASIVVSETSLQAQLPE
HAADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSGSTGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTF
AADLGHTAIFPTLTNGGTLHLITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWK
LLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDVHGQPVPLGMTGELYVGGAAL
ARGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPDGKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAV
IVRDDPAGDKRLVAYLVAGQQRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIV
APRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFDHPTIADLAQVVATTTADQQA
QQQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFDLDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVA
VELLHINLAAAPAEQQRQLMEQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYE
QIRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAHANTVASTQNLSLHLSVEETK
ALLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELEGHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSL
RATKEQLRQIPQRGIGYGLLRYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYL
DLTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPSANLNQKNLDSFIAKLRNSEN
STHES
>Mature_1524_residues
SDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEILRTTFHYLQGMALPLQVVTEL
SELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWLGREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPTT
DEPMQYIDIAEWQHELLEAEETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLAV
PASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQFGQLVKQVQQEYVEAYAWQES
FHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQRATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLIE
QYQTLLTAALSNLNTSLAQLPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEAR
SNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFMLGDIQASIVVSETSLQAQLPEH
AADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSGSTGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTFA
ADLGHTAIFPTLTNGGTLHLITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWKL
LQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDVHGQPVPLGMTGELYVGGAALA
RGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPDGKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAVI
VRDDPAGDKRLVAYLVAGQQRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIVA
PRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFDHPTIADLAQVVATTTADQQAQ
QQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFDLDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVAV
ELLHINLAAAPAEQQRQLMEQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYEQ
IRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAHANTVASTQNLSLHLSVEETKA
LLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELEGHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSLR
ATKEQLRQIPQRGIGYGLLRYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYLD
LTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPSANLNQKNLDSFIAKLRNSENS
THES

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=544, Percent_Identity=25.3676470588235, Blast_Score=108, Evalue=6e-23,
Organism=Homo sapiens, GI187761343, Length=544, Percent_Identity=25.3676470588235, Blast_Score=108, Evalue=6e-23,
Organism=Homo sapiens, GI38505220, Length=509, Percent_Identity=23.7721021611002, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI28416953, Length=531, Percent_Identity=24.8587570621469, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI45580730, Length=375, Percent_Identity=25.8666666666667, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI42544132, Length=540, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI122937307, Length=245, Percent_Identity=26.1224489795918, Blast_Score=71, Evalue=8e-12,
Organism=Homo sapiens, GI157311624, Length=260, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI157311622, Length=260, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI13375727, Length=553, Percent_Identity=22.2423146473779, Blast_Score=67, Evalue=1e-10,
Organism=Escherichia coli, GI1786801, Length=594, Percent_Identity=36.5319865319865, Blast_Score=290, Evalue=4e-79,
Organism=Escherichia coli, GI1786810, Length=521, Percent_Identity=25.9117082533589, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI145693145, Length=525, Percent_Identity=25.9047619047619, Blast_Score=114, Evalue=5e-26,
Organism=Escherichia coli, GI221142682, Length=525, Percent_Identity=25.3333333333333, Blast_Score=113, Evalue=9e-26,
Organism=Escherichia coli, GI1788107, Length=568, Percent_Identity=25.3521126760563, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1790505, Length=528, Percent_Identity=23.8636363636364, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=660, Percent_Identity=24.5454545454545, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17556356, Length=566, Percent_Identity=24.3816254416961, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17560140, Length=532, Percent_Identity=21.2406015037594, Blast_Score=94, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531443, Length=530, Percent_Identity=20.7547169811321, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI32563687, Length=506, Percent_Identity=22.9249011857708, Blast_Score=88, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=362, Percent_Identity=24.3093922651934, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=379, Percent_Identity=24.5382585751979, Blast_Score=81, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=941, Percent_Identity=25.5047821466525, Blast_Score=252, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6319699, Length=550, Percent_Identity=22.5454545454545, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323182, Length=575, Percent_Identity=22.2608695652174, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648676, Length=657, Percent_Identity=27.2450532724505, Blast_Score=180, Evalue=7e-45,
Organism=Drosophila melanogaster, GI18859661, Length=518, Percent_Identity=24.5173745173745, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356947, Length=376, Percent_Identity=23.936170212766, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656500, Length=366, Percent_Identity=25.1366120218579, Blast_Score=84, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581924, Length=530, Percent_Identity=23.3962264150943, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653035, Length=377, Percent_Identity=24.4031830238727, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076582, Length=384, Percent_Identity=23.9583333333333, Blast_Score=76, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922652, Length=510, Percent_Identity=23.3333333333333, Blast_Score=75, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24582852, Length=385, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648257, Length=367, Percent_Identity=27.2479564032698, Blast_Score=70, Evalue=8e-12,
Organism=Drosophila melanogaster, GI20130357, Length=381, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 167720; Mature: 167589

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEI
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LRTTFHYLQGMALPLQVVTELSELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPTTDEPMQYIDIAEWQHELLEA
CHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
EETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQ
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
FGQLVKQVQQEYVEAYAWQESFHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCHHHCCCCCEEEECCHHHHHHH
RATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLIEQYQTLLTAALSNLNTSLAQ
HHCCCCCEEEEEEECCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
LPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEA
CCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHH
RSNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFML
HHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
GDIQASIVVSETSLQAQLPEHAADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSG
HCCEEEEEEECCHHHHHCCHHHHCEEEECCCCCHHHHCCCCCCCHHCCCCCEEEEEEECC
STGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTFAADLGHTAIFPTLTNGGTLH
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEE
LITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWK
EEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHEEECCCHHHHH
LLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDV
HHHHHHHHCCCHHHHHCCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEE
HGQPVPLGMTGELYVGGAALARGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPD
CCCEECCCCCCCEEECHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCEEECCCHHHHCCC
GKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAVIVRDDPAGDKRLVAYLVAGQ
CCEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHEEEEEECCCCCCHHEEHHHHCCC
QRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCEEE
APRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFD
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEEEEEHHCCCCEECHHHHCC
HPTIADLAQVVATTTADQQAQQQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFD
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCEEEEEEEEC
LDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVAVELLHINLAAAPAEQQRQLM
CCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCHHHEEEEEEEEEECCCHHHHHHHH
EQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHEEEEEEHHHHHHHH
QIRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAH
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCCHHHHHH
ANTVASTQNLSLHLSVEETKALLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELE
HHHHCCCCCEEEEEEHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
GHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSLRATKEQLRQIPQRGIGYGLL
CCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
RYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYL
HHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
DLTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPS
EEEEEEECCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ANLNQKNLDSFIAKLRNSENSTHES
CCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDAMIEGFRLSPQQQHVWALQQLDSAQPYRTQGTIVIEGSLDIARLQASLLQVVQRYEI
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LRTTFHYLQGMALPLQVVTELSELALPSYDLSEHSLTDLQSQLAQQAFDFAAGPLLHAWL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GREHALKHYLLLSVPTLCADNLSLVNLTSELAAIYAAEPTTDEPMQYIDIAEWQHELLEA
CHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
EETAAGRSYWQQQTWHDAITVRPAFVANQAAAQTFQPQQLPIPLTEQLIELLNQASQTLA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPASALALAAWRTLLWRLSDQTNGVVGVVCDGRKYAELETTLGLFAKAVPLASPLAADQQ
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
FGQLVKQVQQEYVEAYAWQESFHWPAEVSSQLAFFPFGFEALTTPKPLVMANLSFQVVQQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCHHHCCCCCEEEECCHHHHHHH
RATLNPYAAHLTWFNQPQGFAASLNFDAGLIASSSAERLIEQYQTLLTAALSNLNTSLAQ
HHCCCCCEEEEEEECCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
LPIVGTNERQQLLIEFNQTAEPFDAARCFHELFSAQAAITPDHPAVVVEDQQLSYAELEA
CCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHH
RSNQLARELLARGVRPDQPVALALDRSLNLLVGILGILKAGGAYVPLDLGLPKERLGFML
HHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
GDIQASIVVSETSLQAQLPEHAADYLWLDQAWPTIAEHSSEPVAASAVPSNLMYIIYTSG
HCCEEEEEEECCHHHHHCCHHHHCEEEECCCCCHHHHCCCCCCCHHCCCCCEEEEEEECC
STGQPKGVGVSHQSLYNYISSISQRLNLPPQASFASVSTFAADLGHTAIFPTLTNGGTLH
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEE
LITAERASNASQLADYMQQHAVDCLKIVPSHLAALLAVAEPARVLPRQRLILGGEAVSWK
EEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHEEECCCHHHHH
LLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGRPIANTQIYLLDV
HHHHHHHHCCCHHHHHCCCCCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEE
HGQPVPLGMTGELYVGGAALARGYWQRPAITAERFVPDGLSGQTGSRLYRTGDVARYLPD
CCCEECCCCCCCEEECHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCEEECCCHHHHCCC
GKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAVIVRDDPAGDKRLVAYLVAGQ
CCEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHEEEEEECCCCCCHHEEHHHHCCC
QRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAPEQQQTKASTQIV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCEEE
APRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARASQAGLKLTPKQLFD
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEEEEEHHCCCCEECHHHHCC
HPTIADLAQVVATTTADQQAQQQLITGPVPLTPIQHWFFEQALAEPQHYNQAVFFEVRFD
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCEEEEEEEEC
LDPAILAQVLPELVRHHDALRLRFSPSEQGWQQVNSADVAVELLHINLAAAPAEQQRQLM
CCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCHHHEEEEEEEEEECCCHHHHHHHH
EQKATELQTSLDLINGPLLRMALFELGSNQPSRLLVIVHHLAIDTVSWQILFADLPLVYE
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHEEEEEEHHHHHHHH
QIRQQQPINLPAKTNSFKDWAERLQRYAGSAELEREVAYWLDPTRQQVRPLPVDYAAEAH
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCCHHHHHH
ANTVASTQNLSLHLSVEETKALLEVVPPVYNTQINDALLAALTQSISQWQGNPSVLVELE
HHHHCCCCCEEEEEEHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
GHGREDILDDLDISRTVGWFTSRFPVLLQASKSANAGDSLRATKEQLRQIPQRGIGYGLL
CCCCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
RYLRGDAQLSQQLANLPQPQLSFNYLGTVAHDVSQTGPLAWTSESSGPTRSPAALRRHYL
HHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
DLTILVTDHMLQMNWTYSQALHSAATIQRLAERFVSALQAIIQHCQQPNAGGYTPSDFPS
EEEEEEECCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ANLNQKNLDSFIAKLRNSENSTHES
CCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA