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The map label for this gene is yfmC [H]

Identifier: 159898262

GI number: 159898262

Start: 2024118

End: 2025209

Strand: Direct

Name: yfmC [H]

Synonym: Haur_1738

Alternate gene names: 159898262

Gene position: 2024118-2025209 (Clockwise)

Preceding gene: 159898261

Following gene: 159898263

Centisome position: 31.89

GC content: 53.11

Gene sequence:

>1092_bases
ATGGTTCGTTTTACCCGTTTACTCTCGTGTGGCTTGCTACTGACGGTGTTAGCAGCCTGTGGCGGTGCCGCCAGCACCCC
AACTAGCGCCCCAGCAGCGACCGCGACCACAGCTCCAACCGAGGCTGCTGCCGCTACGGCCACAACCGCGCCAACCGAAG
CCGCCGTGGTCGAAGCAACTGCCACCGCTGCTAGCGATACAACGACTACTTCTGGCAATCGCACCTTCACCCATGCCTTG
GGCGAAATCAGCATCCCCAATGTTCCGCAACGGGTGATCGCCCTTGATTGGATGTATTTGGAAGATGTGTTGGCCTTGGG
TGTGCAACCAGTCGGTGCGATCGACTTAGAAAATTACCCCAAGTGGGTCGATTTGCCGTTGACAATTGATCCCAGTGTCG
TTTCAATCGGCGCAAATCCAGCACCCGATTTTGAATCAATTGCTGCTTTGAAGCCTGACCTGATTTTGGTTGGCTCGTTG
CGGGGCGAAACGATTTACGATCAATTGAATGCCATCGCCCCAACCATGATGTTCAATCCCTATTTGAAAGAGGGCGAAGG
CCAGCCATACGACGAAATGACCACGACGTTCAGCACAATTGCCGCAGTGTTGGGCAAAGAAACCGAAGGCGCAGCCGTGT
TGAGCAAAATGGAACAAACCTTTGCTGATTCCAAAGCACAACTGGCAGCAGCTGGTTTGGCCGATGCTAACGTGTTGGTG
GCGCAAACCTATGCCAGCAACAACGCTGCTGAAGTGCGTTTGTTCACCGATAACGCCGCCGTCATGGAAATTATCAAGCG
TTTGGGCTTGAAAAACGCTTGGTCAGACCCAACCTATCAAGTTTGGGGCTTCTCATCGGTTGGCACTGAAGCGTTGGCTC
AGTTTGGTGATGTGCATATGCTTTACATAACCGAAGAAGATAATGATCCCTTCCAGAGCGCCGCGATCAAGCCCTATTGG
GATAGCTTGGAGTTTGTCAAAGCTGGCCAAGCACATACCTTGGATAGCCAAACTTGGACCTTTGGTGGCCCAATTGCCGC
CGAAGTGTTTGCCCAACGGGTCACCGAAGCGCTCTTGTCGGAAAGCAACTAA

Upstream 100 bases:

>100_bases
CATTGTGCATTCCCTATGGTTTATGTGCTGCGGAAGCATCAGATTCTCTCTTGCATGCGGATGCTGTTGGCAACCGCGCT
TAACTCTAGGAGTAACCTCA

Downstream 100 bases:

>100_bases
GCATTTTTTAGCGTTGGCCGTTTGAGCGTTCCAAGCGGCTAGCAGAATAGATAAGCACAATGCAACGATTTTTGGCATTA
ATTGGCTTGGTCAGCATCTT

Product: periplasmic binding protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEATATAASDTTTTSGNRTFTHAL
GEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYPKWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSL
RGETIYDQLNAIAPTMMFNPYLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLV
AQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHMLYITEEDNDPFQSAAIKPYW
DSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLSESN

Sequences:

>Translated_363_residues
MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEATATAASDTTTTSGNRTFTHAL
GEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYPKWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSL
RGETIYDQLNAIAPTMMFNPYLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLV
AQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHMLYITEEDNDPFQSAAIKPYW
DSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLSESN
>Mature_363_residues
MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEATATAASDTTTTSGNRTFTHAL
GEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYPKWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSL
RGETIYDQLNAIAPTMMFNPYLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLV
AQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHMLYITEEDNDPFQSAAIKPYW
DSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLSESN

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786346, Length=270, Percent_Identity=27.037037037037, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082411, Length=276, Percent_Identity=25.3623188405797, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 38306; Mature: 38306

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEAT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHEEEEH
ATAASDTTTTSGNRTFTHALGEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYP
HHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
KWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSLRGETIYDQLNAIAPTMMFNP
CEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
YLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEE
AQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHM
EEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEE
LYITEEDNDPFQSAAIKPYWDSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLS
EEEECCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHC
ESN
CCC
>Mature Secondary Structure
MVRFTRLLSCGLLLTVLAACGGAASTPTSAPAATATTAPTEAAAATATTAPTEAAVVEAT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHEEEEH
ATAASDTTTTSGNRTFTHALGEISIPNVPQRVIALDWMYLEDVLALGVQPVGAIDLENYP
HHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
KWVDLPLTIDPSVVSIGANPAPDFESIAALKPDLILVGSLRGETIYDQLNAIAPTMMFNP
CEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
YLKEGEGQPYDEMTTTFSTIAAVLGKETEGAAVLSKMEQTFADSKAQLAAAGLADANVLV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEE
AQTYASNNAAEVRLFTDNAAVMEIIKRLGLKNAWSDPTYQVWGFSSVGTEALAQFGDVHM
EEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEE
LYITEEDNDPFQSAAIKPYWDSLEFVKAGQAHTLDSQTWTFGGPIAAEVFAQRVTEALLS
EEEECCCCCCHHHCCCCCCCCCHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHC
ESN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]