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The map label for this gene is purQ [H]

Identifier: 15921788

GI number: 15921788

Start: 1488957

End: 1489409

Strand: Direct

Name: purQ [H]

Synonym: ST1494

Alternate gene names: 15921788

Gene position: 1488957-1489409 (Clockwise)

Preceding gene: 15921787

Following gene: 15921789

Centisome position: 55.25

GC content: 34.22

Gene sequence:

>453_bases
ATGGCGGATGAGGGTAAAATTGTAATCGGAATATGCAACGGATTTCAAATATTGGTTGAAAGTGGTCTCTTAGAAGGTGC
TCTTTTACCTAACTTAAATTTGCGTTTTATCAGTAAGTGGGTTTACTTGAGAGTCGTTAGATTTGATACAGCTGTAACTC
GTGGATTAAATAAGACTATTCTAAAAATGCCTATAGCACATGCAGAAGGGAGATTTTATTTAGATAATGTAGAGAAAGCA
AAGAAATATGCTGTTATGTTATATTGTGACGAAAATGGTAATGTGAACGATATGGTAAATCCTAATGGTTCAATTCTCAA
TATAGCTTCAATTGCTAATGAAGAAGGAAATGTCATAGGCATGATGCCACATCCAGAGAGGGCATCTTTCAAATTAACCT
CTATAACGGGTGAAACTGATGGATTATTATTATTTAAGGGGTTAAGAAAATGA

Upstream 100 bases:

>100_bases
GTATAGTGCAGTTATTTTGCCAGGAGGTTTTAGTTTTGGTGATTATCTTAGAGCTGGTAGTATTGCCGCTAGTACGGAAA
CAATTAAGAAAGTTAAAGAA

Downstream 100 bases:

>100_bases
AAATAACACTTTCTTCGTACGAAATGGAACTAGTAAGAAAGAAGCTTGCAAGAGAACCTAATGAGGCTGAATGGCTAACT
ATAGATGCATTATGGAGTGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MADEGKIVIGICNGFQILVESGLLEGALLPNLNLRFISKWVYLRVVRFDTAVTRGLNKTILKMPIAHAEGRFYLDNVEKA
KKYAVMLYCDENGNVNDMVNPNGSILNIASIANEEGNVIGMMPHPERASFKLTSITGETDGLLLFKGLRK

Sequences:

>Translated_150_residues
MADEGKIVIGICNGFQILVESGLLEGALLPNLNLRFISKWVYLRVVRFDTAVTRGLNKTILKMPIAHAEGRFYLDNVEKA
KKYAVMLYCDENGNVNDMVNPNGSILNIASIANEEGNVIGMMPHPERASFKLTSITGETDGLLLFKGLRK
>Mature_149_residues
ADEGKIVIGICNGFQILVESGLLEGALLPNLNLRFISKWVYLRVVRFDTAVTRGLNKTILKMPIAHAEGRFYLDNVEKAK
KYAVMLYCDENGNVNDMVNPNGSILNIASIANEEGNVIGMMPHPERASFKLTSITGETDGLLLFKGLRK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=147, Percent_Identity=29.9319727891156, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24582111, Length=139, Percent_Identity=28.0575539568345, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582109, Length=139, Percent_Identity=28.0575539568345, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17137292, Length=139, Percent_Identity=28.0575539568345, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 16586; Mature: 16454

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEGKIVIGICNGFQILVESGLLEGALLPNLNLRFISKWVYLRVVRFDTAVTRGLNKTI
CCCCCCEEEEEECCEEEEECCCCCCCEECCCCCHHHHHHEEEEEEEEHHHHHHCCCCCCE
LKMPIAHAEGRFYLDNVEKAKKYAVMLYCDENGNVNDMVNPNGSILNIASIANEEGNVIG
EECCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCEECCCCCEEEEEEECCCCCCEEE
MMPHPERASFKLTSITGETDGLLLFKGLRK
ECCCCCCCEEEEEEECCCCCCEEEEEECCC
>Mature Secondary Structure 
ADEGKIVIGICNGFQILVESGLLEGALLPNLNLRFISKWVYLRVVRFDTAVTRGLNKTI
CCCCCEEEEEECCEEEEECCCCCCCEECCCCCHHHHHHEEEEEEEEHHHHHHCCCCCCE
LKMPIAHAEGRFYLDNVEKAKKYAVMLYCDENGNVNDMVNPNGSILNIASIANEEGNVIG
EECCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCEECCCCCEEEEEEECCCCCCEEE
MMPHPERASFKLTSITGETDGLLLFKGLRK
ECCCCCCCEEEEEEECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]