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The map label for this gene is codA [H]

Identifier: 15921260

GI number: 15921260

Start: 998435

End: 999502

Strand: Direct

Name: codA [H]

Synonym: ST1014

Alternate gene names: 15921260

Gene position: 998435-999502 (Clockwise)

Preceding gene: 15921259

Following gene: 15921261

Centisome position: 37.05

GC content: 31.09

Gene sequence:

>1068_bases
GTGATATTGATAAAAATACCAGCCTTTTACGATATGCATTCACATCTAGAAAATGCCTTCATTGGTAATGAAGGTGCTAA
GAGTTTAGAAGAAGCTGTAGAAACATGGAGTAAAATAAGAGATAAGATGACACTTAATGAGATAAAGAAAAGAATTGAGA
AAGTGGCTTTGATAGAACTATTTTATGGTACAACTCACATAAGAGTCCATGCAGATACATGCTCTAAAAATAGTGTGAAA
GCGGCTATTTTAGCAAAAGATGAATTGAAAGAATATATTGATTTGCAAATTGTAGCATTTCCTGAGCAAGGCATATTTAA
GTGTTCAAAAGATGATTTTGTAAGATATTCCTCAATGGTTGATATAATTGGAGGAAAGCCTGAGGCTGACAACGACCCTT
ACCTTCATATGGATTTCATAGCCGAATTAGCATATAAACTTCAGAAGCCTATAGACGTTCATATTGACCAGCATGATGAG
AAAACCAAACATAGTGAGTATATGCTAGGAGTTATTAAAACTCATTTAGCCTTAAGTCATTTAACTGCTTTACATTTTTA
TTCTGAAAATTATGCTAAAAAGTTAATAAGAATGATTAAGGAAAAGAATGCAAGTGTAATTAGCTCACCATTAACAGCCT
TCTATCTTAATGGGGGTAATTCTTATCCGATGTTTAGAGGAGTCACAAGAGTAAAAGAGTTACTAAGAGAGAATATAAAT
GTTTGCTTAGGTCATGATGATACCCAAAACCCATTTTATCCAGCTGGTGTAGGTGATATGCTTCAAGTCTTATGGCTTCT
AATGAATATAGAAAAAACATTTGATATTTCATGGTTAGATTTAATAACTACTAATGCAGAAAAAGAATTTGGAAATAAAA
ACGAAGATTATATCTTAGTTGATTTGAAAGATGTTAAAGAACTTTTATTCACAATGATGCCAAGACACGTAGTTTTTAGA
AAAGGAAAAATTGTTGCTAAATCTACTGTAGAAGTGAAAGTATTAGATTTAAATCCATTTGATCTAATGAGAGAATTGTA
TAGAGATAACTTAAATAATTCATTATAA

Upstream 100 bases:

>100_bases
TTAGGGGTGTTGGAGAAAACAGCATTTCTGGTGCTTATGCATCTATTGCAAATGCAATTTCAGACTTTATCCCAGTCTAT
GAAATACCTATAAAGAGGGT

Downstream 100 bases:

>100_bases
TTGTAATTTAAATCTTGAGAGATACTGTATAATAAATTTAAATTTAATATCATTTTATCTAAATTTAAGCTTATATAGAC
TTACTCACATTCCCTATTAT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MILIKIPAFYDMHSHLENAFIGNEGAKSLEEAVETWSKIRDKMTLNEIKKRIEKVALIELFYGTTHIRVHADTCSKNSVK
AAILAKDELKEYIDLQIVAFPEQGIFKCSKDDFVRYSSMVDIIGGKPEADNDPYLHMDFIAELAYKLQKPIDVHIDQHDE
KTKHSEYMLGVIKTHLALSHLTALHFYSENYAKKLIRMIKEKNASVISSPLTAFYLNGGNSYPMFRGVTRVKELLRENIN
VCLGHDDTQNPFYPAGVGDMLQVLWLLMNIEKTFDISWLDLITTNAEKEFGNKNEDYILVDLKDVKELLFTMMPRHVVFR
KGKIVAKSTVEVKVLDLNPFDLMRELYRDNLNNSL

Sequences:

>Translated_355_residues
MILIKIPAFYDMHSHLENAFIGNEGAKSLEEAVETWSKIRDKMTLNEIKKRIEKVALIELFYGTTHIRVHADTCSKNSVK
AAILAKDELKEYIDLQIVAFPEQGIFKCSKDDFVRYSSMVDIIGGKPEADNDPYLHMDFIAELAYKLQKPIDVHIDQHDE
KTKHSEYMLGVIKTHLALSHLTALHFYSENYAKKLIRMIKEKNASVISSPLTAFYLNGGNSYPMFRGVTRVKELLRENIN
VCLGHDDTQNPFYPAGVGDMLQVLWLLMNIEKTFDISWLDLITTNAEKEFGNKNEDYILVDLKDVKELLFTMMPRHVVFR
KGKIVAKSTVEVKVLDLNPFDLMRELYRDNLNNSL
>Mature_355_residues
MILIKIPAFYDMHSHLENAFIGNEGAKSLEEAVETWSKIRDKMTLNEIKKRIEKVALIELFYGTTHIRVHADTCSKNSVK
AAILAKDELKEYIDLQIVAFPEQGIFKCSKDDFVRYSSMVDIIGGKPEADNDPYLHMDFIAELAYKLQKPIDVHIDQHDE
KTKHSEYMLGVIKTHLALSHLTALHFYSENYAKKLIRMIKEKNASVISSPLTAFYLNGGNSYPMFRGVTRVKELLRENIN
VCLGHDDTQNPFYPAGVGDMLQVLWLLMNIEKTFDISWLDLITTNAEKEFGNKNEDYILVDLKDVKELLFTMMPRHVVFR
KGKIVAKSTVEVKVLDLNPFDLMRELYRDNLNNSL

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=356, Percent_Identity=28.9325842696629, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786517, Length=364, Percent_Identity=23.3516483516484, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 40867; Mature: 40867

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIKIPAFYDMHSHLENAFIGNEGAKSLEEAVETWSKIRDKMTLNEIKKRIEKVALIEL
CEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYGTTHIRVHADTCSKNSVKAAILAKDELKEYIDLQIVAFPEQGIFKCSKDDFVRYSSMV
HCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHCEEEEEECCCCCEECCCHHHHHHHHHH
DIIGGKPEADNDPYLHMDFIAELAYKLQKPIDVHIDQHDEKTKHSEYMLGVIKTHLALSH
HHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LTALHFYSENYAKKLIRMIKEKNASVISSPLTAFYLNGGNSYPMFRGVTRVKELLRENIN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC
VCLGHDDTQNPFYPAGVGDMLQVLWLLMNIEKTFDISWLDLITTNAEKEFGNKNEDYILV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCCCEEEE
DLKDVKELLFTMMPRHVVFRKGKIVAKSTVEVKVLDLNPFDLMRELYRDNLNNSL
EHHHHHHHHHHHCCHHHHHCCCCEEEECEEEEEEEECCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MILIKIPAFYDMHSHLENAFIGNEGAKSLEEAVETWSKIRDKMTLNEIKKRIEKVALIEL
CEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYGTTHIRVHADTCSKNSVKAAILAKDELKEYIDLQIVAFPEQGIFKCSKDDFVRYSSMV
HCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHCEEEEEECCCCCEECCCHHHHHHHHHH
DIIGGKPEADNDPYLHMDFIAELAYKLQKPIDVHIDQHDEKTKHSEYMLGVIKTHLALSH
HHCCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LTALHFYSENYAKKLIRMIKEKNASVISSPLTAFYLNGGNSYPMFRGVTRVKELLRENIN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC
VCLGHDDTQNPFYPAGVGDMLQVLWLLMNIEKTFDISWLDLITTNAEKEFGNKNEDYILV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCCCEEEE
DLKDVKELLFTMMPRHVVFRKGKIVAKSTVEVKVLDLNPFDLMRELYRDNLNNSL
EHHHHHHHHHHHCCHHHHHCCCCEEEECEEEEEEEECCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]