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The map label for this gene is murA [H]

Identifier: 159897366

GI number: 159897366

Start: 947328

End: 948614

Strand: Direct

Name: murA [H]

Synonym: Haur_0837

Alternate gene names: 159897366

Gene position: 947328-948614 (Clockwise)

Preceding gene: 159897365

Following gene: 159897367

Centisome position: 14.93

GC content: 53.85

Gene sequence:

>1287_bases
GTGGAAACCTTTGTCATTGAGGGCGGTCATCGCCTGAATGGGACGATTACGCCTGCCGGAAACAAAAACGCCGCCTTGCC
GTTGTTAGCGGCCTGCTTGCTCAGCGACCAACCAATTATTCTGCGCAATATGCCCGATATTGCCGATGTGCGAGTCAAGG
TACAGTTATTGCAGTCATTGGGCATCGAATGTAGCTGGCTCGAAGAGAATGTGCTGCGGGTTCATGCTGCCACGATCAAT
ACCTCAGAGCCAGATACTGCGCTTGCGCGGCGAATTCGGACCTCGATTTTGCTCGCAGGGCCGTTGTTGGTGCGCACTGG
GCGGGCAGTTTTAGCGCGGCCAGGCGGCGATTCGATTGGCCATCGGCGTTTGGATACGCACTTTTTGGCCCTCACTGCCT
TGGGTGCTGAAGTTGAAGTGACCAAACAAGCCTATGAACTCAAAGCCGATGGTTTGGTTGGCACGGATATTTTCCTTGAT
GAAATGAGCGTAACTGGGACTGAACAGGCGATCATGGCGGCTGTGTTGGCTTCTGGCACGACCACAATTGTCAACGCCGC
TTCTGAGCCACATGTCCAAGATCTGTGTCGTTGTTTATTTGCCATGGGCGCTAAAATCACGGGCATCGGCACCAATAGCT
TGCAAATTCAAGGGGTTTCGCGGCTGAATGGCACTGAATATACACTCGGCCCCGATTTTATGGAGGTTGGTTCGTTCATC
GGCTTGGCAGCAGTGACGGGGAGTAACATTCGCATCGCCAACGCACGCCCCGAAGAACATCGCATGACGCGGATTATGTT
TGGGCGTTTGGGTGTGACCTGGCAAGACGAAGGCCCAGATATTGTGATTCCTGCTGAGCAAGAGCTACGGGTGCGCGACG
ATTTGCACGGCGTTGTGCCCAAAATCGACGATATGCCATGGCCTGGCTTCCCCCCCGATCTGATGAGCATTGCCTTGGTG
ATTGCGACTCAAGCCCAAGGCACGGTGTTGATTCACGAAAAGATGTTTGATGGACGCTTATTCTTTGTTGATAAATTGCT
GAGTATGGGCGCACGGGTGATTTTGTGCGATCCACATCGGGCGGTGGTGGTTGGCCCAGCTAAACTGTATGGCGAACGCC
TGACCAGCCCCGATATTCGCGCTGGTATGGCCTTGGTCATTGCCGCTTTATGCGCCAAAGGCACGAGTATTATTTCGAAT
ATTGCCCAAATTGATCGGGGCTACCAACGGATTGAACAGCGGCTGGCTGCGCTTGGAGCGCGGATCGAACGCCGTCCTGC
TGAATAA

Upstream 100 bases:

>100_bases
CTGCGTGCCCGCCTGCGACGCAAACCCAAATCGATCCAAAAAACAACTGAGCCAACCGATCAATCCAACTCTGCTGCTTA
ACCATTGAGGATTATTATTC

Downstream 100 bases:

>100_bases
TGGCCTGTAAGGAGGGTCGGTGTGACCAAAGCTACCGAACAACGACATATTTTAATTGCTGATGACGATCCAGGGATTCG
TGGTCTGTTATGCGAGGTCT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSLGIECSWLEENVLRVHAATIN
TSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIGHRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLD
EMSVTGTEQAIMAAVLASGTTTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFI
GLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVPKIDDMPWPGFPPDLMSIALV
IATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHRAVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISN
IAQIDRGYQRIEQRLAALGARIERRPAE

Sequences:

>Translated_428_residues
METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSLGIECSWLEENVLRVHAATIN
TSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIGHRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLD
EMSVTGTEQAIMAAVLASGTTTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFI
GLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVPKIDDMPWPGFPPDLMSIALV
IATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHRAVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISN
IAQIDRGYQRIEQRLAALGARIERRPAE
>Mature_428_residues
METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSLGIECSWLEENVLRVHAATIN
TSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIGHRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLD
EMSVTGTEQAIMAAVLASGTTTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFI
GLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVPKIDDMPWPGFPPDLMSIALV
IATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHRAVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISN
IAQIDRGYQRIEQRLAALGARIERRPAE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=36.4896073903002, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46136; Mature: 46136

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSL
CCEEEEECCCEECCEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GIECSWLEENVLRVHAATINTSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIG
CCEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHEECHHHHCCCCEEEECCCCCCCC
HRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLDEMSVTGTEQAIMAAVLASGT
CHHHHHHHEEEHHCCCCEEEHHHHHHEECCCEEECEEEEECCCCCCHHHHHHHHHHHCCC
TTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFI
EEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEECCCCHHHHHHHH
GLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVP
EEEEECCCCEEEECCCCHHHHHHHHHHHHCCCEECCCCCCEEECCHHHHHHHHHHHCCCC
KIDDMPWPGFPPDLMSIALVIATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHR
CCCCCCCCCCCHHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCC
AVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISNIAQIDRGYQRIEQRLAALGA
EEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIERRPAE
HHHCCCCC
>Mature Secondary Structure
METFVIEGGHRLNGTITPAGNKNAALPLLAACLLSDQPIILRNMPDIADVRVKVQLLQSL
CCEEEEECCCEECCEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GIECSWLEENVLRVHAATINTSEPDTALARRIRTSILLAGPLLVRTGRAVLARPGGDSIG
CCEEEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHEECHHHHCCCCEEEECCCCCCCC
HRRLDTHFLALTALGAEVEVTKQAYELKADGLVGTDIFLDEMSVTGTEQAIMAAVLASGT
CHHHHHHHEEEHHCCCCEEEHHHHHHEECCCEEECEEEEECCCCCCHHHHHHHHHHHCCC
TTIVNAASEPHVQDLCRCLFAMGAKITGIGTNSLQIQGVSRLNGTEYTLGPDFMEVGSFI
EEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEECCCCHHHHHHHH
GLAAVTGSNIRIANARPEEHRMTRIMFGRLGVTWQDEGPDIVIPAEQELRVRDDLHGVVP
EEEEECCCCEEEECCCCHHHHHHHHHHHHCCCEECCCCCCEEECCHHHHHHHHHHHCCCC
KIDDMPWPGFPPDLMSIALVIATQAQGTVLIHEKMFDGRLFFVDKLLSMGARVILCDPHR
CCCCCCCCCCCHHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCC
AVVVGPAKLYGERLTSPDIRAGMALVIAALCAKGTSIISNIAQIDRGYQRIEQRLAALGA
EEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIERRPAE
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA