Click here to switch to the map view.

The map label for this gene is soxB [H]

Identifier: 15922727

GI number: 15922727

Start: 2398065

End: 2399639

Strand: Direct

Name: soxB [H]

Synonym: ST2396

Alternate gene names: 15922727

Gene position: 2398065-2399639 (Clockwise)

Preceding gene: 15922726

Following gene: 15922728

Centisome position: 88.99

GC content: 35.3

Gene sequence:

>1575_bases
ATGGTGAAGTTATATCCTAAAACAAGTTTAGGTATGGCTTTAGTATATATTTCTGGAGCAATATCATGGCTTATTGTAAT
GGGAATTGCTGCTTTATGGTTTAGGACAATTTTATTAAATCCTCATACGAATCCTGCCGTTGGATATGCTATTTCTCCCC
TTTATTACTTTCTAGTTACTCTTCATGGAATGTCTGCGATGTATATAATTGTTGAAGATCTAGCACTAGGAATATTTGCT
TATGCATTGTATAAGAGTGGAATGTCTGTAGTTCATTTCAGAACACTTACTGCCTTATTCTGGGTTTTAAATTTAGCACC
TATAGTAACTTTTGCTGGAGGTCCAATAACTGGTTGGTATATGTATCCTCCTTTAGCGTTGCAAACTCAATCATGGCTTA
ACTATCACACAGATGCATTAATAGGAATGGCATACTTCTTCCTATTCATAAATTCTGTAGCTGCTATATTAGCGTCATTG
TTTATGTTTATTGACGCTATAAAGACAAGACCAAAAGAGGGTAAAATACCAATCTTTGCCTCTTATGCTATGATGTTTGC
CGGTGCTCTAATCTTCTTAACAGAACCAGCATTGGCTGCTGGAGAATTATGGTATACATTATACTTCTGGGCTAATGTTC
CAGTTAATCCATTAACGTGGGTAGTTTTATTCTGGTTCTTTGGTCATCCAGTAGTTTATTATGTACCATTTACGGTATTT
GGCGGTTTGTATGCATTAATTCCGCATTATGCTGGAAGGCCATTATATAGTGAAAGGTGGGCTAGGTGGAACATAATTTT
GCTGTTTACTTTTAGTATGTTAGCTTGGGTTCATCACCTACAAACATTCCCATTACCAGTGTATATAAGAGCATTCATTA
CACCAACTACACTAATCTTAGCCGCAGGATCTGGTTTAACAGTATTGAATTTAGCTTTAACAATATTTTATAGTCCAACT
GGATATAACTATAAGGATCCAGTAGGTTTTGCAGCCCTAATAGCATACATAGGTTTTATATTAGCTGGGTTACAAGCATT
GATTCTTCCAATAAATATAACTAATGTAATTGTTCACAATACTTACTATGTAGTTGGACATTTCCATTTAATGATTTGGA
CAATAATTATAGTTGGAAGTGTAGCAATAATCCTAGATATGTTAAGAAATCAAGTAGGTGCTAAATTAGACTTCTCTTCT
TTAGGTAGAGGGTTCTTATTTGCAGGTCTATCTATGTGGACTGTTGGTGCACTCTTGACTGGCTATACAATGAGTTATGC
TGGCTATTTAGGGTTAATAAGGAGATGGGACGCATATCCGATTAAGTTCTTACCATTTATGGATGTTATGACTTATGGTG
CTATGATTATGGGATTGAGTTTTGTGTTTATTGCACTACCAATTGTTTTAACAATGATTAGAGTGGGAATCCCAATATTC
TGGACCCCAACTACTGGTGTTACAGCATCCCCTGGAATAACAATGAATACTCAGCCACCTAGTTCTGGAACACCTTCAAT
TACTAAAGAAGTAAGTACAAGTGATATGAATAATAAGGTAACAAAGTTAAAATAA

Upstream 100 bases:

>100_bases
TTTTATGCTCCAATGACTCCTGGTAATTACACGTTCCATTGTGCAGAGTATTGTGGTATTGGTCATTCTTATATGTATGG
TTATTTGTGGGTGATGTAAG

Downstream 100 bases:

>100_bases
ATTGATCTTTTTTTTTCTTTTAATCTGCTTTTATTTTAAAAGTAAATTTTTAAATCCTCTAACCCAAAATATTTTTTATG
ATAAAGTATTCTGGTATGAG

Product: quinol oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Oxidase aa(3) subunit 1; Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MVKLYPKTSLGMALVYISGAISWLIVMGIAALWFRTILLNPHTNPAVGYAISPLYYFLVTLHGMSAMYIIVEDLALGIFA
YALYKSGMSVVHFRTLTALFWVLNLAPIVTFAGGPITGWYMYPPLALQTQSWLNYHTDALIGMAYFFLFINSVAAILASL
FMFIDAIKTRPKEGKIPIFASYAMMFAGALIFLTEPALAAGELWYTLYFWANVPVNPLTWVVLFWFFGHPVVYYVPFTVF
GGLYALIPHYAGRPLYSERWARWNIILLFTFSMLAWVHHLQTFPLPVYIRAFITPTTLILAAGSGLTVLNLALTIFYSPT
GYNYKDPVGFAALIAYIGFILAGLQALILPINITNVIVHNTYYVVGHFHLMIWTIIIVGSVAIILDMLRNQVGAKLDFSS
LGRGFLFAGLSMWTVGALLTGYTMSYAGYLGLIRRWDAYPIKFLPFMDVMTYGAMIMGLSFVFIALPIVLTMIRVGIPIF
WTPTTGVTASPGITMNTQPPSSGTPSITKEVSTSDMNNKVTKLK

Sequences:

>Translated_524_residues
MVKLYPKTSLGMALVYISGAISWLIVMGIAALWFRTILLNPHTNPAVGYAISPLYYFLVTLHGMSAMYIIVEDLALGIFA
YALYKSGMSVVHFRTLTALFWVLNLAPIVTFAGGPITGWYMYPPLALQTQSWLNYHTDALIGMAYFFLFINSVAAILASL
FMFIDAIKTRPKEGKIPIFASYAMMFAGALIFLTEPALAAGELWYTLYFWANVPVNPLTWVVLFWFFGHPVVYYVPFTVF
GGLYALIPHYAGRPLYSERWARWNIILLFTFSMLAWVHHLQTFPLPVYIRAFITPTTLILAAGSGLTVLNLALTIFYSPT
GYNYKDPVGFAALIAYIGFILAGLQALILPINITNVIVHNTYYVVGHFHLMIWTIIIVGSVAIILDMLRNQVGAKLDFSS
LGRGFLFAGLSMWTVGALLTGYTMSYAGYLGLIRRWDAYPIKFLPFMDVMTYGAMIMGLSFVFIALPIVLTMIRVGIPIF
WTPTTGVTASPGITMNTQPPSSGTPSITKEVSTSDMNNKVTKLK
>Mature_524_residues
MVKLYPKTSLGMALVYISGAISWLIVMGIAALWFRTILLNPHTNPAVGYAISPLYYFLVTLHGMSAMYIIVEDLALGIFA
YALYKSGMSVVHFRTLTALFWVLNLAPIVTFAGGPITGWYMYPPLALQTQSWLNYHTDALIGMAYFFLFINSVAAILASL
FMFIDAIKTRPKEGKIPIFASYAMMFAGALIFLTEPALAAGELWYTLYFWANVPVNPLTWVVLFWFFGHPVVYYVPFTVF
GGLYALIPHYAGRPLYSERWARWNIILLFTFSMLAWVHHLQTFPLPVYIRAFITPTTLILAAGSGLTVLNLALTIFYSPT
GYNYKDPVGFAALIAYIGFILAGLQALILPINITNVIVHNTYYVVGHFHLMIWTIIIVGSVAIILDMLRNQVGAKLDFSS
LGRGFLFAGLSMWTVGALLTGYTMSYAGYLGLIRRWDAYPIKFLPFMDVMTYGAMIMGLSFVFIALPIVLTMIRVGIPIF
WTPTTGVTASPGITMNTQPPSSGTPSITKEVSTSDMNNKVTKLK

Specific function: Subunit I binds heme a and the bimetallic center [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=392, Percent_Identity=25.765306122449, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1786634, Length=333, Percent_Identity=24.024024024024, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6226519, Length=389, Percent_Identity=26.9922879177378, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6226524, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.9.3.-

Molecular weight: Translated: 58324; Mature: 58324

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLYPKTSLGMALVYISGAISWLIVMGIAALWFRTILLNPHTNPAVGYAISPLYYFLVT
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LHGMSAMYIIVEDLALGIFAYALYKSGMSVVHFRTLTALFWVLNLAPIVTFAGGPITGWY
HHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECEE
MYPPLALQTQSWLNYHTDALIGMAYFFLFINSVAAILASLFMFIDAIKTRPKEGKIPIFA
ECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
SYAMMFAGALIFLTEPALAAGELWYTLYFWANVPVNPLTWVVLFWFFGHPVVYYVPFTVF
HHHHHHHCHHHEEECCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHH
GGLYALIPHYAGRPLYSERWARWNIILLFTFSMLAWVHHLQTFPLPVYIRAFITPTTLIL
HHHHHHHHHHCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEE
AAGSGLTVLNLALTIFYSPTGYNYKDPVGFAALIAYIGFILAGLQALILPINITNVIVHN
ECCCCHHHHEEEEHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHEEEEEC
TYYVVGHFHLMIWTIIIVGSVAIILDMLRNQVGAKLDFSSLGRGFLFAGLSMWTVGALLT
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHH
GYTMSYAGYLGLIRRWDAYPIKFLPFMDVMTYGAMIMGLSFVFIALPIVLTMIRVGIPIF
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
WTPTTGVTASPGITMNTQPPSSGTPSITKEVSTSDMNNKVTKLK
ECCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKLYPKTSLGMALVYISGAISWLIVMGIAALWFRTILLNPHTNPAVGYAISPLYYFLVT
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LHGMSAMYIIVEDLALGIFAYALYKSGMSVVHFRTLTALFWVLNLAPIVTFAGGPITGWY
HHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECEE
MYPPLALQTQSWLNYHTDALIGMAYFFLFINSVAAILASLFMFIDAIKTRPKEGKIPIFA
ECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
SYAMMFAGALIFLTEPALAAGELWYTLYFWANVPVNPLTWVVLFWFFGHPVVYYVPFTVF
HHHHHHHCHHHEEECCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHH
GGLYALIPHYAGRPLYSERWARWNIILLFTFSMLAWVHHLQTFPLPVYIRAFITPTTLIL
HHHHHHHHHHCCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEE
AAGSGLTVLNLALTIFYSPTGYNYKDPVGFAALIAYIGFILAGLQALILPINITNVIVHN
ECCCCHHHHEEEEHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHEEEEEC
TYYVVGHFHLMIWTIIIVGSVAIILDMLRNQVGAKLDFSSLGRGFLFAGLSMWTVGALLT
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHH
GYTMSYAGYLGLIRRWDAYPIKFLPFMDVMTYGAMIMGLSFVFIALPIVLTMIRVGIPIF
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
WTPTTGVTASPGITMNTQPPSSGTPSITKEVSTSDMNNKVTKLK
ECCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1372250 [H]