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The map label for this gene is mprA [H]

Identifier: 159897844

GI number: 159897844

Start: 1524061

End: 1525092

Strand: Reverse

Name: mprA [H]

Synonym: Haur_1315

Alternate gene names: 159897844

Gene position: 1525092-1524061 (Counterclockwise)

Preceding gene: 159897845

Following gene: 159897843

Centisome position: 24.03

GC content: 56.88

Gene sequence:

>1032_bases
TTGAGCTTCATTCTGTTGCTTGATGAGGATCGGGCGTTTTCGGCCACGCTCGCTCGTACTTTAGAGATGGCCAGTTATCG
GGTGATGCGCGAATGGACTGAAACCAGCGCTCGCGAGGTTGCCCGTACCCAACAGCCCGATCTCATTTTGCTCGATCTTG
AACTGGGCCGCGAACAAGGCTGGGCCTTGCTCGATGAATTGGTGAGTTTAGGCCTGCGGGTCATGGTGATGTCGCATCGC
AGCAGCGCCGAGGATATTGCCCGTGGCCTGCGGGCTGGCGCGACCGATTATATCACCAAGCCCTACCGCACCGAAGAATT
GCTGGCGCGGATTGCGATTCGCTTACGCCAAGCGCCACCACCCGCCTTGCAACGCGCCGATACGCGCACACCCAAGCTAG
CCGAGCCAGTCATCGAAACTCCTATGGCTGCACCAGCGGTTGAGGCTGAAGCGCCAACCCTGAATATTCCGCTTGGGCAA
CGCCTGCGCCAAGCCCGCAAACTGCGCAATATCTCGCTGGTTCAAGCCAATTTGGATACCAAAATCCAAATGTATTATAT
TCAGGCGATCGAAGAAGAGAAATATGCCTTGCTACCGCGTGGCACTGCCGCCGAAGAGATTGTGCAACGCTATGCCCAAT
TTTTAAGCGAAGATCCCGATCAGGCGTTGGCCGAGTTCCGACGTTTGCACCATAGCGATGTTGAAACCCTGCGCAATTTG
GGCGGCCAGCCGGTGCGCTATCGACGGCGCGTTTCGTGGCCGTTGGTGTTGAGTTTGGTTGCATTGCTAACCTGTGGGCT
AGCCTCTGGCGCGATTGCCTTGATCTTCCCTGAAGAAACCCGTAACGTCACAACCAATGTACGGGCGATGTTCAGCGACC
CAACTGCAACCCCGACGCTTACGCCAACCCCAACCGCTACGCCTAGCCCTACACCAACATTAACGCCGACCGCTACGCCT
AGCCCTACGCCAACATTAACACCCGAACCAAGCCCAACCCTTGATCCGAATGCGCCCACGGCGACACCATAA

Upstream 100 bases:

>100_bases
ACTTGACGATCGAGTCGATCTAACGTGCTATAATCGCTGCATTAGGCATGGTCAAGTTGGTTACGCCCTAGCGTAGCCTT
TGTGGATAGGAATTCTGGTT

Downstream 100 bases:

>100_bases
GGAGTTTGTATGTCAATTAAAGCTGATCGCTGGATTAAGCGCATGGCCCAAGAGCATGGCATGATCGAGCCATTTGTTGA
TGGTCAAGTGCGCGGTGGAG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Mycobacterial persistence regulator A [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQGWALLDELVSLGLRVMVMSHR
SSAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPPPALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQ
RLRQARKLRNISLVQANLDTKIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNL
GGQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTLTPTPTATPSPTPTLTPTATP
SPTPTLTPEPSPTLDPNAPTATP

Sequences:

>Translated_343_residues
MSFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQGWALLDELVSLGLRVMVMSHR
SSAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPPPALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQ
RLRQARKLRNISLVQANLDTKIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNL
GGQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTLTPTPTATPSPTPTLTPTATP
SPTPTLTPEPSPTLDPNAPTATP
>Mature_342_residues
SFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQGWALLDELVSLGLRVMVMSHRS
SAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPPPALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQR
LRQARKLRNISLVQANLDTKIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNLG
GQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTLTPTPTATPSPTPTLTPTATPS
PTPTLTPEPSPTLDPNAPTATP

Specific function: Member of the two-component regulatory system mprB/mprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a tr

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 37960; Mature: 37829

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQG
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
WALLDELVSLGLRVMVMSHRSSAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPP
HHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCC
PALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQRLRQARKLRNISLVQANLDT
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCEEEEECCCC
KIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNL
EEEEEEEEHHHCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GGQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTL
CCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCCCCCC
TPTPTATPSPTPTLTPTATPSPTPTLTPEPSPTLDPNAPTATP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFILLLDEDRAFSATLARTLEMASYRVMREWTETSAREVARTQQPDLILLDLELGREQG
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
WALLDELVSLGLRVMVMSHRSSAEDIARGLRAGATDYITKPYRTEELLARIAIRLRQAPP
HHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCC
PALQRADTRTPKLAEPVIETPMAAPAVEAEAPTLNIPLGQRLRQARKLRNISLVQANLDT
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCEEEEECCCC
KIQMYYIQAIEEEKYALLPRGTAAEEIVQRYAQFLSEDPDQALAEFRRLHHSDVETLRNL
EEEEEEEEHHHCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GGQPVRYRRRVSWPLVLSLVALLTCGLASGAIALIFPEETRNVTTNVRAMFSDPTATPTL
CCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCCCCCC
TPTPTATPSPTPTLTPTATPSPTPTLTPEPSPTLDPNAPTATP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA