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The map label for this gene is dhbC [H]

Identifier: 159898326

GI number: 159898326

Start: 2091069

End: 2092256

Strand: Direct

Name: dhbC [H]

Synonym: Haur_1802

Alternate gene names: 159898326

Gene position: 2091069-2092256 (Clockwise)

Preceding gene: 159898325

Following gene: 159898327

Centisome position: 32.95

GC content: 54.8

Gene sequence:

>1188_bases
ATGAGCAGTTTTGAACAAGAACGGCTACGCGAATCGGCGTGGCAATTGCTAGACAACTATCAAGCAGAATCGGCCTTTTT
CTTTGCATCGCCCAATCATACCTTGTTGGGCCAATTAAGCTATGTTGATTTGATCAGCCAAACCGCCTTGCTTGAGCTTG
AGCAACGAGTTAACGAGGCGCTGCAACGGGCTGAACGTGGTGGTGAAGTTAATCCAGTCGTGGTTGGGGCATTGCCTTTT
GCTCCCGATGCGGCGGCTTATTTGGCCTTGCCATCGCGGGTGGTTTGGGCTGGCCCATTGCACGCCGAAGCCCAACCCTA
TTGGCATAACCAGCGTTTGCCGCATTGCAGCATCGAGCCAATGCCAGCGCCCGAACACTACAAACAGGGTGTGGCTCAAG
CCTTGGCCAAAATGCAGGCTGGCGATTTGCAAAAAGTTGTGCTCTCACGCTCGTTGCAATTGACCGCCGAAGCACCGCTT
GATGTGAATTTGATTCTGGCGAATTTGGCACGTAACAACAAAACTGGCTATACCTTTGCGGTGCCGTTGCCAACCCGCCG
CGCGTTGGTTGGGGCTAGCCCTGAATTGTTGCTGGCGCGTAATGGCAATCAAGTGATCGCCAATCCCTTAGCTGGTTCGA
TTCCGCGCAGCGCCGACCCTGAAGAAGATGCGCGGCGGGCAGCAGGTTTGCTCGAATCGCCCAAAGATTTGCATGAACAT
AAGGTTGTAATTGAGGCGGTTGCGGCGGCCTTAGCGCCATTCTGTCTGAGCCTTGATGTGCCGCAACCAACCGTTATTTC
CACCGCGACGATGTGGCATCTCTCAACAACCTTGGTTGGCGAATTAAAGCCTGATGCACCTTCATCGTTGGGTTTGGCAT
TGGCCTTGCACCCAACTCCAGCGGTCTGTGGTACGCCTACCGAGGTCGCCCGCGCCGCCATCCGCGAAATCGAGCCGTTT
GATCGCGGCTTTTTCACGGGGATGGTTGGTTGGTGCAACGCCCAAGGCGATGGCGAATGGATTGTGACGATTCGTTGTGC
CGAAGTTGTTGATCAATCGTTGCGTTTATTTGCTGGTGCTGGGGTGGTACTAGGCTCGACTCCTGAAGCCGAGTTGGCCG
AAACTGCGGCGAAATTCCGCACGATGTTGTTGGCGATGGGCATCGATAGCGAAGGCGAGGTGGCCTAA

Upstream 100 bases:

>100_bases
TTGATGGAAAAAATCAATCAACAATCCGCCCAGCCAGTTGCGCGGGAAGTGGGTTTGAACTAAGCCAAGGCTGTGTAGCA
GGCAATTAAGGATGACGATC

Downstream 100 bases:

>100_bases
TGGCTGAGCTGACGCTTGGCCTTGAAGGCACAACTGCTTGGCCCGCCGAGTTTGCCGAACGCTATCGTAAGGCTGGCTAT
TGGGTTGATCAGACCTTTGG

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSSFEQERLRESAWQLLDNYQAESAFFFASPNHTLLGQLSYVDLISQTALLELEQRVNEALQRAERGGEVNPVVVGALPF
APDAAAYLALPSRVVWAGPLHAEAQPYWHNQRLPHCSIEPMPAPEHYKQGVAQALAKMQAGDLQKVVLSRSLQLTAEAPL
DVNLILANLARNNKTGYTFAVPLPTRRALVGASPELLLARNGNQVIANPLAGSIPRSADPEEDARRAAGLLESPKDLHEH
KVVIEAVAAALAPFCLSLDVPQPTVISTATMWHLSTTLVGELKPDAPSSLGLALALHPTPAVCGTPTEVARAAIREIEPF
DRGFFTGMVGWCNAQGDGEWIVTIRCAEVVDQSLRLFAGAGVVLGSTPEAELAETAAKFRTMLLAMGIDSEGEVA

Sequences:

>Translated_395_residues
MSSFEQERLRESAWQLLDNYQAESAFFFASPNHTLLGQLSYVDLISQTALLELEQRVNEALQRAERGGEVNPVVVGALPF
APDAAAYLALPSRVVWAGPLHAEAQPYWHNQRLPHCSIEPMPAPEHYKQGVAQALAKMQAGDLQKVVLSRSLQLTAEAPL
DVNLILANLARNNKTGYTFAVPLPTRRALVGASPELLLARNGNQVIANPLAGSIPRSADPEEDARRAAGLLESPKDLHEH
KVVIEAVAAALAPFCLSLDVPQPTVISTATMWHLSTTLVGELKPDAPSSLGLALALHPTPAVCGTPTEVARAAIREIEPF
DRGFFTGMVGWCNAQGDGEWIVTIRCAEVVDQSLRLFAGAGVVLGSTPEAELAETAAKFRTMLLAMGIDSEGEVA
>Mature_394_residues
SSFEQERLRESAWQLLDNYQAESAFFFASPNHTLLGQLSYVDLISQTALLELEQRVNEALQRAERGGEVNPVVVGALPFA
PDAAAYLALPSRVVWAGPLHAEAQPYWHNQRLPHCSIEPMPAPEHYKQGVAQALAKMQAGDLQKVVLSRSLQLTAEAPLD
VNLILANLARNNKTGYTFAVPLPTRRALVGASPELLLARNGNQVIANPLAGSIPRSADPEEDARRAAGLLESPKDLHEHK
VVIEAVAAALAPFCLSLDVPQPTVISTATMWHLSTTLVGELKPDAPSSLGLALALHPTPAVCGTPTEVARAAIREIEPFD
RGFFTGMVGWCNAQGDGEWIVTIRCAEVVDQSLRLFAGAGVVLGSTPEAELAETAAKFRTMLLAMGIDSEGEVA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=377, Percent_Identity=38.4615384615385, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87082077, Length=284, Percent_Identity=31.6901408450704, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787518, Length=319, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788114, Length=262, Percent_Identity=25.9541984732824, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=269, Percent_Identity=28.2527881040892, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42408; Mature: 42277

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFEQERLRESAWQLLDNYQAESAFFFASPNHTLLGQLSYVDLISQTALLELEQRVNEA
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LQRAERGGEVNPVVVGALPFAPDAAAYLALPSRVVWAGPLHAEAQPYWHNQRLPHCSIEP
HHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
MPAPEHYKQGVAQALAKMQAGDLQKVVLSRSLQLTAEAPLDVNLILANLARNNKTGYTFA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHEEEHHCCCCCCEEEE
VPLPTRRALVGASPELLLARNGNQVIANPLAGSIPRSADPEEDARRAAGLLESPKDLHEH
ECCCCCHHHHCCCCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
KVVIEAVAAALAPFCLSLDVPQPTVISTATMWHLSTTLVGELKPDAPSSLGLALALHPTP
HHHHHHHHHHHHHHHEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
AVCGTPTEVARAAIREIEPFDRGFFTGMVGWCNAQGDGEWIVTIRCAEVVDQSLRLFAGA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHCC
GVVLGSTPEAELAETAAKFRTMLLAMGIDSEGEVA
CEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSFEQERLRESAWQLLDNYQAESAFFFASPNHTLLGQLSYVDLISQTALLELEQRVNEA
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LQRAERGGEVNPVVVGALPFAPDAAAYLALPSRVVWAGPLHAEAQPYWHNQRLPHCSIEP
HHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
MPAPEHYKQGVAQALAKMQAGDLQKVVLSRSLQLTAEAPLDVNLILANLARNNKTGYTFA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHEEEHHCCCCCCEEEE
VPLPTRRALVGASPELLLARNGNQVIANPLAGSIPRSADPEEDARRAAGLLESPKDLHEH
ECCCCCHHHHCCCCCEEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
KVVIEAVAAALAPFCLSLDVPQPTVISTATMWHLSTTLVGELKPDAPSSLGLALALHPTP
HHHHHHHHHHHHHHHEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
AVCGTPTEVARAAIREIEPFDRGFFTGMVGWCNAQGDGEWIVTIRCAEVVDQSLRLFAGA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHCC
GVVLGSTPEAELAETAAKFRTMLLAMGIDSEGEVA
CEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]