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The map label for this gene is rsbRA [H]

Identifier: 159896649

GI number: 159896649

Start: 150124

End: 151197

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_0116

Alternate gene names: 159896649

Gene position: 150124-151197 (Clockwise)

Preceding gene: 159896646

Following gene: 159896650

Centisome position: 2.37

GC content: 47.77

Gene sequence:

>1074_bases
ATGAGTTTGCTACCCGCCGCCATCGACGATAACGAACTATCTCCTGCCCGCAAAACCTTGCTTGATCGCATCCATTTGGT
GTGGATATTTGTCAATGGCTCAACTGCATTAAGCTTGTTTTTCCTCTTTCTCTTCAATTTCTTTAGCGGCAACAGTGCTT
GGGTCCAAATGTTGATCTTATCGATCTCATCGATTGGCTCAACGGGGATTTTGTGGTATACCAATAGCAAGCCTGTTCAA
TGGCGTTTATGGGCAGCCTTGATTAGCTCGATGGTCGCATTACTTGAAATTGCACTTTTCTTCCAAAATGGCTATTTGAT
TGCAATTTCGGTCACGAGTGTGGTCAGTATCTATGCAGTTACCGCTGATCGCCACGAATTAATCACATGGTCGGCAGTGA
TTGGCGTGATTTTTACGATTATTTTTGCGATTTTGAATGGAGTTGAACAAACTCCGCCAAAATGGCTGAATGATTTACAC
CTCAACCTGCTAATTTCAAAAGTGTTGGTTCCGGCCTTTATTGGCGGCGGGATTGTGATGATTGCCTTGTTGCTGCTTGG
TTTGAGCAACACGCTGCGTCAATCACTCAACGAGGCCAATGAGCGCCGCCGAATTGCCGAAGAAGCTCAAGCAGCCCAAG
CTAAAACTTTGGCTCAGGTCGAGCGTCAAGCAGCTGAACAAGCTCGTTTGCTTGAATTGGTGCGCGACCTCGAAACGCCA
GTTATTCCAGTGCTCGATGGTGTGTTGGTGTTGCCAATCGTTGGTCACCTCGAAAGCAAACGGCTGGAAAATTTGACCGA
ATTGCTGCTGAATCGAGTTTCACAAGAGCGTGCCCACACGGTGTTGCTGGATATCACAGCGGTTTCAGTGGTTGATACGG
CTACTGCTCAGCACTTAATTCAACTAGCCCGCGCAATTCGTTTGCTGGGCGCTGAATGTGTGATTACCGGGATTCGCGCT
CATGTTGCGAGCACCTTGGTGGCACTGGGGATTACTTGGGAAGGCCTGCGCACCGCTGGCTCGTTGCGTGATGGAATTGC
CAAAATTATCGCTGAAAAGAATATTGCAATTTAG

Upstream 100 bases:

>100_bases
CACTGGCTTTGCTCGGTTTTGTCGTGTTATCAATAGTGGCAATGGTATCGCTCACCGCCCACGACATAGAAGATACCATT
CGAAAGAAAGGGCGTTCTGA

Downstream 100 bases:

>100_bases
GAATTTGGCTTGTGGTTTTTGATGATACTGATTTAACGCCCAACCGGATTGAAATGGCTCGTCGCGCTGCGACGGGTCAT
TTTATTGATCTGACCAGTAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLILSISSIGSTGILWYTNSKPVQ
WRLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAVTADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLH
LNLLISKVLVPAFIGGGIVMIALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETP
VIPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLIQLARAIRLLGAECVITGIRA
HVASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI

Sequences:

>Translated_357_residues
MSLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLILSISSIGSTGILWYTNSKPVQ
WRLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAVTADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLH
LNLLISKVLVPAFIGGGIVMIALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETP
VIPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLIQLARAIRLLGAECVITGIRA
HVASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI
>Mature_356_residues
SLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLILSISSIGSTGILWYTNSKPVQW
RLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAVTADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLHL
NLLISKVLVPAFIGGGIVMIALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETPV
IPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLIQLARAIRLLGAECVITGIRAH
VASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39038; Mature: 38907

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLIL
CCCCCCCCCCCCCCHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHH
SISSIGSTGILWYTNSKPVQWRLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAV
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHE
TADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLHLNLLISKVLVPAFIGGGIVM
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VIPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHH
QLARAIRLLGAECVITGIRAHVASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLLPAAIDDNELSPARKTLLDRIHLVWIFVNGSTALSLFFLFLFNFFSGNSAWVQMLIL
CCCCCCCCCCCCCHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHH
SISSIGSTGILWYTNSKPVQWRLWAALISSMVALLEIALFFQNGYLIAISVTSVVSIYAV
HHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHE
TADRHELITWSAVIGVIFTIIFAILNGVEQTPPKWLNDLHLNLLISKVLVPAFIGGGIVM
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IALLLLGLSNTLRQSLNEANERRRIAEEAQAAQAKTLAQVERQAAEQARLLELVRDLETP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VIPVLDGVLVLPIVGHLESKRLENLTELLLNRVSQERAHTVLLDITAVSVVDTATAQHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHH
QLARAIRLLGAECVITGIRAHVASTLVALGITWEGLRTAGSLRDGIAKIIAEKNIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]