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The map label for this gene is nrdR

Identifier: 159898108

GI number: 159898108

Start: 1839551

End: 1840003

Strand: Direct

Name: nrdR

Synonym: Haur_1584

Alternate gene names: 159898108

Gene position: 1839551-1840003 (Clockwise)

Preceding gene: 159898107

Following gene: 159898109

Centisome position: 28.98

GC content: 49.89

Gene sequence:

>453_bases
ATGCGCTGCCCGTATTGCACTGGCGAAAGTGCAGTGATTGATACTCGCGAACTTGATAATGGTGAAACCATCCGTCGTCG
CCGTCGCTGCAAACACTGTGATCGCCGCTTCACAACCTATGAACGGGTTGAATCTGTTAATGTCATGGTCGTTAAGAAAA
ATGGCGATCGTGAGCCATATGACCGCGAGAAATTATTGCGCGGTTTACGGGTTGCGGCCTATAAACGGCCTATCTCAGCC
GATGTAATTGACACGTTGGTCACTGAAGTCGAGGCTGCTCTGATCGCCTACGATGCCTTGGAAGTTCCTAGCTCGGTGAT
TGGCGAACAGGTGATGGAACGCTTACGCTCACTCGATGAGGTAGCCTACATCCGCTTTGCCTCGGTTTATCGTTCATTTA
GCGATCTTGGCAAGCTGCGTGAAGCTGTCGAAGAACTTATGGAAAAGGAATAA

Upstream 100 bases:

>100_bases
CAATCGCCAGCATTTGGTTGAGCCGATTAACTAAGCGCCAATACTGTGCGTCATGGGGCCATGGTATAATGAATCTACTA
AGCTAGGCCGAAGAGGAACT

Downstream 100 bases:

>100_bases
GTAGCTGCAATGGCAACTCCCGTATCTCAAGAAACCAAAACTGATTTGAAAGACGTGAAGCCTCAAGCTCCGGCAGTTCC
GTTGCTCTGGCGGCAGTTGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPYDREKLLRGLRVAAYKRPISA
DVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDEVAYIRFASVYRSFSDLGKLREAVEELMEKE

Sequences:

>Translated_150_residues
MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPYDREKLLRGLRVAAYKRPISA
DVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDEVAYIRFASVYRSFSDLGKLREAVEELMEKE
>Mature_150_residues
MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPYDREKLLRGLRVAAYKRPISA
DVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDEVAYIRFASVYRSFSDLGKLREAVEELMEKE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=46.9387755102041, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_HERA2 (A9B4R2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001544355.1
- GeneID:   5733471
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_1584
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   HAUR316274:HAUR_1584-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17383; Mature: 17383

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPY
CCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
DREKLLRGLRVAAYKRPISADVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDE
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VAYIRFASVYRSFSDLGKLREAVEELMEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCPYCTGESAVIDTRELDNGETIRRRRRCKHCDRRFTTYERVESVNVMVVKKNGDREPY
CCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
DREKLLRGLRVAAYKRPISADVIDTLVTEVEAALIAYDALEVPSSVIGEQVMERLRSLDE
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VAYIRFASVYRSFSDLGKLREAVEELMEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA