Click here to switch to the map view.

The map label for this gene is gdhB [H]

Identifier: 159897778

GI number: 159897778

Start: 1457794

End: 1459932

Strand: Direct

Name: gdhB [H]

Synonym: Haur_1249

Alternate gene names: 159897778

Gene position: 1457794-1459932 (Clockwise)

Preceding gene: 159897777

Following gene: 159897779

Centisome position: 22.97

GC content: 50.16

Gene sequence:

>2139_bases
ATGTCGCGTTGGATTATTATCGTTGTTCTGATCTTTTCAGGTTTTTCTGCCCAATTTGTTCAACAATCGAACCCTGAGCT
TTCCCCTGCTGCTGTTCCTGCTGGCTTCACCCAAACTGTGGTTGTACCCTCGAATAGCCTTGATGCTCCAACTGCCTTTA
CTTGGTTGCCCTCTGGTGAGATGTTGATTACTCAGCAAAATGGTCAGTTGTTGGGTTGGAATGGCACAAGCACGCGCACC
GTAATGAGCCTTGGCAATCGAGTTTGTTACGATTTTGAGCGTGGTTTGCTGGGCATCGCGGTTGATCCCCAATTTACCAG
TGGTCGTCCATATGTCTATGTCTACTATACCTTTAATAAATTTAACCAAACTTCGAACAATTGCCCTCGCCAAAGCCCCA
GCACCAATCCGGTCAATCGAGTTTCACGCTTTACTTGGAGTAATAATGTGCTCGATATCAACTCGGAATCGGTCTTGATC
GACAATATTGGCTCATATAACGGCAATCACAATGCTGGCGATCTTGGCTTTGGCAAAGATGGCAAGTTGTATATCAGCGT
TGGCGATGGCGGTTGCGATTATCTCGATAGTGGCTGTGGTGGCGCAAACGATGCCTCGCGCGAACAGCACACCTTGCTTG
GCAAAATTTTACGCATCAATGCTGATGGTACGATTCCTAGCGATAATCCGTTTACTGGCAGCGGCACGGCCCGTTGTAAT
ACTGGCTCAGTGGCTAGCGGCACGATTTGCCAAGAAACTTGGGCTTGGGGTTTTCGCAATCCCTACCGTATAACCTTCGA
TCCCAATGCTAGCGGCGTGCGCCTGTTTGTCAACGATGTTGGCCAAAATGTGCGCGAAGAAATCGACGAAGTTGTGGCGG
GCAAGGATTATGGCTGGAATTGTCGCGAAGGTACGCGGGTCAATAATTCAACGGGGCCATGTTCGCCAACGCCCGCCAAT
ATGGTTGACCCAATTTATGAATATAGCCATGGCAACGCTGGCGCACCATTTACCAACTGTAATTCGATCACTGGTGGCGC
GTTTGTGCCTGCCAATACTTTTCCTAGCAATTACAGTGGTTATATGTTTGGCGATTATGTTTGCGGCAAGATTTTTATGA
TTTCAGCCCAAGCGCCCTACAATTCGGTTCTAACTTTCTCAGATGATCCTGGATCAGTCACGCATATGGCGTTTGGCCCG
AATGGCGGTCGCCAAGCGTTATTCTATGCGACCTATGCTAATGGTGGCGAGATTCGCCGAATTAGCTATGATGGTAGCAC
CAGCTTGAATTCTTCGTTTACAGCCAACCCCAGTTTTGGCGCGGCTCCCTTGGCCGTAACCTTTACCGCTAGCAATCCAA
GCAGCGGCGCAAGCTATTTGTGGAATTTTGGCAATGGCACGAGCCGCGAAACTAGCACGGCCAGCACATCCTACACTTAC
GCCAACAATGGCACCTACACTGCAACCCTGTATTTGCGCGGCAGCAATGGCGATTTATCGAATGTGAGCCAGGCGATTGT
GCGGGTTGGCGCAACTGCGCCGAACGCCAGCATCACCCAACCAAACTCAAGTGCCCAATTTGCGGTTGGCCAAACAATCC
AAGTGCGGGGGCAGGCCAGCGATGCCGAACAAGGCCAATTGCCAGCCAGCGGTTTATCGTGGAAAGTAATTTTGCATCAC
GATACCCATACCCACCCCTATTTGACCCAACCAACCACCAATAGTTTTAGCTTTACTGCGCCAGCCCCCGAAGATTTATT
GGCGGCCAGCAACAGCTATTTGGAGCTTGAGCTGACTGCGACTGACGATAGTGGCTTGAGCCATGTTGTTACCCAAACTA
TCCAGCCCCATAAAGTCAATGTGACCTTGGCCTCAACCCCGAATGCTAACGCCAACTTTGTGGTCAACAACGACCCGATC
GAAGCTGATGATCCGTTTATTTCGTGGGAAAACTACAGCCTACGCGTGACTGCACCAGCCTATGCTGATAGCAATCGTTG
GTGGCGTTTTGTGCGTTGGAGCGATAACAACACCAGCAATCCGCGCACCTTTACGACACCTGCCAGCGCTACGACTTACA
CCGCGGTCTACGAAGAATTTATCCCCTATCAGCTCTATTTGCCAGTTGTGCGCAAGTAA

Upstream 100 bases:

>100_bases
GGCTTGGAACGCCTAAACAGCCTTGGCTGTCGGAGCGAACACCACCGCGAGCAAGGTTTTTTGAGCTTGTTCGCGGTGGT
CGTGTTTTTAAGGAGGAAGT

Downstream 100 bases:

>100_bases
ATTATTGTTCTCTCACCCCCCCCAACCCCTCGCCTACTGCGGCAGGCGAGGGGAGTTCCAATGGTCATGGTGGTTCCCCC
TCTCCCGCAGGCGAGGCGAG

Product: PKD domain-containing protein

Products: NA

Alternate protein names: Glucose dehydrogenase B [pyrroloquinoline-quinone]; Soluble glucose dehydrogenase; s-GDH [H]

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGEMLITQQNGQLLGWNGTSTRT
VMSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNKFNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLI
DNIGSYNGNHNAGDLGFGKDGKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCN
TGSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWNCREGTRVNNSTGPCSPTPAN
MVDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSGYMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGP
NGGRQALFYATYANGGEIRRISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTY
ANNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQASDAEQGQLPASGLSWKVILHH
DTHTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTATDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPI
EADDPFISWENYSLRVTAPAYADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK

Sequences:

>Translated_712_residues
MSRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGEMLITQQNGQLLGWNGTSTRT
VMSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNKFNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLI
DNIGSYNGNHNAGDLGFGKDGKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCN
TGSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWNCREGTRVNNSTGPCSPTPAN
MVDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSGYMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGP
NGGRQALFYATYANGGEIRRISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTY
ANNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQASDAEQGQLPASGLSWKVILHH
DTHTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTATDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPI
EADDPFISWENYSLRVTAPAYADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK
>Mature_711_residues
SRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGEMLITQQNGQLLGWNGTSTRTV
MSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNKFNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLID
NIGSYNGNHNAGDLGFGKDGKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCNT
GSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWNCREGTRVNNSTGPCSPTPANM
VDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSGYMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGPN
GGRQALFYATYANGGEIRRISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTYA
NNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQASDAEQGQLPASGLSWKVILHHD
THTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTATDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPIE
ADDPFISWENYSLRVTAPAYADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK

Specific function: Oxidizes glucose to gluconolactone [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936955, Length=298, Percent_Identity=34.2281879194631, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI187936953, Length=298, Percent_Identity=34.2281879194631, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI124248546, Length=298, Percent_Identity=30.5369127516779, Blast_Score=115, Evalue=2e-25,
Organism=Escherichia coli, GI1787060, Length=406, Percent_Identity=22.9064039408867, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR019893
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 76812; Mature: 76681

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50093 PKD ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGE
CCCEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCC
MLITQQNGQLLGWNGTSTRTVMSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNK
EEEEECCCEEEEECCCCHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEC
FNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLIDNIGSYNGNHNAGDLGFGKD
CCCCCCCCCCCCCCCCHHHHHHEEEECCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCC
GKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCN
CEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCCCCCCCEEEC
TGSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWN
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHCHHHHHHHHHHHCCCCCCCC
CREGTRVNNSTGPCSPTPANMVDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSG
CCCCCEECCCCCCCCCCCCHHHCHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
YMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGPNGGRQALFYATYANGGEIRR
CEEECEEEEEEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEE
ISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTY
EEECCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEE
ANNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQAS
ECCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCEEEECCEEEEECCCC
DAEQGQLPASGLSWKVILHHDTHTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTA
CCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCCEEEECCCCHHHHHCCCCEEEEEEEE
TDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPIEADDPFISWENYSLRVTAPA
CCCCCHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCEEEECCEEEEEEECC
YADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK
EECCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure 
SRWIIIVVLIFSGFSAQFVQQSNPELSPAAVPAGFTQTVVVPSNSLDAPTAFTWLPSGE
CCEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCC
MLITQQNGQLLGWNGTSTRTVMSLGNRVCYDFERGLLGIAVDPQFTSGRPYVYVYYTFNK
EEEEECCCEEEEECCCCHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEC
FNQTSNNCPRQSPSTNPVNRVSRFTWSNNVLDINSESVLIDNIGSYNGNHNAGDLGFGKD
CCCCCCCCCCCCCCCCHHHHHHEEEECCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCC
GKLYISVGDGGCDYLDSGCGGANDASREQHTLLGKILRINADGTIPSDNPFTGSGTARCN
CEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHEEEEEEEECCCCCCCCCCCCCCCCEEEC
TGSVASGTICQETWAWGFRNPYRITFDPNASGVRLFVNDVGQNVREEIDEVVAGKDYGWN
CCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHCHHHHHHHHHHHCCCCCCCC
CREGTRVNNSTGPCSPTPANMVDPIYEYSHGNAGAPFTNCNSITGGAFVPANTFPSNYSG
CCCCCEECCCCCCCCCCCCHHHCHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
YMFGDYVCGKIFMISAQAPYNSVLTFSDDPGSVTHMAFGPNGGRQALFYATYANGGEIRR
CEEECEEEEEEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEE
ISYDGSTSLNSSFTANPSFGAAPLAVTFTASNPSSGASYLWNFGNGTSRETSTASTSYTY
EEECCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEE
ANNGTYTATLYLRGSNGDLSNVSQAIVRVGATAPNASITQPNSSAQFAVGQTIQVRGQAS
ECCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCEEEECCEEEEECCCC
DAEQGQLPASGLSWKVILHHDTHTHPYLTQPTTNSFSFTAPAPEDLLAASNSYLELELTA
CCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCCEEEECCCCHHHHHCCCCEEEEEEEE
TDDSGLSHVVTQTIQPHKVNVTLASTPNANANFVVNNDPIEADDPFISWENYSLRVTAPA
CCCCCHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCEEEECCEEEEEEECC
YADSNRWWRFVRWSDNNTSNPRTFTTPASATTYTAVYEEFIPYQLYLPVVRK
EECCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2671663; 10366508; 10508152 [H]