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The map label for this gene is napA [H]

Identifier: 15920858

GI number: 15920858

Start: 622168

End: 623367

Strand: Direct

Name: napA [H]

Synonym: ST0638

Alternate gene names: 15920858

Gene position: 622168-623367 (Clockwise)

Preceding gene: 15920855

Following gene: 15920859

Centisome position: 23.09

GC content: 31.58

Gene sequence:

>1200_bases
GTGAATACAAATGATATAGTAATTTTGACACTCCTTGAGCTTTCTATTTTACTTACAGCCTCTCAAACAGTTAGACTACT
AACCCAAAAATATTATTTACCATCGATATTCGCAGAGTTACTAGTTGGTATAATTCTTAGTCCTTATGCTGTAGGCGGAA
TTATAAATGAGGTATTTAATGTGCACTTATTTGATATAAACTCGTATCTGACATTATTTGCGAACTTCTCGGTAATTTTA
CTGATTTTTGCTGCTGGTTTGTCACATGGCTATAAAAATTTGAAATCTTCTGGGCTTCTAGGTTTTCTAGCAGCAACATT
CGGAGCCGTTATACCAACTATTTTAGTTTACTTTACCTTTGGTATAATTTATCCTTCTCAAGTTTCCGCATTAATGGGTG
CTGCTAGTGCTGCTACAAGTTTAGCTGCTACTTCGTCAATAATAGAAGATTTCAAATTATATAGAAGAAATTTCGCTAGA
ATAGTTATATCAGCAGCAGCAATAGATGATGTAGTTTCCTTAATAATTCTTTCTGTTGTACTAGAAATATTAAGTATAAA
GATTCTGTCATTTATAACAATTTTCTATAATATTTCATTAACTATAATTTCCTGGGTCATAGTTCTATTTCTTTCAATAA
TTATAATTCCACGAATTTTGAAATACATAAGAGATGATTTAGTTAACGATGTATCTTTAGTTATTCTCTTTTTAGTTGTT
TTTCTAATGATTTTGTTAGGATTTGAACCAATTATAGCTGCTTTTATAGTTGGTATAGCTGTAGCAGAAAGTGTCAAATC
ATCGAGAATAACATCCTTCACTTCTTCCCTATTAGCAATTTTCGGTCCGGTATTCTTTATTTATGTTGGAATGGAAACAC
CAATATCCATATTTATAAACGTTGACGATGTATTATTAGGTCTTCTTATGACGTTTCTAGCAATAATAGGTAAAATTGCC
GGTATATTTCCTTTTGCTTTTCTTTATACTAAAGACCTTAAGGAGTCTTTTTTAGCATCTGTAGGTATGTTACCAAGAGG
AGAAGTGGGATTAATTATTGCGACATTAGGTTTATCTTCTGCAATACTTGACGTTAATCAATTCTCTCAAGTTGTAATTA
TGGCTTTGCTTACTACGTTAATAGGTGGTTCGCTTTTCTCATATCTTGTGAGAAAATGGATTTTAGAGCATTCAGCTTAA

Upstream 100 bases:

>100_bases
TAAATGATCTATGTGATATATCTTCTCTTTTCCTCTTCTTAAAATTGGCATTAGGTATATGTAACAAATTATAAAAATAA
AATTACGCTATTTGAATCAT

Downstream 100 bases:

>100_bases
AGGAATTTCTTCACCATTCAGTTACGGTCGCACACATCACTAAGTTTTAATATATACTAGACTATAAAAGAATAATGATT
GCATGTACAAGGGACTGTTA

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNTNDIVILTLLELSILLTASQTVRLLTQKYYLPSIFAELLVGIILSPYAVGGIINEVFNVHLFDINSYLTLFANFSVIL
LIFAAGLSHGYKNLKSSGLLGFLAATFGAVIPTILVYFTFGIIYPSQVSALMGAASAATSLAATSSIIEDFKLYRRNFAR
IVISAAAIDDVVSLIILSVVLEILSIKILSFITIFYNISLTIISWVIVLFLSIIIIPRILKYIRDDLVNDVSLVILFLVV
FLMILLGFEPIIAAFIVGIAVAESVKSSRITSFTSSLLAIFGPVFFIYVGMETPISIFINVDDVLLGLLMTFLAIIGKIA
GIFPFAFLYTKDLKESFLASVGMLPRGEVGLIIATLGLSSAILDVNQFSQVVIMALLTTLIGGSLFSYLVRKWILEHSA

Sequences:

>Translated_399_residues
MNTNDIVILTLLELSILLTASQTVRLLTQKYYLPSIFAELLVGIILSPYAVGGIINEVFNVHLFDINSYLTLFANFSVIL
LIFAAGLSHGYKNLKSSGLLGFLAATFGAVIPTILVYFTFGIIYPSQVSALMGAASAATSLAATSSIIEDFKLYRRNFAR
IVISAAAIDDVVSLIILSVVLEILSIKILSFITIFYNISLTIISWVIVLFLSIIIIPRILKYIRDDLVNDVSLVILFLVV
FLMILLGFEPIIAAFIVGIAVAESVKSSRITSFTSSLLAIFGPVFFIYVGMETPISIFINVDDVLLGLLMTFLAIIGKIA
GIFPFAFLYTKDLKESFLASVGMLPRGEVGLIIATLGLSSAILDVNQFSQVVIMALLTTLIGGSLFSYLVRKWILEHSA
>Mature_399_residues
MNTNDIVILTLLELSILLTASQTVRLLTQKYYLPSIFAELLVGIILSPYAVGGIINEVFNVHLFDINSYLTLFANFSVIL
LIFAAGLSHGYKNLKSSGLLGFLAATFGAVIPTILVYFTFGIIYPSQVSALMGAASAATSLAATSSIIEDFKLYRRNFAR
IVISAAAIDDVVSLIILSVVLEILSIKILSFITIFYNISLTIISWVIVLFLSIIIIPRILKYIRDDLVNDVSLVILFLVV
FLMILLGFEPIIAAFIVGIAVAESVKSSRITSFTSSLLAIFGPVFFIYVGMETPISIFINVDDVLLGLLMTFLAIIGKIA
GIFPFAFLYTKDLKESFLASVGMLPRGEVGLIIATLGLSSAILDVNQFSQVVIMALLTTLIGGSLFSYLVRKWILEHSA

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 43455; Mature: 43455

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNDIVILTLLELSILLTASQTVRLLTQKYYLPSIFAELLVGIILSPYAVGGIINEVFN
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHLFDINSYLTLFANFSVILLIFAAGLSHGYKNLKSSGLLGFLAATFGAVIPTILVYFTF
HHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GIIYPSQVSALMGAASAATSLAATSSIIEDFKLYRRNFARIVISAAAIDDVVSLIILSVV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEILSIKILSFITIFYNISLTIISWVIVLFLSIIIIPRILKYIRDDLVNDVSLVILFLVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLMILLGFEPIIAAFIVGIAVAESVKSSRITSFTSSLLAIFGPVFFIYVGMETPISIFIN
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
VDDVLLGLLMTFLAIIGKIAGIFPFAFLYTKDLKESFLASVGMLPRGEVGLIIATLGLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AILDVNQFSQVVIMALLTTLIGGSLFSYLVRKWILEHSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTNDIVILTLLELSILLTASQTVRLLTQKYYLPSIFAELLVGIILSPYAVGGIINEVFN
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHLFDINSYLTLFANFSVILLIFAAGLSHGYKNLKSSGLLGFLAATFGAVIPTILVYFTF
HHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GIIYPSQVSALMGAASAATSLAATSSIIEDFKLYRRNFARIVISAAAIDDVVSLIILSVV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEILSIKILSFITIFYNISLTIISWVIVLFLSIIIIPRILKYIRDDLVNDVSLVILFLVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLMILLGFEPIIAAFIVGIAVAESVKSSRITSFTSSLLAIFGPVFFIYVGMETPISIFIN
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
VDDVLLGLLMTFLAIIGKIAGIFPFAFLYTKDLKESFLASVGMLPRGEVGLIIATLGLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AILDVNQFSQVVIMALLTTLIGGSLFSYLVRKWILEHSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]