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The map label for this gene is plsC [H]

Identifier: 159897995

GI number: 159897995

Start: 1715095

End: 1715730

Strand: Direct

Name: plsC [H]

Synonym: Haur_1470

Alternate gene names: 159897995

Gene position: 1715095-1715730 (Clockwise)

Preceding gene: 159897994

Following gene: 159897996

Centisome position: 27.02

GC content: 53.46

Gene sequence:

>636_bases
GTGGTGCCATTAATTTATCAAATTGTACGGTTTGTTTGCCGTGTGCTGTTGGGGATGCGTGCTCGTCTCGTTGTCGAAGG
TCAAGAGCATCTTCCGGCGACTGGTGGCTATATTTTGGCCTCGAATCATGTGAGCAATTGGGACCCTGTGGCGCTTTCCT
TAGGTTCGCCTGGCCATCTGATTGGAGCGCTCGGTAAGCAAGAATTGTTTGAATTGCCGATTCTTGGGCGAATTGCCACG
GCGGTTGGCGGCATTCCCGTGCGGCGGGGTGAGGCTGATCGCGAGGCTTTAGCCCGTTGTAAAGCCGTCTTGCAATCGGG
TCAGCCATTAATTATTTTGCCTGAAGGCACGCGTTCGCGTTCTGGCGAGCTTTTAGAAGGCAAACATGGCATTATCGCCA
TGGCCCAACTGGCGAATGTGCCGATTGTGCCAGCCGCCGTGATTGGCACTAAAACGCTGGGTTGGCCATGGCGACGCTCA
ACGGTGATTGTGCGTTATGCTGCGCCAATTGTGGTTGATCGTAAAATTAAGGGCCACGAAGGCCGCCAACTCGCCTTGGA
CACGACCATGCATCAAATTGCCTCGATGCTGCCGCCAACCATGCAAGGCTTCTATAAACAAGCTTTGAGCGTCTAA

Upstream 100 bases:

>100_bases
GGAGCGTATGGTTTTGTGTTAGCTGGCAACAGTAGTGCCGATGTCTACTTTGATAACTTACGACTTCGTGCTTTGCCCTA
GCTGCTAGAAGGTTTGCGCC

Downstream 100 bases:

>100_bases
ATCAAACCCTCTCGCAGCATTTGCGAGAGGGTTTTTGTTGCCCTGCATTAATTATTAACTCATGTGATTCTGGTAGGCTT
AGCTTAATTAATCACGTTGT

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MVPLIYQIVRFVCRVLLGMRARLVVEGQEHLPATGGYILASNHVSNWDPVALSLGSPGHLIGALGKQELFELPILGRIAT
AVGGIPVRRGEADREALARCKAVLQSGQPLIILPEGTRSRSGELLEGKHGIIAMAQLANVPIVPAAVIGTKTLGWPWRRS
TVIVRYAAPIVVDRKIKGHEGRQLALDTTMHQIASMLPPTMQGFYKQALSV

Sequences:

>Translated_211_residues
MVPLIYQIVRFVCRVLLGMRARLVVEGQEHLPATGGYILASNHVSNWDPVALSLGSPGHLIGALGKQELFELPILGRIAT
AVGGIPVRRGEADREALARCKAVLQSGQPLIILPEGTRSRSGELLEGKHGIIAMAQLANVPIVPAAVIGTKTLGWPWRRS
TVIVRYAAPIVVDRKIKGHEGRQLALDTTMHQIASMLPPTMQGFYKQALSV
>Mature_211_residues
MVPLIYQIVRFVCRVLLGMRARLVVEGQEHLPATGGYILASNHVSNWDPVALSLGSPGHLIGALGKQELFELPILGRIAT
AVGGIPVRRGEADREALARCKAVLQSGQPLIILPEGTRSRSGELLEGKHGIIAMAQLANVPIVPAAVIGTKTLGWPWRRS
TVIVRYAAPIVVDRKIKGHEGRQLALDTTMHQIASMLPPTMQGFYKQALSV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 22783; Mature: 22783

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPLIYQIVRFVCRVLLGMRARLVVEGQEHLPATGGYILASNHVSNWDPVALSLGSPGHL
CCCHHHHHHHHHHHHHHCCHHEEEEECHHCCCCCCCEEEECCCCCCCCCEEEECCCCCHH
IGALGKQELFELPILGRIATAVGGIPVRRGEADREALARCKAVLQSGQPLIILPEGTRSR
HHHCCHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
SGELLEGKHGIIAMAQLANVPIVPAAVIGTKTLGWPWRRSTVIVRYAAPIVVDRKIKGHE
CCCEECCCCCEEEEEHHCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCEEEECCCCCCC
GRQLALDTTMHQIASMLPPTMQGFYKQALSV
CCEEEHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVPLIYQIVRFVCRVLLGMRARLVVEGQEHLPATGGYILASNHVSNWDPVALSLGSPGHL
CCCHHHHHHHHHHHHHHCCHHEEEEECHHCCCCCCCEEEECCCCCCCCCEEEECCCCCHH
IGALGKQELFELPILGRIATAVGGIPVRRGEADREALARCKAVLQSGQPLIILPEGTRSR
HHHCCHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
SGELLEGKHGIIAMAQLANVPIVPAAVIGTKTLGWPWRRSTVIVRYAAPIVVDRKIKGHE
CCCEECCCCCEEEEEHHCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCEEEECCCCCCC
GRQLALDTTMHQIASMLPPTMQGFYKQALSV
CCEEEHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]