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The map label for this gene is nagD [H]

Identifier: 15920712

GI number: 15920712

Start: 494599

End: 495393

Strand: Direct

Name: nagD [H]

Synonym: ST0496

Alternate gene names: 15920712

Gene position: 494599-495393 (Clockwise)

Preceding gene: 15920711

Following gene: 15920713

Centisome position: 18.35

GC content: 30.31

Gene sequence:

>795_bases
ATGTTATTGGATGATTATGAACTTATAATAAGTGATGTAGATGGAGTCTTGGTCAGAGAAGGAGAACCTATATGGAGTAA
TATTGTAGCAATCAAGAAAATTATAGAAAGAGGTAAAAAAGTATTATTAATTACTAATAATTCTGGTTTTAGTAGGGTAA
TTTTATCTAGACAATTAAATTATTTAGGAGTAAAGATAGAGCCTAAAGACATTATAACTAGTGGAACTGCAGCAGCAATT
TATCTTAAGGAAAGGACTAATGTGAAAACTGTTTTTGTTGTGGGTGAAGAAGGACTAATCGAGGAATTAAAAAATTTTAA
TTTTAGAATAATTAGCTCAAATGAAGTAGAAGAGGAAATACCAGACGCAGTAGTTTTAGGTCTAGACAGATTAAGTACAT
ACGAAAAATTATCTACAGCAATGAGGTGTATTTACAAAGGTTCTAAGTTTATAGTTACAAATATGGATAGGCTTTGGCCT
TCTAAGGATGGTTTAAAATTAGGAGCCGGTGCATTAGCGTCTGCTATAATTTATGCACTTCAGCGAGAGCCTGACTTTAT
AGCCGGTAAACCAAATACTTGGATTATAGAAATAGCATTGAAATTATCTGGCATAAATAATTTGAATAAAGCTGTTATAA
TTGGTGATCAATTAGAGACTGATATAAAAATGGGTATTAATGCTGGTATAGATACAATTTTGGTTTTAACTGGTATATCT
TCGATAAAAGATATTGAGAGAACAAATATTAAACCTAAGTTTGTAGTAAACTCTCTAAATGAAATTGTGAAATAA

Upstream 100 bases:

>100_bases
GAGAGTATACTTTATTATCCTTTTGGATATTTTGTGTTTGCCGAGGACGAAAATAAGCTAATAGAAAAAATAAAGATAAA
AATGAACGAGTTGAAGTCCA

Downstream 100 bases:

>100_bases
AGGTTTTTTAGTCAAAATACACATTTACTCATGTGGAGAAAGTTTCATACGATGTTGTAATCGTAGGAGCTGGGTTAGCT
GGATTAATGGCAGCACACGA

Product: hypothetical protein

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLLDDYELIISDVDGVLVREGEPIWSNIVAIKKIIERGKKVLLITNNSGFSRVILSRQLNYLGVKIEPKDIITSGTAAAI
YLKERTNVKTVFVVGEEGLIEELKNFNFRIISSNEVEEEIPDAVVLGLDRLSTYEKLSTAMRCIYKGSKFIVTNMDRLWP
SKDGLKLGAGALASAIIYALQREPDFIAGKPNTWIIEIALKLSGINNLNKAVIIGDQLETDIKMGINAGIDTILVLTGIS
SIKDIERTNIKPKFVVNSLNEIVK

Sequences:

>Translated_264_residues
MLLDDYELIISDVDGVLVREGEPIWSNIVAIKKIIERGKKVLLITNNSGFSRVILSRQLNYLGVKIEPKDIITSGTAAAI
YLKERTNVKTVFVVGEEGLIEELKNFNFRIISSNEVEEEIPDAVVLGLDRLSTYEKLSTAMRCIYKGSKFIVTNMDRLWP
SKDGLKLGAGALASAIIYALQREPDFIAGKPNTWIIEIALKLSGINNLNKAVIIGDQLETDIKMGINAGIDTILVLTGIS
SIKDIERTNIKPKFVVNSLNEIVK
>Mature_264_residues
MLLDDYELIISDVDGVLVREGEPIWSNIVAIKKIIERGKKVLLITNNSGFSRVILSRQLNYLGVKIEPKDIITSGTAAAI
YLKERTNVKTVFVVGEEGLIEELKNFNFRIISSNEVEEEIPDAVVLGLDRLSTYEKLSTAMRCIYKGSKFIVTNMDRLWP
SKDGLKLGAGALASAIIYALQREPDFIAGKPNTWIIEIALKLSGINNLNKAVIIGDQLETDIKMGINAGIDTILVLTGIS
SIKDIERTNIKPKFVVNSLNEIVK

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI108796653, Length=295, Percent_Identity=29.4915254237288, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI10092677, Length=273, Percent_Identity=27.1062271062271, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI14149777, Length=258, Percent_Identity=29.8449612403101, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786890, Length=254, Percent_Identity=33.4645669291339, Blast_Score=128, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17562458, Length=293, Percent_Identity=26.962457337884, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560956, Length=293, Percent_Identity=26.962457337884, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17558880, Length=293, Percent_Identity=26.962457337884, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193210059, Length=274, Percent_Identity=26.6423357664234, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71984613, Length=277, Percent_Identity=25.2707581227437, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562356, Length=209, Percent_Identity=31.1004784688995, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319965, Length=245, Percent_Identity=26.1224489795918, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24666141, Length=270, Percent_Identity=31.4814814814815, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24656326, Length=260, Percent_Identity=27.6923076923077, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24656330, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22026920, Length=258, Percent_Identity=29.8449612403101, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19920940, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666137, Length=297, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859765, Length=282, Percent_Identity=22.6950354609929, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221329670, Length=285, Percent_Identity=23.1578947368421, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 29233; Mature: 29233

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDDYELIISDVDGVLVREGEPIWSNIVAIKKIIERGKKVLLITNNSGFSRVILSRQLN
CCCCCHHHHEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCHH
YLGVKIEPKDIITSGTAAAIYLKERTNVKTVFVVGEEGLIEELKNFNFRIISSNEVEEEI
EEEEEECHHHHCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHCCCEEEEECCCHHHHC
PDAVVLGLDRLSTYEKLSTAMRCIYKGSKFIVTNMDRLWPSKDGLKLGAGALASAIIYAL
CHHEEECHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCEECHHHHHHHHHHHH
QREPDFIAGKPNTWIIEIALKLSGINNLNKAVIIGDQLETDIKMGINAGIDTILVLTGIS
HCCCCEECCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHEECCCH
SIKDIERTNIKPKFVVNSLNEIVK
HHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLLDDYELIISDVDGVLVREGEPIWSNIVAIKKIIERGKKVLLITNNSGFSRVILSRQLN
CCCCCHHHHEECCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCHH
YLGVKIEPKDIITSGTAAAIYLKERTNVKTVFVVGEEGLIEELKNFNFRIISSNEVEEEI
EEEEEECHHHHCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHCCCEEEEECCCHHHHC
PDAVVLGLDRLSTYEKLSTAMRCIYKGSKFIVTNMDRLWPSKDGLKLGAGALASAIIYAL
CHHEEECHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCEECHHHHHHHHHHHH
QREPDFIAGKPNTWIIEIALKLSGINNLNKAVIIGDQLETDIKMGINAGIDTILVLTGIS
HCCCCEECCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHEECCCH
SIKDIERTNIKPKFVVNSLNEIVK
HHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA