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Identifier: 15925736

GI number: 15925736

Start: 38428

End: 39690

Strand: Reverse

Name: pre

Synonym: SA0029

Alternate gene names: 15925736

Gene position: 39690-38428 (Counterclockwise)

Preceding gene: 15925739

Following gene: 15925734

Centisome position: 1.41

GC content: 33.73

Gene sequence:

>1263_bases
ATGAGTTATGCAGTTTGTAGAATGCAAAAAGTGAAATCAGCTGGACTAAAAGGCATGCAATTTCATAATCAAAGAGAGCG
AAAAAGTAGAACGAATGATGATATTGACCATGAGCGAACACGTGAAAATTATGATTTGAAAAATGATAAAAATATTGATT
ACAACGAACGTGTCAAAGAAATTATTGAATCACAAAAAACAGGTACAAGAAAAACGAGGAAAGATGCTGTTCTTGTAAAT
GAGTTGCTAGTAACATCTGACCGAGATTTTTTTGAGCAACTGGATCCAGGAGAACAAAAACGATTTTTTGAGGAAAGTTA
TAAATTATTTTCCGAACGATATGGCAAGCAAAATATTGCTTATGCAACAGTTCATAATGATGAGCAAACCCCTCACATGC
ATTTAGGTGTTGTGCCTATGCGTGATGGAAAACTGCAAGGAAAAAATGTGTTTAATCGTCAAGAACTGTTATGGCTACAA
GATAAATTCCCCGAGCATATGAAAAAACAGGGTTTTGAGTTGAAGCGTGGTGAACGTGGCTCTGACCGTAAACATATTGA
GACAGCTAAATTTAAAAAACAAACTTTGGAAAAAGAGATTGATTTTCTAGAAAAAAATTTAGCAGTTAAAAAAGATGAAT
GGACTGCTTATAGCGATAAAGTTAAATCAGATTTAGAAGTACCAGCGAAACGACACATGAAAAGTGTTGAAGTGCCAACG
GGTGAAAAGTCTATGTTTGGTTTGGGAAAAGAAATAATGAAAACAGAAAAGAAACCAACCAAAAATGTTGTTATATCGGA
GCGTGATTATAAAAACTTAGTGACTGCTGCGAGAGATAACGATAGGTTAAAACAGCATGTTAGAAATCTCATGAGTACTG
ATATGGCGAGAGAATATAAAAAATTAAGTAAAGAACATGGGCAAGTTAAAGAAAAATATAGTGGTCTTGTAGAGCGATTT
AATGAAAATGTAAATGATTATAATGAGTTGCTTGAAGAAAACAAGTCTTTAAAGTCTAAAATAAGCGATTTAAAGCGTGA
TGTGAGTTTAATCTATGAAAGCACTAAGGAATTCCTTAAGGAACGTACAGACGGCTTAAAAGCCTTTAAAAACGTTTTTA
AGGGGTTTGTAGACAAGGTAAAGGATAAAACAGCACAATTCCAAGAAAAACACGATTTAGAACCTAAAAAGAACGAATTT
GAACTAACTCATAACCGAGAGGTAAAAAAAGAACGAAGTCGAGATCAGGGAATGAGTTTATAA

Upstream 100 bases:

>100_bases
TGAATATAAAGTATAGTGTGTTATACTTTACTTGGAAGTGGTTGCCGGAAAGAGCGAAAATGCCTCACATTTGTGCCACC
TAAAAAGGAGCGATTTACAT

Downstream 100 bases:

>100_bases
AATAAAAAAAGCACCTGAAAAGGTGTCTTTTTTTGATGGTTTTGAACTTGTTCTTTCTTATCTTGATACATATAGAAATA
ACGTCATTTTTATTTTAGTT

Product: plasmid recombination enzyme

Products: NA

Alternate protein names: Mobilization protein; Plasmid recombinase

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVN
ELLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPT
GEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERF
NENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEF
ELTHNREVKKERSRDQGMSL

Sequences:

>Translated_420_residues
MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVN
ELLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPT
GEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERF
NENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEF
ELTHNREVKKERSRDQGMSL
>Mature_419_residues
SYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNE
LLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQD
KFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPTG
EKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFN
ENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEFE
LTHNREVKKERSRDQGMSL

Specific function: The interaction of the RSA site and the PRE protein may not only serves a function in plasmid maintenance, but may also contributes to the distribution of small antibiotic resistance plasmids among Gram-positive bacteria

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the plasmid mobilization pre family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRE2_STAAM (P0A0C5)

Other databases:

- EMBL:   BA000017
- RefSeq:   NP_370555.1
- STRING:   P0A0C5
- EnsemblBacteria:   EBSTAT00000005785
- GeneID:   1119992
- GenomeReviews:   BA000017_GR
- KEGG:   sav:SAV0031
- eggNOG:   NOG112830
- GeneTree:   EBGT00050000025677
- HOGENOM:   HBG215720
- OMA:   EANEPRR
- ProtClustDB:   CLSK861687
- BioCyc:   SAUR158878:SAV0031-MONOMER
- InterPro:   IPR001668

Pfam domain/function: PF01076 Mob_Pre

EC number: NA

Molecular weight: Translated: 49661; Mature: 49530

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: BINDING 44-44 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKE
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
IIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIA
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCE
YATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQDKFPEHMKKQGFELKRGERG
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCC
GEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYK
CCHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLSKEHGQVKEKYSGLVERFNENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEFELTHNREVKKERSRDQGMSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKE
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHH
IIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIA
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCE
YATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQDKFPEHMKKQGFELKRGERG
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCC
GEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYK
CCHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KLSKEHGQVKEKYSGLVERFNENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEFELTHNREVKKERSRDQGMSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146