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The map label for this gene is cutL [H]

Identifier: 15922093

GI number: 15922093

Start: 1798339

End: 1800573

Strand: Reverse

Name: cutL [H]

Synonym: ST1781

Alternate gene names: 15922093

Gene position: 1800573-1798339 (Counterclockwise)

Preceding gene: 15922094

Following gene: 15922090

Centisome position: 66.82

GC content: 38.3

Gene sequence:

>2235_bases
ATGAGGTATGTTGGTCAAGCAGTTAAAAGACTTTATGATGATAAGTTCGTAACCGGAAAAAGTACCTATGTGGATGATAT
TCAAATATCAGCACTATATGCCGGATTTGTAAGAAGTCCCTATTCACATGCTAAAATAAAGAGTATTGATGTTACAGACG
CGTTAAAAGTCCCCGGTATAGTTGCTGTATACACTTACAAGGATTTAGCACCGTTAATAAAAGACGGTATAAGAATTTGG
ACCACATATGAAGATCCGAGGATGTGGAAGTTTGTTCCCAGAAAGCCATTAGCAGATGGTAAAGTTAGATTTGCCGGTGA
GCCTGTAGCAATAGTTATTGGTGTAAATAAATATGTTGTTAGAGATGCTATTGATAAAGTGAACGTTGATTATGAGAAAT
TACCGCCAGTAGTAAAAATGGAAGAGGCTTTAGAAGATAAAGTAATAATCCACGAAGAGTTAAAAACTAATGTAGCCTTT
GATCAAACCTTTAATGGTGGAAATGTAGAAGAAGCTTTTAAGCAAGCAGATAAAGTTATCCCAGTTGAAATAACCAATAA
TAGATTAATTCCATCACCAATGGAACCGAGAGGTATAGTTTCACGCTATGAAGGCGGAACGTTAACAATATGGTATTCTA
CTCAAGTTCCTCATTTAGCTAGGAGTGAATTTGCGAGAATATTTGGAGTTCCAGCTAGTAAAATAAGAGTAATAATGCCA
GATGTTGGCGGAGCTTTTGGAAGCAAAGTTAACTTTATGCCAGAAGAAGTTAGCGTTATAGCATCCTCAATAAAGTTAGG
AAGAGCTGTAAGATGGACAGCTACCAGAAGCGAGGAAATGTTAGCATCAGAGGCCAGACATAATACGTTTAAGGGAGAAG
TAGCAGTAAAGAATGACGGTACGGTATTAGGTATAAGGGGAGACTTACTAGTTGATTTAGGTGCTTATTTAACGCTTACT
GCACCATTACAACCTGCAATAATCCCACTAATGGTACCTGGACCTTATAAGATTAAAGGCGTTAGTATAAGAAGTAGGGC
TGTTTATACTACTACACCACCAATTACGATGTATAGGGGTGCGAGTAGACCAGAGGCAACATTTATCATAGAGAGAATTA
TGAGTATTGTAGCCGATGAATTAAAGTTAGACGACGTAACTATTAGAGAGAGGAATTTGGTAAGGGCAAATGAAATGCCA
TATACAAATCCCTTTGGGCTGAAATACGATTCTGGTGATTACTTGGCTTTACTAAAGGATGGAATACAGAAACTTCAATA
CTATGAATTAAAGAAGTGGGCTGAAGAAGAGAGAAAGAAGGGAAGAAAAGTAGGAGTTGGTATGGCGTATTACCTGGAAA
TTAGTGGTTTTGGTCCTTGGGAATTTGGAGAAATCAGAGTCGATGAAAACGGTGATGTATTAGTTATCACTGGAGGAACT
CCTCACGGTCAAGGAACAGAAACGGCAATAGCACAAGTAGTTGCAGATACTTTACAAATAGACATTAGTAGAATAAAGGT
AATATGGGGAGATACAGAAACAGTAGTAGCAAGTATGGGAACTTATGGTTCAAGAACAGCTGCTGCTGCAGCTAGTGCGG
CTATGGTTGCTTCAAAGGAAGTATTAGAAAAAATGAAGAGAATTGCTGCTGGGTTATTAAATGCAGATGTAGAAGAAATT
GAGTATGAAAGTGGAGAATTCTATAATAAGAAAGATAAGAGTAAAAAAGTAAGTTGGAATGATGTAGCTAGAAACGGTTA
TTATGGTAAAGAGTTGGGAATATCAGCCCAAATAATCTTACCTGGTGATGTTACATTCCCGTATGGTGTTCATGTAGCGG
TTGTTGAAGTCGATGACTATGGTATTCCTAGAGTATTAACATACAAAGCATATGATGATATAGGTAATGTAATAAATCCG
GCGTTAGCTGAAGGTCAAATACACGGGGGTGGCGTGCAAGCTGTTGGACAAGCATTATATGAAGAGGCTATCATTAACGA
AGATGGACAACTCACTGTTACTTATGCTGATTACTTTATACCGACAGCTGTTGAAGCACCAAAGTTCGAGAGCTACTTCG
TTGAAAAACCTCACACATCAACATGGCCTACAGGTGCTAAAGGAGTAGGTGAAGCCGCATTAATAGTTGGACCAGCAGTA
ATTATCAGAGCATTAGAGGATGCAACAGGGAAGAGGTTTACAAAGACACCCGTTAGACCTGAAGAGATATTATGA

Upstream 100 bases:

>100_bases
AAGAGGAAATAAGAGATGGCTTACACGGTAATATTTGCAGATGTACTGGTTATCAAAACATAATAAAAGCTGTACAAGAT
GCTTCTAAGAGGATGAGAGC

Downstream 100 bases:

>100_bases
AAGTAAGTTAATATTTTTATTTTACCTTTATCATTTGCTCTAACAAAAATGAACAACAAGTTCTATCCTCAAGACGAAGT
AAAGTTTTTTGATCTTAGCT

Product: carbon-monoxide dehydrogenase large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MRYVGQAVKRLYDDKFVTGKSTYVDDIQISALYAGFVRSPYSHAKIKSIDVTDALKVPGIVAVYTYKDLAPLIKDGIRIW
TTYEDPRMWKFVPRKPLADGKVRFAGEPVAIVIGVNKYVVRDAIDKVNVDYEKLPPVVKMEEALEDKVIIHEELKTNVAF
DQTFNGGNVEEAFKQADKVIPVEITNNRLIPSPMEPRGIVSRYEGGTLTIWYSTQVPHLARSEFARIFGVPASKIRVIMP
DVGGAFGSKVNFMPEEVSVIASSIKLGRAVRWTATRSEEMLASEARHNTFKGEVAVKNDGTVLGIRGDLLVDLGAYLTLT
APLQPAIIPLMVPGPYKIKGVSIRSRAVYTTTPPITMYRGASRPEATFIIERIMSIVADELKLDDVTIRERNLVRANEMP
YTNPFGLKYDSGDYLALLKDGIQKLQYYELKKWAEEERKKGRKVGVGMAYYLEISGFGPWEFGEIRVDENGDVLVITGGT
PHGQGTETAIAQVVADTLQIDISRIKVIWGDTETVVASMGTYGSRTAAAAASAAMVASKEVLEKMKRIAAGLLNADVEEI
EYESGEFYNKKDKSKKVSWNDVARNGYYGKELGISAQIILPGDVTFPYGVHVAVVEVDDYGIPRVLTYKAYDDIGNVINP
ALAEGQIHGGGVQAVGQALYEEAIINEDGQLTVTYADYFIPTAVEAPKFESYFVEKPHTSTWPTGAKGVGEAALIVGPAV
IIRALEDATGKRFTKTPVRPEEIL

Sequences:

>Translated_744_residues
MRYVGQAVKRLYDDKFVTGKSTYVDDIQISALYAGFVRSPYSHAKIKSIDVTDALKVPGIVAVYTYKDLAPLIKDGIRIW
TTYEDPRMWKFVPRKPLADGKVRFAGEPVAIVIGVNKYVVRDAIDKVNVDYEKLPPVVKMEEALEDKVIIHEELKTNVAF
DQTFNGGNVEEAFKQADKVIPVEITNNRLIPSPMEPRGIVSRYEGGTLTIWYSTQVPHLARSEFARIFGVPASKIRVIMP
DVGGAFGSKVNFMPEEVSVIASSIKLGRAVRWTATRSEEMLASEARHNTFKGEVAVKNDGTVLGIRGDLLVDLGAYLTLT
APLQPAIIPLMVPGPYKIKGVSIRSRAVYTTTPPITMYRGASRPEATFIIERIMSIVADELKLDDVTIRERNLVRANEMP
YTNPFGLKYDSGDYLALLKDGIQKLQYYELKKWAEEERKKGRKVGVGMAYYLEISGFGPWEFGEIRVDENGDVLVITGGT
PHGQGTETAIAQVVADTLQIDISRIKVIWGDTETVVASMGTYGSRTAAAAASAAMVASKEVLEKMKRIAAGLLNADVEEI
EYESGEFYNKKDKSKKVSWNDVARNGYYGKELGISAQIILPGDVTFPYGVHVAVVEVDDYGIPRVLTYKAYDDIGNVINP
ALAEGQIHGGGVQAVGQALYEEAIINEDGQLTVTYADYFIPTAVEAPKFESYFVEKPHTSTWPTGAKGVGEAALIVGPAV
IIRALEDATGKRFTKTPVRPEEIL
>Mature_744_residues
MRYVGQAVKRLYDDKFVTGKSTYVDDIQISALYAGFVRSPYSHAKIKSIDVTDALKVPGIVAVYTYKDLAPLIKDGIRIW
TTYEDPRMWKFVPRKPLADGKVRFAGEPVAIVIGVNKYVVRDAIDKVNVDYEKLPPVVKMEEALEDKVIIHEELKTNVAF
DQTFNGGNVEEAFKQADKVIPVEITNNRLIPSPMEPRGIVSRYEGGTLTIWYSTQVPHLARSEFARIFGVPASKIRVIMP
DVGGAFGSKVNFMPEEVSVIASSIKLGRAVRWTATRSEEMLASEARHNTFKGEVAVKNDGTVLGIRGDLLVDLGAYLTLT
APLQPAIIPLMVPGPYKIKGVSIRSRAVYTTTPPITMYRGASRPEATFIIERIMSIVADELKLDDVTIRERNLVRANEMP
YTNPFGLKYDSGDYLALLKDGIQKLQYYELKKWAEEERKKGRKVGVGMAYYLEISGFGPWEFGEIRVDENGDVLVITGGT
PHGQGTETAIAQVVADTLQIDISRIKVIWGDTETVVASMGTYGSRTAAAAASAAMVASKEVLEKMKRIAAGLLNADVEEI
EYESGEFYNKKDKSKKVSWNDVARNGYYGKELGISAQIILPGDVTFPYGVHVAVVEVDDYGIPRVLTYKAYDDIGNVINP
ALAEGQIHGGGVQAVGQALYEEAIINEDGQLTVTYADYFIPTAVEAPKFESYFVEKPHTSTWPTGAKGVGEAALIVGPAV
IIRALEDATGKRFTKTPVRPEEIL

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=788, Percent_Identity=26.5228426395939, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI91823271, Length=759, Percent_Identity=26.4822134387352, Blast_Score=183, Evalue=7e-46,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=29.8684210526316, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1789246, Length=802, Percent_Identity=26.9326683291771, Blast_Score=245, Evalue=8e-66,
Organism=Escherichia coli, GI1786478, Length=768, Percent_Identity=23.046875, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=782, Percent_Identity=24.4245524296675, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17539860, Length=770, Percent_Identity=23.5064935064935, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32566215, Length=509, Percent_Identity=25.7367387033399, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17737937, Length=728, Percent_Identity=25.4120879120879, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24647199, Length=764, Percent_Identity=25.6544502617801, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24647193, Length=681, Percent_Identity=24.9632892804699, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24647201, Length=746, Percent_Identity=24.2627345844504, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647195, Length=769, Percent_Identity=22.2366710013004, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24647197, Length=756, Percent_Identity=22.0899470899471, Blast_Score=97, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81948; Mature: 81948

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVGQAVKRLYDDKFVTGKSTYVDDIQISALYAGFVRSPYSHAKIKSIDVTDALKVPGI
CCHHHHHHHHHHCCCEECCCCCEECCEEEHHHHHHHHCCCCCCCEEEEECCHHHHCCCCE
VAVYTYKDLAPLIKDGIRIWTTYEDPRMWKFVPRKPLADGKVRFAGEPVAIVIGVNKYVV
EEEEEHHHHHHHHHCCEEEEEEECCCCEEEECCCCCCCCCEEEECCCCEEEEEECCHHHH
RDAIDKVNVDYEKLPPVVKMEEALEDKVIIHEELKTNVAFDQTFNGGNVEEAFKQADKVI
HHHHHHCCCCHHHCCCHHHHHHHHCCCEEEEHHHHCCEEEECCCCCCCHHHHHHHHCCEE
PVEITNNRLIPSPMEPRGIVSRYEGGTLTIWYSTQVPHLARSEFARIFGVPASKIRVIMP
EEEECCCEECCCCCCCCCHHEECCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEEEC
DVGGAFGSKVNFMPEEVSVIASSIKLGRAVRWTATRSEEMLASEARHNTFKGEVAVKNDG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCC
TVLGIRGDLLVDLGAYLTLTAPLQPAIIPLMVPGPYKIKGVSIRSRAVYTTTPPITMYRG
EEEEECCCCEEECCCEEEEECCCCCCEEEEECCCCEEEEEEEEECCEEEECCCCEEEECC
ASRPEATFIIERIMSIVADELKLDDVTIRERNLVRANEMPYTNPFGLKYDSGDYLALLKD
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCEEECCCCCHHHHHH
GIQKLQYYELKKWAEEERKKGRKVGVGMAYYLEISGFGPWEFGEIRVDENGDVLVITGGT
HHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCEEEEECCC
PHGQGTETAIAQVVADTLQIDISRIKVIWGDTETVVASMGTYGSRTAAAAASAAMVASKE
CCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VLEKMKRIAAGLLNADVEEIEYESGEFYNKKDKSKKVSWNDVARNGYYGKELGISAQIIL
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEE
PGDVTFPYGVHVAVVEVDDYGIPRVLTYKAYDDIGNVINPALAEGQIHGGGVQAVGQALY
CCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHHHHHCCHHHCCCCCCCCHHHHHHHHH
EEAIINEDGQLTVTYADYFIPTAVEAPKFESYFVEKPHTSTWPTGAKGVGEAALIVGPAV
HHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHHH
IIRALEDATGKRFTKTPVRPEEIL
HHHHHHHCCCCCEECCCCCHHHCC
>Mature Secondary Structure
MRYVGQAVKRLYDDKFVTGKSTYVDDIQISALYAGFVRSPYSHAKIKSIDVTDALKVPGI
CCHHHHHHHHHHCCCEECCCCCEECCEEEHHHHHHHHCCCCCCCEEEEECCHHHHCCCCE
VAVYTYKDLAPLIKDGIRIWTTYEDPRMWKFVPRKPLADGKVRFAGEPVAIVIGVNKYVV
EEEEEHHHHHHHHHCCEEEEEEECCCCEEEECCCCCCCCCEEEECCCCEEEEEECCHHHH
RDAIDKVNVDYEKLPPVVKMEEALEDKVIIHEELKTNVAFDQTFNGGNVEEAFKQADKVI
HHHHHHCCCCHHHCCCHHHHHHHHCCCEEEEHHHHCCEEEECCCCCCCHHHHHHHHCCEE
PVEITNNRLIPSPMEPRGIVSRYEGGTLTIWYSTQVPHLARSEFARIFGVPASKIRVIMP
EEEECCCEECCCCCCCCCHHEECCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEEEC
DVGGAFGSKVNFMPEEVSVIASSIKLGRAVRWTATRSEEMLASEARHNTFKGEVAVKNDG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCC
TVLGIRGDLLVDLGAYLTLTAPLQPAIIPLMVPGPYKIKGVSIRSRAVYTTTPPITMYRG
EEEEECCCCEEECCCEEEEECCCCCCEEEEECCCCEEEEEEEEECCEEEECCCCEEEECC
ASRPEATFIIERIMSIVADELKLDDVTIRERNLVRANEMPYTNPFGLKYDSGDYLALLKD
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCEEECCCCCHHHHHH
GIQKLQYYELKKWAEEERKKGRKVGVGMAYYLEISGFGPWEFGEIRVDENGDVLVITGGT
HHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCEEEECCCCCEEEEECCC
PHGQGTETAIAQVVADTLQIDISRIKVIWGDTETVVASMGTYGSRTAAAAASAAMVASKE
CCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VLEKMKRIAAGLLNADVEEIEYESGEFYNKKDKSKKVSWNDVARNGYYGKELGISAQIIL
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEE
PGDVTFPYGVHVAVVEVDDYGIPRVLTYKAYDDIGNVINPALAEGQIHGGGVQAVGQALY
CCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHHHHHCCHHHCCCCCCCCHHHHHHHHH
EEAIINEDGQLTVTYADYFIPTAVEAPKFESYFVEKPHTSTWPTGAKGVGEAALIVGPAV
HHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEHHHH
IIRALEDATGKRFTKTPVRPEEIL
HHHHHHHCCCCCEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]