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The map label for this gene is cutL [H]

Identifier: 15921259

GI number: 15921259

Start: 996525

End: 998438

Strand: Direct

Name: cutL [H]

Synonym: ST1013

Alternate gene names: 15921259

Gene position: 996525-998438 (Clockwise)

Preceding gene: 15921258

Following gene: 15921260

Centisome position: 36.98

GC content: 33.65

Gene sequence:

>1914_bases
ATGCTATATTATTATGTAGATGATATTAGGGGTAAATATAAAGTAGTAAGTTTTATAAGATCAAATAAACCTTATGCTAA
ATTTAGTATTAGGGGAAAGGTTTATACGTGGAAAGATATAGATTTCACTATTCCAAAAATCTTTGATAATGAGGGAAAGT
TAAAAGAGATAGAAATACCACTTTTAGCAAAAGATAGAGCATTATATACTGGTCAGCCGTTAGGAATGGTTATAGGAGAG
GATGAGTATGATGCCGAAGATAAGAAAGAGGAGGTTGAAGTAGAGTACGAAGATTTGAGTGGTCCGATCTATGAACCAGA
TAATGTAATACATTCTTTTTCTCAAGGAGAGTATGAATTTGGTGAAAATTCTTTCTCGTTAAAGCTCATATTTAATAGAC
AATCCCCAGCTCCTTTAGAAGGAAGAGGTGTAATTGTAACTCATGAGGATGGAAGATTAATAATACGAATTTCAACACAA
GCACCAACAGTAGCTAGGAAAATAGTCTCAAATATGCTAGATTTGAATGAGGAAAAAATTGAAATTAAAGTACCTAGAGT
AGGTGGAGGTTTTGGTGCCAAACAAGATATTATAATGGAAGAATTAGCCGTAATAGCTTTATCTTATGTAACTGGGGAAG
ACTTAAAGTGGATTGAAAGAAAGTCAGAACATATTATGACATCACAAGGCAGGGGTCAACAGCATGATGTGACTGTTTAT
TATAACAGTAATGGAAAAATAACGGGAATTATTGATAATATAACTTATGATATGGGTGCTTTTCCTTTACCATGGTCTGG
TATTTCACCCTTGTATGTCACACTTATGAACTTAAGGAATGTGTATGATATAAAAATAAAAACTAACGTAAAAGTAGTTG
CCTCTAACAATCCGCCACAAGGAGCTTTCAGAGGTTTTGGTAGGCCAGAAGCGTTCTTTGTTATAGAACGAATTATGGAT
GAAGTTAGTAGAAGATTAAAAATTGACCCTATCAATATTAGAGAAAAAAATTTAGGAAAAATCAATAATGATATAGGAGA
TGTAAAAAGGGTTTTAGAGAGATTAAGGGAGAGATATAATGAGTATAAAAAGAAATATAAGGTTGGTATAGGGGTTTCAC
TTTACGTTCATTATGCCTCACCTACATCTAAAGTTTTAATAGGTGAAGAAAAATCATTTATTGGTGGATATGAGTGCGTC
TCATTAAGGTTAACTAGCAATGGCATAGTTGAGGTTAAAACCACTACAGTTGACATGGGTCAAGGAATAAGTGATGTTTT
AAGAGAAATAGTGAAGAGGGAATTAGATTACGATAGAATTGTTGTTTATACTGGTTCACAAGATGTTAATGGGTTTGGTA
GTTGGGCTAGTAGGAGTGTAATTACTGCTGGGAACGCTACTCTTTTGGCTGCTAGGGAGTTAAAAGAGAAGATTGATAAA
CTTGGTGGGATAAAAAGAGTTTTAGAAAAATTAAATAATTCACCTTGGGAATTAGAAGAAAAAGAGTTGTACTCAATAAA
ATGTTATGAGCCGGAAGAATCAATTGGTGCAATAAGTGCTCAAATAAGTGTAGTTGAGTATGATGGTACAAATTTCCACT
TAAGAGAAAATTATATAATTATTGATATAGGAGTTCCTGCAGATGAGGACAAAGTAAAAGGACAAATAATTGGAGGAATA
ATACAAGCATTAGGTGGGGTTCTTTACGAGAATGTCAATGAACCTTATAATTATCTAATACCAACAGCCAAAGAGGTTCC
TAAAGTTGAAGTAGAATTACTTAATACACCTTCAAGTACTCCAGGTGGATTTAGGGGTGTTGGAGAAAACAGCATTTCTG
GTGCTTATGCATCTATTGCAAATGCAATTTCAGACTTTATCCCAGTCTATGAAATACCTATAAAGAGGGTGTGA

Upstream 100 bases:

>100_bases
GATTAACTTAATTAAGTAAATTCACTCTTTTTTCTTTTGTCAGAAATTATTTAGTTAAGATAAGAAAAAGATATAATAAT
AATACTCTTTATTTTATTTA

Downstream 100 bases:

>100_bases
TATTGATAAAAATACCAGCCTTTTACGATATGCATTCACATCTAGAAAATGCCTTCATTGGTAATGAAGGTGCTAAGAGT
TTAGAAGAAGCTGTAGAAAC

Product: quinoline 2-oxidoreductase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MLYYYVDDIRGKYKVVSFIRSNKPYAKFSIRGKVYTWKDIDFTIPKIFDNEGKLKEIEIPLLAKDRALYTGQPLGMVIGE
DEYDAEDKKEEVEVEYEDLSGPIYEPDNVIHSFSQGEYEFGENSFSLKLIFNRQSPAPLEGRGVIVTHEDGRLIIRISTQ
APTVARKIVSNMLDLNEEKIEIKVPRVGGGFGAKQDIIMEELAVIALSYVTGEDLKWIERKSEHIMTSQGRGQQHDVTVY
YNSNGKITGIIDNITYDMGAFPLPWSGISPLYVTLMNLRNVYDIKIKTNVKVVASNNPPQGAFRGFGRPEAFFVIERIMD
EVSRRLKIDPINIREKNLGKINNDIGDVKRVLERLRERYNEYKKKYKVGIGVSLYVHYASPTSKVLIGEEKSFIGGYECV
SLRLTSNGIVEVKTTTVDMGQGISDVLREIVKRELDYDRIVVYTGSQDVNGFGSWASRSVITAGNATLLAARELKEKIDK
LGGIKRVLEKLNNSPWELEEKELYSIKCYEPEESIGAISAQISVVEYDGTNFHLRENYIIIDIGVPADEDKVKGQIIGGI
IQALGGVLYENVNEPYNYLIPTAKEVPKVEVELLNTPSSTPGGFRGVGENSISGAYASIANAISDFIPVYEIPIKRV

Sequences:

>Translated_637_residues
MLYYYVDDIRGKYKVVSFIRSNKPYAKFSIRGKVYTWKDIDFTIPKIFDNEGKLKEIEIPLLAKDRALYTGQPLGMVIGE
DEYDAEDKKEEVEVEYEDLSGPIYEPDNVIHSFSQGEYEFGENSFSLKLIFNRQSPAPLEGRGVIVTHEDGRLIIRISTQ
APTVARKIVSNMLDLNEEKIEIKVPRVGGGFGAKQDIIMEELAVIALSYVTGEDLKWIERKSEHIMTSQGRGQQHDVTVY
YNSNGKITGIIDNITYDMGAFPLPWSGISPLYVTLMNLRNVYDIKIKTNVKVVASNNPPQGAFRGFGRPEAFFVIERIMD
EVSRRLKIDPINIREKNLGKINNDIGDVKRVLERLRERYNEYKKKYKVGIGVSLYVHYASPTSKVLIGEEKSFIGGYECV
SLRLTSNGIVEVKTTTVDMGQGISDVLREIVKRELDYDRIVVYTGSQDVNGFGSWASRSVITAGNATLLAARELKEKIDK
LGGIKRVLEKLNNSPWELEEKELYSIKCYEPEESIGAISAQISVVEYDGTNFHLRENYIIIDIGVPADEDKVKGQIIGGI
IQALGGVLYENVNEPYNYLIPTAKEVPKVEVELLNTPSSTPGGFRGVGENSISGAYASIANAISDFIPVYEIPIKRV
>Mature_637_residues
MLYYYVDDIRGKYKVVSFIRSNKPYAKFSIRGKVYTWKDIDFTIPKIFDNEGKLKEIEIPLLAKDRALYTGQPLGMVIGE
DEYDAEDKKEEVEVEYEDLSGPIYEPDNVIHSFSQGEYEFGENSFSLKLIFNRQSPAPLEGRGVIVTHEDGRLIIRISTQ
APTVARKIVSNMLDLNEEKIEIKVPRVGGGFGAKQDIIMEELAVIALSYVTGEDLKWIERKSEHIMTSQGRGQQHDVTVY
YNSNGKITGIIDNITYDMGAFPLPWSGISPLYVTLMNLRNVYDIKIKTNVKVVASNNPPQGAFRGFGRPEAFFVIERIMD
EVSRRLKIDPINIREKNLGKINNDIGDVKRVLERLRERYNEYKKKYKVGIGVSLYVHYASPTSKVLIGEEKSFIGGYECV
SLRLTSNGIVEVKTTTVDMGQGISDVLREIVKRELDYDRIVVYTGSQDVNGFGSWASRSVITAGNATLLAARELKEKIDK
LGGIKRVLEKLNNSPWELEEKELYSIKCYEPEESIGAISAQISVVEYDGTNFHLRENYIIIDIGVPADEDKVKGQIIGGI
IQALGGVLYENVNEPYNYLIPTAKEVPKVEVELLNTPSSTPGGFRGVGENSISGAYASIANAISDFIPVYEIPIKRV

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=655, Percent_Identity=22.1374045801527, Blast_Score=85, Evalue=3e-16,
Organism=Escherichia coli, GI1789230, Length=693, Percent_Identity=25.5411255411255, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789246, Length=563, Percent_Identity=25.044404973357, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=550, Percent_Identity=24, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24647193, Length=646, Percent_Identity=23.374613003096, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737937, Length=721, Percent_Identity=22.746185852982, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647199, Length=512, Percent_Identity=21.6796875, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647201, Length=503, Percent_Identity=21.8687872763419, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 71574; Mature: 71574

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYYVDDIRGKYKVVSFIRSNKPYAKFSIRGKVYTWKDIDFTIPKIFDNEGKLKEIEIP
CEEEEEECCCCCCEEEHHHHCCCCEEEEEEEEEEEEEECCCEECCCEECCCCCEEEEECC
LLAKDRALYTGQPLGMVIGEDEYDAEDKKEEVEVEYEDLSGPIYEPDNVIHSFSQGEYEF
EEECCCEEECCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEC
GENSFSLKLIFNRQSPAPLEGRGVIVTHEDGRLIIRISTQAPTVARKIVSNMLDLNEEKI
CCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
EIKVPRVGGGFGAKQDIIMEELAVIALSYVTGEDLKWIERKSEHIMTSQGRGQQHDVTVY
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCEEEE
YNSNGKITGIIDNITYDMGAFPLPWSGISPLYVTLMNLRNVYDIKIKTNVKVVASNNPPQ
ECCCCEEEEEEECCEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEEEEEEECCCCCC
GAFRGFGRPEAFFVIERIMDEVSRRLKIDPINIREKNLGKINNDIGDVKRVLERLRERYN
HHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EYKKKYKVGIGVSLYVHYASPTSKVLIGEEKSFIGGYECVSLRLTSNGIVEVKTTTVDMG
HHHHHEEEECEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEECCCEEEEEEEEEECC
QGISDVLREIVKRELDYDRIVVYTGSQDVNGFGSWASRSVITAGNATLLAARELKEKIDK
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHH
LGGIKRVLEKLNNSPWELEEKELYSIKCYEPEESIGAISAQISVVEYDGTNFHLRENYII
HCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHCEEEEEEEEEEECCCEEEEECCEEE
IDIGVPADEDKVKGQIIGGIIQALGGVLYENVNEPYNYLIPTAKEVPKVEVELLNTPSST
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEECCCCC
PGGFRGVGENSISGAYASIANAISDFIPVYEIPIKRV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
MLYYYVDDIRGKYKVVSFIRSNKPYAKFSIRGKVYTWKDIDFTIPKIFDNEGKLKEIEIP
CEEEEEECCCCCCEEEHHHHCCCCEEEEEEEEEEEEEECCCEECCCEECCCCCEEEEECC
LLAKDRALYTGQPLGMVIGEDEYDAEDKKEEVEVEYEDLSGPIYEPDNVIHSFSQGEYEF
EEECCCEEECCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEC
GENSFSLKLIFNRQSPAPLEGRGVIVTHEDGRLIIRISTQAPTVARKIVSNMLDLNEEKI
CCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
EIKVPRVGGGFGAKQDIIMEELAVIALSYVTGEDLKWIERKSEHIMTSQGRGQQHDVTVY
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCEEEE
YNSNGKITGIIDNITYDMGAFPLPWSGISPLYVTLMNLRNVYDIKIKTNVKVVASNNPPQ
ECCCCEEEEEEECCEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEEEEEEECCCCCC
GAFRGFGRPEAFFVIERIMDEVSRRLKIDPINIREKNLGKINNDIGDVKRVLERLRERYN
HHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EYKKKYKVGIGVSLYVHYASPTSKVLIGEEKSFIGGYECVSLRLTSNGIVEVKTTTVDMG
HHHHHEEEECEEEEEEEECCCCCEEEEECCCCCCCCEEEEEEEEECCCEEEEEEEEEECC
QGISDVLREIVKRELDYDRIVVYTGSQDVNGFGSWASRSVITAGNATLLAARELKEKIDK
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCCEEEEHHHHHHHHHHH
LGGIKRVLEKLNNSPWELEEKELYSIKCYEPEESIGAISAQISVVEYDGTNFHLRENYII
HCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHCEEEEEEEEEEECCCEEEEECCEEE
IDIGVPADEDKVKGQIIGGIIQALGGVLYENVNEPYNYLIPTAKEVPKVEVELLNTPSST
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEEEECCCCC
PGGFRGVGENSISGAYASIANAISDFIPVYEIPIKRV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]