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The map label for this gene is yfmC [H]

Identifier: 159898263

GI number: 159898263

Start: 2025269

End: 2026327

Strand: Direct

Name: yfmC [H]

Synonym: Haur_1739

Alternate gene names: 159898263

Gene position: 2025269-2026327 (Clockwise)

Preceding gene: 159898262

Following gene: 159898264

Centisome position: 31.91

GC content: 50.9

Gene sequence:

>1059_bases
ATGCAACGATTTTTGGCATTAATTGGCTTGGTCAGCATCTTGACTGCCTGTGGTTCATCGGCAGCAACCCAAGCACCGAC
AACCGCCCCAACTACCGCAGCCGCCGCAACCGCGACGACGGCCAGCGAACCAACCGCTGCTGCAACCGAAGCCGCCGCTG
AAGCAACCACCGCTCCGGCTGATAGCGCCGCTGGCACACGCACAATCAAGCACGTTTTGGGCGAAACCACGATCACTGGC
ACGCCGCAACGAGTGGTTGTGCTCGAATGGGTTTACGTCGAAAACTTGTTGGCCTTGGGCGTGCAACCAGTTGGCGTTGC
TGATATCGAAGCTTACAACACATGGGTCGATGTTCCAGTTGAATTGGGTCCAGATGCAACCGATGTGGGGACGCGTGGCG
AAGCTAATCTCGAAACGATTGCTTCACTCAAGCCCGATTTGATCATCACGCTCAAATATGATGCTGATAAAAACTATCCC
CAATACAGTGCAATTGCCCCAACCTTGGTGTTCAATCCCTATCCTGAATCAGGCGATCAATATGCTGAAATGATCGACAC
CTTCAACACGATTGCTGATGTATTGGGCAAAACCGAAGAAGCCAAAGCTGTGTTGAGCAAGATGGAGCAAACCTACGCTG
ATGCCAAGCAAACCTTGGCAACCGCTGGCTTTGAAAATGCGCCATATGTTTTGGCCCAAGCTTATACCTCAAACAACGCC
GCTGAAATTCGTTTGTTCACCGACAACTCGATGATTGCCAAATTGATCGCCAAAACTGGCCTCAAAAATGGCTGGACTGA
TAGCGCGTTCCAAGTTTATGGTTTCTCGACTGTTAGCAGCGAAGTGCTGGCTCAACTTGGCGATGTGCACTTTATGTATG
TTGTAGCCAATGATGACAACCCATTTGCTAGCGGCACGGTCAAGCCTTTCTGGGATAGCCTTGAGTTTGTCAAAAAAGGC
CAAGCTTACCCCTTGGGTGGCGACGTTTGGTTCTTTGGTGGCCCTTTGTCAGCCGAAGTCTTGGCCCAACGAGTGGTCAA
AAGCTTAACCAAACAATAA

Upstream 100 bases:

>100_bases
CCCAACGGGTCACCGAAGCGCTCTTGTCGGAAAGCAACTAAGCATTTTTTAGCGTTGGCCGTTTGAGCGTTCCAAGCGGC
TAGCAGAATAGATAAGCACA

Downstream 100 bases:

>100_bases
TTAATCAGCGTTGATTGATAGAGGATGTGTGTATGAGCGTAGGAAGTAGCCCACTTGCCCAAAGCCTGGAACGCGCCGCG
ACCTTAGATCAATACTTGGT

Product: periplasmic binding protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPADSAAGTRTIKHVLGETTITG
TPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPVELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYP
QYSAIAPTLVFNPYPESGDQYAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNA
AEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDNPFASGTVKPFWDSLEFVKKG
QAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ

Sequences:

>Translated_352_residues
MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPADSAAGTRTIKHVLGETTITG
TPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPVELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYP
QYSAIAPTLVFNPYPESGDQYAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNA
AEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDNPFASGTVKPFWDSLEFVKKG
QAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ
>Mature_352_residues
MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPADSAAGTRTIKHVLGETTITG
TPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPVELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYP
QYSAIAPTLVFNPYPESGDQYAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNA
AEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDNPFASGTVKPFWDSLEFVKKG
QAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786346, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082411, Length=296, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 37286; Mature: 37286

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPA
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
DSAAGTRTIKHVLGETTITGTPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPV
CCCHHHHHHHHHHCCCEECCCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEE
ELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYPQYSAIAPTLVFNPYPESGDQ
ECCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCHHH
YAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
AEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDN
EEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEEEECCCC
PFASGTVKPFWDSLEFVKKGQAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRFLALIGLVSILTACGSSAATQAPTTAPTTAAAATATTASEPTAAATEAAAEATTAPA
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
DSAAGTRTIKHVLGETTITGTPQRVVVLEWVYVENLLALGVQPVGVADIEAYNTWVDVPV
CCCHHHHHHHHHHCCCEECCCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEE
ELGPDATDVGTRGEANLETIASLKPDLIITLKYDADKNYPQYSAIAPTLVFNPYPESGDQ
ECCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCHHH
YAEMIDTFNTIADVLGKTEEAKAVLSKMEQTYADAKQTLATAGFENAPYVLAQAYTSNNA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
AEIRLFTDNSMIAKLIAKTGLKNGWTDSAFQVYGFSTVSSEVLAQLGDVHFMYVVANDDN
EEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEEEEECCCC
PFASGTVKPFWDSLEFVKKGQAYPLGGDVWFFGGPLSAEVLAQRVVKSLTKQ
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]