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The map label for this gene is 15920656

Identifier: 15920656

GI number: 15920656

Start: 450804

End: 451547

Strand: Reverse

Name: 15920656

Synonym: ST0444

Alternate gene names: NA

Gene position: 451547-450804 (Counterclockwise)

Preceding gene: 15920657

Following gene: 15920655

Centisome position: 16.76

GC content: 33.47

Gene sequence:

>744_bases
ATGTCTAATAGTAAGATATATTTTGAAGATAGAAGCATAGTCACCCCAGGAGATTTAATTGCCGAAGGAGACTTTCAAAT
ACCATGGTCACCATATTATTATAAGATAGGAAATAAATATTATTCGTCCATAACAGGTTTAATAGAAGTCAAGGAAAATT
TATTTGAGATAGTTCCATTAGAAGGACATAGATATATCCCGAAAGTTGGTGATACAGTTATTGGATTAATAGAAGATGTT
GAAATTTATGGATGGGTTCTGGATATAAAATCACCTTATTCTGCATACTTACCAGCTTCTTCATTCTTAGGTAGGCCAGT
TAGCCCAGGAGAGGACTTGCGTAGATACCTTAATTTGGGAGATTACGTAATTGCTAAAATAGAAACCTATGATAGAACGA
TAAATCCTATTTTATCTATAAAAGGGAAAGGTTTAGGAAGAGTATCTAGCGGAATAGTAATTGATATACCTCCAGTAAAA
GTCCCGAGAGTAATCGGGAAAAACAGAAGCATGCTTGACACATTAACTAGCGAAACAGGCTGTGAAATTCTTGTTGCTCA
AAATGGAAGAATACTAGCTAATTGTGCTACTAAGATGATTGAAGAAGCTTTAGTTGAAGCTATTCAGATTATAGAAAAAG
AATCTCATATAAAAGGACTAACGGAAAAAATAAGAAAGTTTTTGAGAGAAAAATTAGGTGAGACAAAAAATGATTCAGCT
ACAAAAACCGAGGCTAATACTTGA

Upstream 100 bases:

>100_bases
GAAATCCCAGCAGGAATGCAACAGGAGGTTATAGATAAGTTAAATTCTCTAACTAAAGGAGAAGTTGAAGTAAAGATTCT
TCAAGTGAAGTGAGATAAAA

Downstream 100 bases:

>100_bases
TAATGGACTACGATTAGACGGTAGAAAGCCAGATGAAATGAGACCTATAAAGATAGAATTGGGCGTTTTGAAGAATGCTG
ACGGCTCAGCAATATTCGAA

Product: exosome complex RNA-binding protein Rrp4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSNSKIYFEDRSIVTPGDLIAEGDFQIPWSPYYYKIGNKYYSSITGLIEVKENLFEIVPLEGHRYIPKVGDTVIGLIEDV
EIYGWVLDIKSPYSAYLPASSFLGRPVSPGEDLRRYLNLGDYVIAKIETYDRTINPILSIKGKGLGRVSSGIVIDIPPVK
VPRVIGKNRSMLDTLTSETGCEILVAQNGRILANCATKMIEEALVEAIQIIEKESHIKGLTEKIRKFLREKLGETKNDSA
TKTEANT

Sequences:

>Translated_247_residues
MSNSKIYFEDRSIVTPGDLIAEGDFQIPWSPYYYKIGNKYYSSITGLIEVKENLFEIVPLEGHRYIPKVGDTVIGLIEDV
EIYGWVLDIKSPYSAYLPASSFLGRPVSPGEDLRRYLNLGDYVIAKIETYDRTINPILSIKGKGLGRVSSGIVIDIPPVK
VPRVIGKNRSMLDTLTSETGCEILVAQNGRILANCATKMIEEALVEAIQIIEKESHIKGLTEKIRKFLREKLGETKNDSA
TKTEANT
>Mature_246_residues
SNSKIYFEDRSIVTPGDLIAEGDFQIPWSPYYYKIGNKYYSSITGLIEVKENLFEIVPLEGHRYIPKVGDTVIGLIEDVE
IYGWVLDIKSPYSAYLPASSFLGRPVSPGEDLRRYLNLGDYVIAKIETYDRTINPILSIKGKGLGRVSSGIVIDIPPVKV
PRVIGKNRSMLDTLTSETGCEILVAQNGRILANCATKMIEEALVEAIQIIEKESHIKGLTEKIRKFLREKLGETKNDSAT
KTEANT

Specific function: Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential)

COG id: COG1097

COG function: function code J; RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain

Homologues:

Organism=Saccharomyces cerevisiae, GI6321860, Length=201, Percent_Identity=25.8706467661692, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECR1_SULTO (Q975G7)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376325.1
- ProteinModelPortal:   Q975G7
- SMR:   Q975G7
- GeneID:   1458381
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0444
- NMPDR:   fig|273063.1.peg.493
- HOGENOM:   HBG392276
- OMA:   GQNGRIW
- ProtClustDB:   PRK04163
- BioCyc:   STOK273063:ST0444-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00623
- InterPro:   IPR004087
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00322
- SMART:   SM00316

Pfam domain/function: PF00013 KH_1; PF00575 S1; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 27575; Mature: 27444

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50084 KH_TYPE_1; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSKIYFEDRSIVTPGDLIAEGDFQIPWSPYYYKIGNKYYSSITGLIEVKENLFEIVPL
CCCCEEEEECCCEECCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEECC
EGHRYIPKVGDTVIGLIEDVEIYGWVLDIKSPYSAYLPASSFLGRPVSPGEDLRRYLNLG
CCCEECCCCCHHHHHHHHHHEEEEEEEECCCCCHHHCCCHHHCCCCCCCHHHHHHHHCCC
DYVIAKIETYDRTINPILSIKGKGLGRVSSGIVIDIPPVKVPRVIGKNRSMLDTLTSETG
CEEEEEEEHHCCCCCHHEEECCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHCCCC
CEILVAQNGRILANCATKMIEEALVEAIQIIEKESHIKGLTEKIRKFLREKLGETKNDSA
CEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TKTEANT
CCCCCCC
>Mature Secondary Structure 
SNSKIYFEDRSIVTPGDLIAEGDFQIPWSPYYYKIGNKYYSSITGLIEVKENLFEIVPL
CCCEEEEECCCEECCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEECC
EGHRYIPKVGDTVIGLIEDVEIYGWVLDIKSPYSAYLPASSFLGRPVSPGEDLRRYLNLG
CCCEECCCCCHHHHHHHHHHEEEEEEEECCCCCHHHCCCHHHCCCCCCCHHHHHHHHCCC
DYVIAKIETYDRTINPILSIKGKGLGRVSSGIVIDIPPVKVPRVIGKNRSMLDTLTSETG
CEEEEEEEHHCCCCCHHEEECCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHCCCC
CEILVAQNGRILANCATKMIEEALVEAIQIIEKESHIKGLTEKIRKFLREKLGETKNDSA
CEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TKTEANT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479