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The map label for this gene is 15921481

Identifier: 15921481

GI number: 15921481

Start: 1219530

End: 1220648

Strand: Reverse

Name: 15921481

Synonym: ST1217

Alternate gene names: NA

Gene position: 1220648-1219530 (Counterclockwise)

Preceding gene: 15921482

Following gene: 15921480

Centisome position: 45.3

GC content: 34.41

Gene sequence:

>1119_bases
ATGCTTTTAATTCCTGGACCAGTTGAAGTACCAAGAAGCGTAAGAGAAGCCTCAACATTAGTAGTTAATCACAGAAGTGA
AAAATTTAGAGAGATAGTAAGAAAATTGGAAAGTTTAATGAATAAGCATTTTAGTGCGAGCAGGACTGCTTTACTTACGG
GATCGGGTACTTTAGCTGTTGAAGCAATGGTATATTCGTTGATTAAACCTAACGAAAAAGTAATTAGTTTTCCTTACGGT
GAATTTGGCAATAGGCTAGTGGACTCTTTGAGAAGAAGAGGAGCTCAAGTAAAAGTGTATGAGAAAAAGATTGGCGAAAT
TTTCTCTATAGATGAAATAAAGAAAGCATTAGATGAAAATAAAGATGCGACTGCAGTAGCTTTAGTTCATAATGAAACTA
GTTCTGGAATGGCATTTAGAAATTTAGAAGATGTAGTAAGTGAAGTAAAGAGAAGAGGATTAAAATTATTAGTAGACTCT
GTATCCGGTTTTGCTGCTTATAAATTATTAGTAAATGAATGGAAAATAGATGCAGTAGCTACTGGTAGTCAGAAAGCTCT
TGCCTCTGTACCAGGAATGTCATTTGTGGCTTTATCGGATGACGGTATTGAGGAAATACAAGGAGAGTCACTTCCTTCAT
ATCTTGATATTTCTCTCCATCTTAAGTTCCAGGATAAAGGAGAAACTCCATTTACTCCAGCTGTTGGCGTGTTTAATGCA
TCTTTAAGAGCAGCAGAATTATTAGAGATCGAAGGCATAGAAAATAGATGGAAAAGGCATGAGGCTTGCGCAAGATTTGT
AAGGGAAGTACTATCTTCTTATGGTTTCTTACTTTTTGGAAATGAAAATAATTTTTCAAATACTGTAGTTGCAGGTGTAC
CACCGATTCCAGATTATAGAAAGAAATTACTAAATGAATTTAATATTGAAATATCTGGAGGAATGGGAGAATTAAAGGAA
AAGATAGTAAGAATTGGATTGCTAGGAGTTGTTGATAGTAGAGCTGTAAATAAATTATTGGAGGCTACTGCCAAGTTATT
AGATAAAAATTATGACTATTTACCTCCAAGAGAATGTAAGCTTCCAGAATTACTAGAAAAAGAAGTTGAATGGAGTTAA

Upstream 100 bases:

>100_bases
ACTCATATTGGTGCTCAAACCAAAGAGGCTCAAAAAAGGGTAGCAGAAATGACTACTCAAAACTTGCTTAACGCTATGAA
AGAGTTAGGGATGATATAAA

Downstream 100 bases:

>100_bases
TCTTATTTAAATCTTTAGGGAGTGTTTAAGTGTGAGTATAAATAAAATTTTTGAGGAGAGCTGGAAAAACAGATTAACGA
AATACGAGATAGCTAGAATT

Product: serine--pyruvate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLLIPGPVEVPRSVREASTLVVNHRSEKFREIVRKLESLMNKHFSASRTALLTGSGTLAVEAMVYSLIKPNEKVISFPYG
EFGNRLVDSLRRRGAQVKVYEKKIGEIFSIDEIKKALDENKDATAVALVHNETSSGMAFRNLEDVVSEVKRRGLKLLVDS
VSGFAAYKLLVNEWKIDAVATGSQKALASVPGMSFVALSDDGIEEIQGESLPSYLDISLHLKFQDKGETPFTPAVGVFNA
SLRAAELLEIEGIENRWKRHEACARFVREVLSSYGFLLFGNENNFSNTVVAGVPPIPDYRKKLLNEFNIEISGGMGELKE
KIVRIGLLGVVDSRAVNKLLEATAKLLDKNYDYLPPRECKLPELLEKEVEWS

Sequences:

>Translated_372_residues
MLLIPGPVEVPRSVREASTLVVNHRSEKFREIVRKLESLMNKHFSASRTALLTGSGTLAVEAMVYSLIKPNEKVISFPYG
EFGNRLVDSLRRRGAQVKVYEKKIGEIFSIDEIKKALDENKDATAVALVHNETSSGMAFRNLEDVVSEVKRRGLKLLVDS
VSGFAAYKLLVNEWKIDAVATGSQKALASVPGMSFVALSDDGIEEIQGESLPSYLDISLHLKFQDKGETPFTPAVGVFNA
SLRAAELLEIEGIENRWKRHEACARFVREVLSSYGFLLFGNENNFSNTVVAGVPPIPDYRKKLLNEFNIEISGGMGELKE
KIVRIGLLGVVDSRAVNKLLEATAKLLDKNYDYLPPRECKLPELLEKEVEWS
>Mature_372_residues
MLLIPGPVEVPRSVREASTLVVNHRSEKFREIVRKLESLMNKHFSASRTALLTGSGTLAVEAMVYSLIKPNEKVISFPYG
EFGNRLVDSLRRRGAQVKVYEKKIGEIFSIDEIKKALDENKDATAVALVHNETSSGMAFRNLEDVVSEVKRRGLKLLVDS
VSGFAAYKLLVNEWKIDAVATGSQKALASVPGMSFVALSDDGIEEIQGESLPSYLDISLHLKFQDKGETPFTPAVGVFNA
SLRAAELLEIEGIENRWKRHEACARFVREVLSSYGFLLFGNENNFSNTVVAGVPPIPDYRKKLLNEFNIEISGGMGELKE
KIVRIGLLGVVDSRAVNKLLEATAKLLDKNYDYLPPRECKLPELLEKEVEWS

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=360, Percent_Identity=28.6111111111111, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=26.2247838616715, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321079, Length=377, Percent_Identity=28.9124668435013, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17530823, Length=343, Percent_Identity=25.3644314868805, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41371; Mature: 41371

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIPGPVEVPRSVREASTLVVNHRSEKFREIVRKLESLMNKHFSASRTALLTGSGTLAV
CEECCCCCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHH
EAMVYSLIKPNEKVISFPYGEFGNRLVDSLRRRGAQVKVYEKKIGEIFSIDEIKKALDEN
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCHHHHHHHHHCC
KDATAVALVHNETSSGMAFRNLEDVVSEVKRRGLKLLVDSVSGFAAYKLLVNEWKIDAVA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEE
TGSQKALASVPGMSFVALSDDGIEEIQGESLPSYLDISLHLKFQDKGETPFTPAVGVFNA
CCCHHHHHHCCCCEEEEECCCCHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHCC
SLRAAELLEIEGIENRWKRHEACARFVREVLSSYGFLLFGNENNFSNTVVAGVPPIPDYR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCCHHHH
KKLLNEFNIEISGGMGELKEKIVRIGLLGVVDSRAVNKLLEATAKLLDKNYDYLPPRECK
HHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LPELLEKEVEWS
CHHHHHHHCCCC
>Mature Secondary Structure
MLLIPGPVEVPRSVREASTLVVNHRSEKFREIVRKLESLMNKHFSASRTALLTGSGTLAV
CEECCCCCHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHH
EAMVYSLIKPNEKVISFPYGEFGNRLVDSLRRRGAQVKVYEKKIGEIFSIDEIKKALDEN
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCHHHHHHHHHCC
KDATAVALVHNETSSGMAFRNLEDVVSEVKRRGLKLLVDSVSGFAAYKLLVNEWKIDAVA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEE
TGSQKALASVPGMSFVALSDDGIEEIQGESLPSYLDISLHLKFQDKGETPFTPAVGVFNA
CCCHHHHHHCCCCEEEEECCCCHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHCC
SLRAAELLEIEGIENRWKRHEACARFVREVLSSYGFLLFGNENNFSNTVVAGVPPIPDYR
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCCHHHH
KKLLNEFNIEISGGMGELKEKIVRIGLLGVVDSRAVNKLLEATAKLLDKNYDYLPPRECK
HHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LPELLEKEVEWS
CHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]