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The map label for this gene is trpG [H]

Identifier: 15921491

GI number: 15921491

Start: 1229605

End: 1230186

Strand: Reverse

Name: trpG [H]

Synonym: ST1228

Alternate gene names: 15921491

Gene position: 1230186-1229605 (Counterclockwise)

Preceding gene: 15921492

Following gene: 15921490

Centisome position: 45.65

GC content: 31.62

Gene sequence:

>582_bases
ATGGATTTAACGCTCATCATAGATAACTATGATAGTTTTGTATATAATATTGCTCAAATAGTAGGAGAATTAGGAAGCTA
TCCTATAGTTATAAGGAACGATGAGATTACAGTAAAAGGAGTTGAGAGAATAAATCCAGATAGAATAATAATTTCCCCAG
GTCCCGGAACTCCAGAAAAAAAGGAGGATATAGGGATAGTTATTGATGTTATCAAACAATTTGGTAGGAGAATTCCTATT
TTAGGAATTTGTTTAGGTCATCAAGCTATAGGATATGCATTTGGAGCAAAAATTAGGAAGGCCAGAAGAGTATTTCACGG
TAAAATAAGTAAAATAAATATAATTAACAACGTAGCATTATATGATGGTCTGCCGAAACAAATTGAAGCAACTAGATATC
ATAGTCTAGTTATAGATGATGTTAAAGAACCTCTAATAATTGATGCTTATTCCCTAGAAGATAATGAGATCATGGCTATT
CATCACTCAGAATTAAGAATTTATGGCGTTCAATTTCATCCAGAGAGTGTAGGAACACCATTAGGAAAGAGAATTATTTA
TAACTTTCTCAATAAAGTATAA

Upstream 100 bases:

>100_bases
AGCCGGTGCTGGTATAGTTTATGACTCAATACCGGAAATGGAATATTATGAGACTGAACATAAAATGAGAGCCTTAAAAG
TTGCTATGGGGGTAGTTTAG

Downstream 100 bases:

>100_bases
TTGAATGCCCAGGTATTTGGAAGGATGGTTAGCTGATGTTGTTAAAATCTCCTTAAACAGAGAAAGAATAAATAAGGTTA
GAGAAAGACCTATTTATTTA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEITVKGVERINPDRIIISPGPGTPEKKEDIGIVIDVIKQFGRRIPI
LGICLGHQAIGYAFGAKIRKARRVFHGKISKINIINNVALYDGLPKQIEATRYHSLVIDDVKEPLIIDAYSLEDNEIMAI
HHSELRIYGVQFHPESVGTPLGKRIIYNFLNKV

Sequences:

>Translated_193_residues
MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEITVKGVERINPDRIIISPGPGTPEKKEDIGIVIDVIKQFGRRIPI
LGICLGHQAIGYAFGAKIRKARRVFHGKISKINIINNVALYDGLPKQIEATRYHSLVIDDVKEPLIIDAYSLEDNEIMAI
HHSELRIYGVQFHPESVGTPLGKRIIYNFLNKV
>Mature_193_residues
MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEITVKGVERINPDRIIISPGPGTPEKKEDIGIVIDVIKQFGRRIPI
LGICLGHQAIGYAFGAKIRKARRVFHGKISKINIINNVALYDGLPKQIEATRYHSLVIDDVKEPLIIDAYSLEDNEIMAI
HHSELRIYGVQFHPESVGTPLGKRIIYNFLNKV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=44.7916666666667, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=36.3157894736842, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI1786215, Length=150, Percent_Identity=30, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=40.9574468085106, Blast_Score=145, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=30.4761904761905, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281365319, Length=145, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21717; Mature: 21717

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEITVKGVERINPDRIIISPGPGTPEK
CCEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCEEEEECCCCCCCC
KEDIGIVIDVIKQFGRRIPILGICLGHQAIGYAFGAKIRKARRVFHGKISKINIINNVAL
CCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHH
YDGLPKQIEATRYHSLVIDDVKEPLIIDAYSLEDNEIMAIHHSELRIYGVQFHPESVGTP
HCCCCHHHHHHHHHHEEECCCCCCEEEEEEECCCCCEEEEEECCEEEEEEEECCHHHCCC
LGKRIIYNFLNKV
HHHHHHHHHHHCC
>Mature Secondary Structure
MDLTLIIDNYDSFVYNIAQIVGELGSYPIVIRNDEITVKGVERINPDRIIISPGPGTPEK
CCEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCEEEEECCCCCCCC
KEDIGIVIDVIKQFGRRIPILGICLGHQAIGYAFGAKIRKARRVFHGKISKINIINNVAL
CCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHH
YDGLPKQIEATRYHSLVIDDVKEPLIIDAYSLEDNEIMAIHHSELRIYGVQFHPESVGTP
HCCCCHHHHHHHHHHEEECCCCCCEEEEEEECCCCCEEEEEECCEEEEEEEECCHHHCCC
LGKRIIYNFLNKV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8416906; 11427726; 10449718 [H]