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The map label for this gene is atpI [H]

Identifier: 15921722

GI number: 15921722

Start: 1436999

End: 1439104

Strand: Reverse

Name: atpI [H]

Synonym: ST1433

Alternate gene names: 15921722

Gene position: 1439104-1436999 (Counterclockwise)

Preceding gene: 15921735

Following gene: 15921720

Centisome position: 53.4

GC content: 32.15

Gene sequence:

>2106_bases
GTGATTATTCCCGAGACAATGGCTAGAGTGGAAATACTGACACCGAAACAAAAAATAAATGAACTCATAACAGCTCTCTT
AAAATTCAAAGAATTCGAACCCGAAGAGCCAAAAACACCAATATCAAACCTTAGATTTGAGGATGCAAGACGAAATCTAG
GTGAAGTAAACGAGCACATAAACAAAATGAAGATTTTAATGGAATTGGGCGGATTAATTATAGAACCTCAAGGTAAAATG
AAAGTAAATGACTGGATAGAGGCATCTAATCAAGTATTTATCGAGGGCTCAGAAATAGAGAATAAATATAAAGATTTACT
AGAGGAAATAGGAAAATTAAGGGCAGAATTAGATACTCTAAATTCACAACTACAGGAAGTAGAACCATTTAAAAATATTG
GAATTGATCTTAAGGTTCTATATTCCTCTACAAATTTTGAAGTAGCATTAGTAGTTATTAATGAAATACAGAAAAAACAA
CTAGAAGATAAAGGAGCAGTAGTTATAGTAGAGGAATTAGGAAATAATAAATATGCCAGCCTAGTACTTTCAAGAAAAGG
CTCAAACTTAGACGAAATACTAAAAGAACTTGGACTTAGAAAATTTGAAACACCTGATTTTATTGCACCACAAATTTACT
ACAGTAACTTGAAAGAAAGAATTAATAATATACAAACTATACTAACTCAAAGAAGAGAAGAATTAGCTAAGAAAATTAAA
GAAGATGAGAAAAATGTTAAAGAACTTTATGGAAAATTACTCACAATTAGAGATGCAATGAATATTCTCGCAAAAGCAAG
AAAATCTGAGTATTACGTTCAAGTTGAAGGTTATGTACCAGATAAATCACTAAAAAAACTGTCTAAGATGATAGAAAATA
TCGGGTTTATAACTTATGAGTATCCGAAAAGATACGGAGAAGAACAAGAAGAACCACCTACTTATGTTAAATTACCAAAA
TCAATTATTCCGTTAGAATCCGTAATAGAATTTTATGGAACACCTTCTTATTGGGAAATTTCGCCAACAATATTCCTTAT
TATAACATTTCCCTTCCTTTTTGGTCTAATGTTCCCAGATTTTGGAAACGCACTTGTTCTTTTACTCTTTTCTATATGGT
TTTACAATTACGGTAAAAAGAGAGGAAGCGAGAATACAGTAAAACTCTCATTAGTTCTTATATACTCAAGTATAGTTGCA
ATGGTTACCGGTCTTCTAGCTAGAGAATTCTTTGGTCCTTTACCAGTAGGAGGTTTACAAGAATTACTAAATAACCCGTC
TGCACCAGTTGGCCCGTTATATTATGCTTGGCCCATTCCAGTTTCATTTTATGAAAAGATAAGTGATATAATTCCTACTG
GTGCAAACGCAATAATTAATACAATATTATTATCATTACTACTGGGATCTATATTACTATTCGTAAGTACACTACTTGGA
GTTATAAATGCTATAAAGAAAAAAGATAAAGAATTTCTATTCTTAGATAGGTTACCATTATTTATTATATATATAGTACC
TCTAATAGTTTTCCTATATGGATTCATTAACATCAGCAATTATCAAGGAGAAGAGGCAATGATATTAGGAGGAATTTCAT
ATTTCCTATTCCATTCAGGTACGCCAGCACCTCCAAGTGTACAAATTTTAGCTGACATCTTGGTAATATGGGTAGAGATA
GGACTAATATACAATTGGGTTGCAAAAGCGTATCTTTTAAAGAAGCATGAGCATGCTAGCACTGGTTCAGCAATAATATT
TGGCTTTATTGAAGGAGGTTTTGAGGCAGCTTTACTGTTGCTATCAAATACAATATCATTCATACGTGTACTAGTTTTTG
CAATAGCACACTATTACATCCTTTATGCATTCTCTTATATGGCTTACTTGGCTGCAGGAAATCCTTCATCGTTATTGTCA
GTTTTCATAAACCCAGCTGGTATAGTCATATTAATTATAGGCAATTTACTGGCAATAGCCTTAGAAGGATTAATAGTATT
TATCCAAGATATGAGACTTCACTTCTACGAAATGTTTAGTAAATTCTATGAGGGAAGAGGAAGAAAATTCGAACCAGTAA
TGACTTATGTTGAGTTAACGCAATAA

Upstream 100 bases:

>100_bases
CTTGTCCCCAATAACTAAAACTTTACCCATCTCGAACTATCATTTTAAATTTAAGATTAAATATTTTTAACCTATCCGTA
ATTTAACATAATGAATCACA

Downstream 100 bases:

>100_bases
GGTAGGTCTTATTTTTTCTAAGTTCTTTCTTATTTCATCTAATTTTTTATTTATATCATTCTCATTTAGTTCGACTTTTT
TAAACAGAACGCTTACCTCA

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MIIPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPISNLRFEDARRNLGEVNEHINKMKILMELGGLIIEPQGKM
KVNDWIEASNQVFIEGSEIENKYKDLLEEIGKLRAELDTLNSQLQEVEPFKNIGIDLKVLYSSTNFEVALVVINEIQKKQ
LEDKGAVVIVEELGNNKYASLVLSRKGSNLDEILKELGLRKFETPDFIAPQIYYSNLKERINNIQTILTQRREELAKKIK
EDEKNVKELYGKLLTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIGFITYEYPKRYGEEQEEPPTYVKLPK
SIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPDFGNALVLLLFSIWFYNYGKKRGSENTVKLSLVLIYSSIVA
MVTGLLAREFFGPLPVGGLQELLNNPSAPVGPLYYAWPIPVSFYEKISDIIPTGANAIINTILLSLLLGSILLFVSTLLG
VINAIKKKDKEFLFLDRLPLFIIYIVPLIVFLYGFINISNYQGEEAMILGGISYFLFHSGTPAPPSVQILADILVIWVEI
GLIYNWVAKAYLLKKHEHASTGSAIIFGFIEGGFEAALLLLSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNPSSLLS
VFINPAGIVILIIGNLLAIALEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVELTQ

Sequences:

>Translated_701_residues
MIIPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPISNLRFEDARRNLGEVNEHINKMKILMELGGLIIEPQGKM
KVNDWIEASNQVFIEGSEIENKYKDLLEEIGKLRAELDTLNSQLQEVEPFKNIGIDLKVLYSSTNFEVALVVINEIQKKQ
LEDKGAVVIVEELGNNKYASLVLSRKGSNLDEILKELGLRKFETPDFIAPQIYYSNLKERINNIQTILTQRREELAKKIK
EDEKNVKELYGKLLTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIGFITYEYPKRYGEEQEEPPTYVKLPK
SIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPDFGNALVLLLFSIWFYNYGKKRGSENTVKLSLVLIYSSIVA
MVTGLLAREFFGPLPVGGLQELLNNPSAPVGPLYYAWPIPVSFYEKISDIIPTGANAIINTILLSLLLGSILLFVSTLLG
VINAIKKKDKEFLFLDRLPLFIIYIVPLIVFLYGFINISNYQGEEAMILGGISYFLFHSGTPAPPSVQILADILVIWVEI
GLIYNWVAKAYLLKKHEHASTGSAIIFGFIEGGFEAALLLLSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNPSSLLS
VFINPAGIVILIIGNLLAIALEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVELTQ
>Mature_701_residues
MIIPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPISNLRFEDARRNLGEVNEHINKMKILMELGGLIIEPQGKM
KVNDWIEASNQVFIEGSEIENKYKDLLEEIGKLRAELDTLNSQLQEVEPFKNIGIDLKVLYSSTNFEVALVVINEIQKKQ
LEDKGAVVIVEELGNNKYASLVLSRKGSNLDEILKELGLRKFETPDFIAPQIYYSNLKERINNIQTILTQRREELAKKIK
EDEKNVKELYGKLLTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIGFITYEYPKRYGEEQEEPPTYVKLPK
SIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPDFGNALVLLLFSIWFYNYGKKRGSENTVKLSLVLIYSSIVA
MVTGLLAREFFGPLPVGGLQELLNNPSAPVGPLYYAWPIPVSFYEKISDIIPTGANAIINTILLSLLLGSILLFVSTLLG
VINAIKKKDKEFLFLDRLPLFIIYIVPLIVFLYGFINISNYQGEEAMILGGISYFLFHSGTPAPPSVQILADILVIWVEI
GLIYNWVAKAYLLKKHEHASTGSAIIFGFIEGGFEAALLLLSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNPSSLLS
VFINPAGIVILIIGNLLAIALEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVELTQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI85386547, Length=571, Percent_Identity=22.0665499124343, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI85386056, Length=571, Percent_Identity=22.0665499124343, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI85386053, Length=571, Percent_Identity=22.0665499124343, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194097401, Length=572, Percent_Identity=22.9020979020979, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI19913418, Length=572, Percent_Identity=22.9020979020979, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI194097403, Length=578, Percent_Identity=23.0103806228374, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI42741679, Length=621, Percent_Identity=21.5780998389694, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542706, Length=181, Percent_Identity=27.0718232044199, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323699, Length=220, Percent_Identity=24.5454545454545, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24647955, Length=571, Percent_Identity=22.0665499124343, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357019, Length=571, Percent_Identity=22.0665499124343, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357061, Length=365, Percent_Identity=22.4657534246575, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24583722, Length=160, Percent_Identity=26.25, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24650959, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650961, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551995, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650967, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650965, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358171, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650956, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650963, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362794, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362792, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 79615; Mature: 79615

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPISNLRFEDARRNLGEVNEHI
CCCCHHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
NKMKILMELGGLIIEPQGKMKVNDWIEASNQVFIEGSEIENKYKDLLEEIGKLRAELDTL
HHHHHHHHHCCEEECCCCCEEHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
NSQLQEVEPFKNIGIDLKVLYSSTNFEVALVVINEIQKKQLEDKGAVVIVEELGNNKYAS
HHHHHHHCHHHHCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCCEEEEEECCCCCEEH
LVLSRKGSNLDEILKELGLRKFETPDFIAPQIYYSNLKERINNIQTILTQRREELAKKIK
EEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDEKNVKELYGKLLTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIGFITYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
YPKRYGEEQEEPPTYVKLPKSIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPD
CHHHCCCCCCCCCCEEECCHHHCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCC
FGNALVLLLFSIWFYNYGKKRGSENTVKLSLVLIYSSIVAMVTGLLAREFFGPLPVGGLQ
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ELLNNPSAPVGPLYYAWPIPVSFYEKISDIIPTGANAIINTILLSLLLGSILLFVSTLLG
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VINAIKKKDKEFLFLDRLPLFIIYIVPLIVFLYGFINISNYQGEEAMILGGISYFLFHSG
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHEECC
TPAPPSVQILADILVIWVEIGLIYNWVAKAYLLKKHEHASTGSAIIFGFIEGGFEAALLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHH
LSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNPSSLLSVFINPAGIVILIIGNLLAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVELTQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECC
>Mature Secondary Structure
MIIPETMARVEILTPKQKINELITALLKFKEFEPEEPKTPISNLRFEDARRNLGEVNEHI
CCCCHHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHH
NKMKILMELGGLIIEPQGKMKVNDWIEASNQVFIEGSEIENKYKDLLEEIGKLRAELDTL
HHHHHHHHHCCEEECCCCCEEHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
NSQLQEVEPFKNIGIDLKVLYSSTNFEVALVVINEIQKKQLEDKGAVVIVEELGNNKYAS
HHHHHHHCHHHHCCCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCCEEEEEECCCCCEEH
LVLSRKGSNLDEILKELGLRKFETPDFIAPQIYYSNLKERINNIQTILTQRREELAKKIK
EEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDEKNVKELYGKLLTIRDAMNILAKARKSEYYVQVEGYVPDKSLKKLSKMIENIGFITYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
YPKRYGEEQEEPPTYVKLPKSIIPLESVIEFYGTPSYWEISPTIFLIITFPFLFGLMFPD
CHHHCCCCCCCCCCEEECCHHHCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCC
FGNALVLLLFSIWFYNYGKKRGSENTVKLSLVLIYSSIVAMVTGLLAREFFGPLPVGGLQ
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ELLNNPSAPVGPLYYAWPIPVSFYEKISDIIPTGANAIINTILLSLLLGSILLFVSTLLG
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VINAIKKKDKEFLFLDRLPLFIIYIVPLIVFLYGFINISNYQGEEAMILGGISYFLFHSG
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHEECC
TPAPPSVQILADILVIWVEIGLIYNWVAKAYLLKKHEHASTGSAIIFGFIEGGFEAALLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHH
LSNTISFIRVLVFAIAHYYILYAFSYMAYLAAGNPSSLLSVFINPAGIVILIIGNLLAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LEGLIVFIQDMRLHFYEMFSKFYEGRGRKFEPVMTYVELTQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]