Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 15920932

GI number: 15920932

Start: 686115

End: 687563

Strand: Reverse

Name: appC [H]

Synonym: ST0702

Alternate gene names: 15920932

Gene position: 687563-686115 (Counterclockwise)

Preceding gene: 15920933

Following gene: 15920931

Centisome position: 25.51

GC content: 33.61

Gene sequence:

>1449_bases
ATGAATAAATTTGTAAAAGATCTTTTACATAGAAAATCCTTTATAATCTCAGTAATCATTATAGCAATATTCGTTTTTAT
AGCTGCAGCAGCACCTATTCTTACCCCTTATTCAAACCCATATTCTACAACAGAATATTTTGTTGCTGGTCCTTATGCGG
TTCCTTCTTGGGCCACTATATTTCCACAATACAAACTTTATCCCCCTAACATGCAGTTCGCTTTGATCAATCCAAAAATT
TTTGGTAACGTTTCTTACTCTTTTAATAATGATAGGTATGTTATAACTATCCCACCAGGTAAATATTTTAATTTGACTTA
CACATTCTATTGGAAGTATATTGCTCCTTATTCCTTTTCGATATCTTTTAACGTAACGCCAATAACAACTCAAGGAGTTC
AAGTAAATATATATTTCATAAATTCAACCAACTTTAAATATTTCTTAGAAAGCTTCGCACCAGAATCTTATGCATCTGCA
TTTACATATCCGATTGAGACTTTATATTTAAATAAGGTTAACACAATAACCGTGAACTCTTTATATTTAAATCCTGATAA
TAGTCCATTCTTTGCTTCGTTAAGTGCTTATGAGCAGACCATATACAGCTTAACCTTTGAAGACTATACTTTAGGCAAAC
CTGGTGAAGCTACTATTATGATCTCAATAGTTAATCTTGGAAATACTCCAGCTAAGATAATATTAACTAATCCAATTTTT
AGTGACAAAGGAAAAGCTTTTGGTATTTTAGGTACTGATGATAACGGAGCTAGTGTATTTGCTGAATTTGTGTATGGAAC
TAGATTTGATTTGATACTTAGTTTATTAGCCTCCATATTAATTGTGGGAATAGGTTTAGTAGCAGGACTTGTAGCAGGAT
ATGTAGGTGGTAAAGCTGATCTAATACTTAATTCTATCACGGACTTCTTCCTTACTATACCTGGACTGCCATTCATAATT
GTGCTGGAAACTGTTCTTTTAGTTTCTGGTGTATTAGCTCACATAAGTGAGGCTGATCTAATATTGCTAATAATTGCTGG
TTTATCATGGATGGGTACCATGAAAATAATTAGATCTGTAACCTTATCTATAAAGAGTAGAACATTTATAGAGGCTACTA
AGGCCTTAGGTGGTAACTCGTTCTACATTATTAGAAGGCATGTTTTACCTAATATTTTAGGAGTAGTATTTGCACAAATA
GCATATGATGTCCCTACTGTTATATTAATTGAATCGGGACTTGATTTCTTAGGCCTAGGAATTACCAGTTTTCCTACATG
GGGTAATATGTTAGGATTTGCTACTGATGCTGCTTCTTCAGCTACTAGTTTTGCTTGGTGGTGGGTTCTTCCACCAGGAC
TGGGTATAGTTCTTCTCTCGATAGGTTTCTATTATTTGGGAACTGCATTACAAGATGTATTAAGCCCATATAGAATAAGA
GGAGAATAA

Upstream 100 bases:

>100_bases
TACTTGAAGCCGTATTCTATATAATTAATCTATATGCAATAATCGTACTTTTGGTTTTAGATTTAGTTTATCCGTTCATA
GACCCTAGGGTGAAGTATGA

Downstream 100 bases:

>100_bases
AGATGATTGATAGTGCTATTCTTTCAATAAAAGGATTAAAAACATATTATAAAACTAGAGATGGTTATGTCAAAGCTGTT
GATGATGTAAGTTTTGACGT

Product: oligopeptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNKFVKDLLHRKSFIISVIIIAIFVFIAAAAPILTPYSNPYSTTEYFVAGPYAVPSWATIFPQYKLYPPNMQFALINPKI
FGNVSYSFNNDRYVITIPPGKYFNLTYTFYWKYIAPYSFSISFNVTPITTQGVQVNIYFINSTNFKYFLESFAPESYASA
FTYPIETLYLNKVNTITVNSLYLNPDNSPFFASLSAYEQTIYSLTFEDYTLGKPGEATIMISIVNLGNTPAKIILTNPIF
SDKGKAFGILGTDDNGASVFAEFVYGTRFDLILSLLASILIVGIGLVAGLVAGYVGGKADLILNSITDFFLTIPGLPFII
VLETVLLVSGVLAHISEADLILLIIAGLSWMGTMKIIRSVTLSIKSRTFIEATKALGGNSFYIIRRHVLPNILGVVFAQI
AYDVPTVILIESGLDFLGLGITSFPTWGNMLGFATDAASSATSFAWWWVLPPGLGIVLLSIGFYYLGTALQDVLSPYRIR
GE

Sequences:

>Translated_482_residues
MNKFVKDLLHRKSFIISVIIIAIFVFIAAAAPILTPYSNPYSTTEYFVAGPYAVPSWATIFPQYKLYPPNMQFALINPKI
FGNVSYSFNNDRYVITIPPGKYFNLTYTFYWKYIAPYSFSISFNVTPITTQGVQVNIYFINSTNFKYFLESFAPESYASA
FTYPIETLYLNKVNTITVNSLYLNPDNSPFFASLSAYEQTIYSLTFEDYTLGKPGEATIMISIVNLGNTPAKIILTNPIF
SDKGKAFGILGTDDNGASVFAEFVYGTRFDLILSLLASILIVGIGLVAGLVAGYVGGKADLILNSITDFFLTIPGLPFII
VLETVLLVSGVLAHISEADLILLIIAGLSWMGTMKIIRSVTLSIKSRTFIEATKALGGNSFYIIRRHVLPNILGVVFAQI
AYDVPTVILIESGLDFLGLGITSFPTWGNMLGFATDAASSATSFAWWWVLPPGLGIVLLSIGFYYLGTALQDVLSPYRIR
GE
>Mature_482_residues
MNKFVKDLLHRKSFIISVIIIAIFVFIAAAAPILTPYSNPYSTTEYFVAGPYAVPSWATIFPQYKLYPPNMQFALINPKI
FGNVSYSFNNDRYVITIPPGKYFNLTYTFYWKYIAPYSFSISFNVTPITTQGVQVNIYFINSTNFKYFLESFAPESYASA
FTYPIETLYLNKVNTITVNSLYLNPDNSPFFASLSAYEQTIYSLTFEDYTLGKPGEATIMISIVNLGNTPAKIILTNPIF
SDKGKAFGILGTDDNGASVFAEFVYGTRFDLILSLLASILIVGIGLVAGLVAGYVGGKADLILNSITDFFLTIPGLPFII
VLETVLLVSGVLAHISEADLILLIIAGLSWMGTMKIIRSVTLSIKSRTFIEATKALGGNSFYIIRRHVLPNILGVVFAQI
AYDVPTVILIESGLDFLGLGITSFPTWGNMLGFATDAASSATSFAWWWVLPPGLGIVLLSIGFYYLGTALQDVLSPYRIR
GE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=227, Percent_Identity=28.1938325991189, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787498, Length=227, Percent_Identity=33.920704845815, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789964, Length=244, Percent_Identity=31.5573770491803, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787054, Length=232, Percent_Identity=29.7413793103448, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788505, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789889, Length=252, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 53099; Mature: 53099

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFVKDLLHRKSFIISVIIIAIFVFIAAAAPILTPYSNPYSTTEYFVAGPYAVPSWATI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCEEEEECCCCCCCHHHH
FPQYKLYPPNMQFALINPKIFGNVSYSFNNDRYVITIPPGKYFNLTYTFYWKYIAPYSFS
CCCEEECCCCCEEEEECCEEEEEEEEEECCCEEEEEECCCCEEEEEEEEEEEEECCEEEE
ISFNVTPITTQGVQVNIYFINSTNFKYFLESFAPESYASAFTYPIETLYLNKVNTITVNS
EEEEEEEEEECCEEEEEEEEECCCHHHHHHHHCCHHHHHHEECEEEEEEECCCEEEEEEE
LYLNPDNSPFFASLSAYEQTIYSLTFEDYTLGKPGEATIMISIVNLGNTPAKIILTNPIF
EEECCCCCCEEEEHHHHHHHHEEEEECCEECCCCCCCEEEEEEEECCCCCEEEEEECCCC
SDKGKAFGILGTDDNGASVFAEFVYGTRFDLILSLLASILIVGIGLVAGLVAGYVGGKAD
CCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LILNSITDFFLTIPGLPFIIVLETVLLVSGVLAHISEADLILLIIAGLSWMGTMKIIRSV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
TLSIKSRTFIEATKALGGNSFYIIRRHVLPNILGVVFAQIAYDVPTVILIESGLDFLGLG
HHHHCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECC
ITSFPTWGNMLGFATDAASSATSFAWWWVLPPGLGIVLLSIGFYYLGTALQDVLSPYRIR
CCCCCCCCCHHEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEC
GE
CC
>Mature Secondary Structure
MNKFVKDLLHRKSFIISVIIIAIFVFIAAAAPILTPYSNPYSTTEYFVAGPYAVPSWATI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCEEEEECCCCCCCHHHH
FPQYKLYPPNMQFALINPKIFGNVSYSFNNDRYVITIPPGKYFNLTYTFYWKYIAPYSFS
CCCEEECCCCCEEEEECCEEEEEEEEEECCCEEEEEECCCCEEEEEEEEEEEEECCEEEE
ISFNVTPITTQGVQVNIYFINSTNFKYFLESFAPESYASAFTYPIETLYLNKVNTITVNS
EEEEEEEEEECCEEEEEEEEECCCHHHHHHHHCCHHHHHHEECEEEEEEECCCEEEEEEE
LYLNPDNSPFFASLSAYEQTIYSLTFEDYTLGKPGEATIMISIVNLGNTPAKIILTNPIF
EEECCCCCCEEEEHHHHHHHHEEEEECCEECCCCCCCEEEEEEEECCCCCEEEEEECCCC
SDKGKAFGILGTDDNGASVFAEFVYGTRFDLILSLLASILIVGIGLVAGLVAGYVGGKAD
CCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LILNSITDFFLTIPGLPFIIVLETVLLVSGVLAHISEADLILLIIAGLSWMGTMKIIRSV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
TLSIKSRTFIEATKALGGNSFYIIRRHVLPNILGVVFAQIAYDVPTVILIESGLDFLGLG
HHHHCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECC
ITSFPTWGNMLGFATDAASSATSFAWWWVLPPGLGIVLLSIGFYYLGTALQDVLSPYRIR
CCCCCCCCCHHEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]