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The map label for this gene is gmhB [H]

Identifier: 159896771

GI number: 159896771

Start: 274132

End: 274671

Strand: Direct

Name: gmhB [H]

Synonym: Haur_0238

Alternate gene names: 159896771

Gene position: 274132-274671 (Clockwise)

Preceding gene: 159896770

Following gene: 159896772

Centisome position: 4.32

GC content: 47.22

Gene sequence:

>540_bases
ATGAGCCAACCAGCCGTGTTTATTGATCGTGATGGTACGATCAATGTTGAAGTTAATTATCTGCATCAGCCCGAATTGGT
TCAGCTTGAGCAAACTGTTGGTCAAGCGATCGCTCGTTTGAATCAAGCTGGATTTTTGGTGTTGGTCGTGACCAATCAAT
CAGGAATTGCTCGTGGCTATTATCGCGCTGAGGATATGCATTTGGTCCATCAGCGGATTAGTGAATTGTTACAGCCCTTT
AATGCCCATATTGATGCTTGGTATTATTGCCCGCATCATCCTGAGGTAACGGGCGATTGTGCTTGTCGCAAACCCAATTT
GGGTATGTTCGAGCAAGCTCAAGCCGAATTCGCGATCGATCTCAGTCGTTCGTGGATGATTGGCGATAAGCTGCTCGATG
TGCAAGCAGGCATCAATTTGGGCGTACCCGCAATTATGGTGGCAACTGGCTACGGCACACAGCATCAACACGATTTGCCT
GAGCATGCTATGCTGGTCGCAAATCTTAATGCTGCTGTCGATTTGATTGTGCAGGAGTAA

Upstream 100 bases:

>100_bases
AAGCTTTATTTGCCAAATAACGAGCTTGATCGACGCAATGGCGCAGAGATTGTGATGATCTCTGCGTTTTTTAATTAAAT
TTTATAGTTGAGATAGACCA

Downstream 100 bases:

>100_bases
GTATGCAACCCCAAGCACCGCAACCACTTCAACCACCACCAGTTCAAATCGTACCACCATGGATGATCTCAGCCACCTTC
GATTTGCCAGGCTTCCGAGT

Product: histidinol-phosphate phosphatase family protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGYYRAEDMHLVHQRISELLQPF
NAHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAIDLSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLP
EHAMLVANLNAAVDLIVQE

Sequences:

>Translated_179_residues
MSQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGYYRAEDMHLVHQRISELLQPF
NAHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAIDLSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLP
EHAMLVANLNAAVDLIVQE
>Mature_178_residues
SQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGYYRAEDMHLVHQRISELLQPFN
AHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAIDLSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLPE
HAMLVANLNAAVDLIVQE

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=156, Percent_Identity=40.3846153846154, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=31.0810810810811, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19899; Mature: 19768

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGY
CCCCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCE
YRAEDMHLVHQRISELLQPFNAHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAID
ECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE
LSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLPEHAMLVANLNAAVDLIVQE
CCCCEEECCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEEEEC
>Mature Secondary Structure 
SQPAVFIDRDGTINVEVNYLHQPELVQLEQTVGQAIARLNQAGFLVLVVTNQSGIARGY
CCCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCE
YRAEDMHLVHQRISELLQPFNAHIDAWYYCPHHPEVTGDCACRKPNLGMFEQAQAEFAID
ECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE
LSRSWMIGDKLLDVQAGINLGVPAIMVATGYGTQHQHDLPEHAMLVANLNAAVDLIVQE
CCCCEEECCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286; 12101286 [H]