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The map label for this gene is nudF [H]

Identifier: 15922479

GI number: 15922479

Start: 2151774

End: 2152301

Strand: Direct

Name: nudF [H]

Synonym: ST2154

Alternate gene names: 15922479

Gene position: 2151774-2152301 (Clockwise)

Preceding gene: 15922478

Following gene: 15922481

Centisome position: 79.85

GC content: 30.87

Gene sequence:

>528_bases
ATGAGAATTTTCTCCTCCCAAAAATTTGATGTCATTATAGATAAATTCCAATTACCAAATGGAAAAGAAATAGAAAAAGC
ATATGTTAAACATAGGGGATCAGTAGTCATAGTACCATTTATTGATAAAGAAAAAATTATAATGATCAAGCAATACAGAC
CAATTATAGGAAAATGGTTAATAGAATTACCAGCGGGAACAGTTGAGGAAAAAGAAAATGAAGAAGAAACAGCAAGGAGA
GAATTAGAAGAGGAAATTGGTTACAAACCCAATTTTATGAGTAAGATATTTTCCTTCTATGTATCACCTGGAGTAACTAC
AGAAATTATGCATGTTTATATAGCTAGAGATTTAGTAAAAACTTCTCAGAACCTAGAAGAATATGAGGTTATCGAACCCT
TCGAAATAAGATTTGAGGATGCAGTAAAAATGGTATTGGATGGAAAAATCGAGGATGGAAAAACAATGTTATCATTACTT
CTTATTTCACAAAAATATCGAGATCTCCTAACTCACCAACTAATATAG

Upstream 100 bases:

>100_bases
TTTTCTTTATAATAGGATTCTTACTCATAAAAATAGACTGGAACTCTTTATATGAGAAAATTAGTGAAAAATATTTAAAT
AAAAGAATATAGTAGTATCC

Downstream 100 bases:

>100_bases
GTTCCTCTAATGTAATCCACTTCCTAGCTTTTGCCTCTCTTAATTTTTCAACAACATTTGTCCACTTATAAAGATCAGGT
ATTTCATAAATTACTACAAA

Product: hypothetical protein

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MRIFSSQKFDVIIDKFQLPNGKEIEKAYVKHRGSVVIVPFIDKEKIIMIKQYRPIIGKWLIELPAGTVEEKENEEETARR
ELEEEIGYKPNFMSKIFSFYVSPGVTTEIMHVYIARDLVKTSQNLEEYEVIEPFEIRFEDAVKMVLDGKIEDGKTMLSLL
LISQKYRDLLTHQLI

Sequences:

>Translated_175_residues
MRIFSSQKFDVIIDKFQLPNGKEIEKAYVKHRGSVVIVPFIDKEKIIMIKQYRPIIGKWLIELPAGTVEEKENEEETARR
ELEEEIGYKPNFMSKIFSFYVSPGVTTEIMHVYIARDLVKTSQNLEEYEVIEPFEIRFEDAVKMVLDGKIEDGKTMLSLL
LISQKYRDLLTHQLI
>Mature_175_residues
MRIFSSQKFDVIIDKFQLPNGKEIEKAYVKHRGSVVIVPFIDKEKIIMIKQYRPIIGKWLIELPAGTVEEKENEEETARR
ELEEEIGYKPNFMSKIFSFYVSPGVTTEIMHVYIARDLVKTSQNLEEYEVIEPFEIRFEDAVKMVLDGKIEDGKTMLSLL
LISQKYRDLLTHQLI

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788810, Length=143, Percent_Identity=33.5664335664336, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 20517; Mature: 20517

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFSSQKFDVIIDKFQLPNGKEIEKAYVKHRGSVVIVPFIDKEKIIMIKQYRPIIGKWL
CCCCCCCCHHEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHH
IELPAGTVEEKENEEETARRELEEEIGYKPNFMSKIFSFYVSPGVTTEIMHVYIARDLVK
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TSQNLEEYEVIEPFEIRFEDAVKMVLDGKIEDGKTMLSLLLISQKYRDLLTHQLI
HHCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIFSSQKFDVIIDKFQLPNGKEIEKAYVKHRGSVVIVPFIDKEKIIMIKQYRPIIGKWL
CCCCCCCCHHEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHH
IELPAGTVEEKENEEETARRELEEEIGYKPNFMSKIFSFYVSPGVTTEIMHVYIARDLVK
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TSQNLEEYEVIEPFEIRFEDAVKMVLDGKIEDGKTMLSLLLISQKYRDLLTHQLI
HHCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]