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The map label for this gene is 15920543

Identifier: 15920543

GI number: 15920543

Start: 362058

End: 363971

Strand: Reverse

Name: 15920543

Synonym: ST0343

Alternate gene names: NA

Gene position: 363971-362058 (Counterclockwise)

Preceding gene: 15920545

Following gene: 15920538

Centisome position: 13.51

GC content: 34.85

Gene sequence:

>1914_bases
GTGTCGTCTCTTAGATTAAACATAATAGCAACAATATATAATAATATACCAAAAGAGGCTGGAATAACAAAAATTGAGTT
TGAAGGTCCAGAAATAGCAATATATGTTAGGAGTCCAACAATATTGGCTGATAAAACAGATTTGTTAAAGAAAATTGCAA
AGGACATTAGAAAGAGAATTGTGCTGAAAGCTGATGAGAAAGCAAGAAAAGATAAGAAAGAAACAATAGAGATTATAAAG
AATATCGTACCAAAAGAGGCAGAAATTACAGATATAAAGTTTGATGATGAATTAGGTGAAGTACTAATAAAAGCTAAAAA
ACCCGGACTCGTAATAGGTAAAGGAGGAACAATCCAGAATAAAATATTTTTTGAGACTTTTTGGAGACCTATAATAGTAA
GAGAACCACCATTAAAATCAAGAACATATGATAGTATCTTAACACATATTTATAATGAGACTGAATATAGAGCAAAGATG
TTAAAGATCTTTGGTGAAAGAATACATAGAGAACTACTATTCAAAGATAGAAATGTTAGGATAACTGCATTAGGTGGATT
CCAAGAAGTAGGTAGATCTGCAGTACTTGTAGAGACTCCAGAAAGCAAAGTATTATTAGACGTAGGATTAAATCCAAGTG
TAAGTTATGGAGAAAAACTATTTCCAAAGCTTGACATTGATCAAGTAAGACTTGAAGATATTGATGCAGTAGTAATAACG
CATGCACACCTAGACCATTGCGGAATGGTTCCTTTATTATTTAAGTATGGCTATAATGGCCCTGTCTACACAACTGCACC
CACAAGAGATATAATGGCACTAATGCAATTAGATGCACTAGATGTAGCGGAAAAAGAAGGAAGACCCTTGCCCTATACAG
CCAAGGAAGTTAGGAAAGAATTGTTACACACTATAACGCTTGATTATGAAGAAGTTACTGATATAGCTCCAGATATTAAA
CTAACATTCTATAATGCTGGACATATATTAGGCTCTGCTATGGCGCATCTTCATATAGGCGATGGAACACACAATATCGT
TTATACTGGTGATTTCAAATATGCTAGAACTAAATTATTAGATAAGGCTAACGATGAGTTTCCAAGAGTTGATACTATAA
TTATGGAGACAACATATGGAGACCATGAACAAGAAAACAGAGAAGAAGCTGAGGCAAAACTTATAGAGATTATAAATAGA
ACCATTAGTAGGGGAGGAAGAGTACTAATCCCCGTTCTAGCTGTTGGAAGAGGTCAAGAAATAATGCTGGTTTTAAATGA
TGCGATGAAAAAGAAGTTAATACCAGAAGTACCAATCTATGTCACAGGTTTAGTTGAAGAAATTACAGCAATACATAATG
CTTACCCAGAAATGTTAAGCAGAGAAGTAAGGGAAGCAATACTGTATAAGGATGAGAATCCGTTCATGTCGGAATTCTTC
CACAGAATTGAAGGATATAGAGAAGATATTGCGCAAGGCGAGCCATCAATTATCTTAGCAACATCTGGTATGCTAAATGG
AGGCCCGGCAGTAGAATTCTTTAAGACAATGGCTCCAGATAGTAGGAATTCGATAATTTTTGTGAGCTACCAAGCAGAGG
GAACACTGGGTAGAAAAGTGAGTGATGGAGCACAAGAAATACAAATTATTGATAGAGATGGTAGGATTGAGAATATACAA
ATAAAGATGGAAGTCACAAGAGTGGAAGGATTCTCTGGTCACTCTGATAGAAGACAGCTTCTAAACTTCTTAAAGAATCT
AAATGTAAAACCGAAGAATCTATTACTAAATCATGGCGAACCTGGCTCTATAGAATCTTTCAGAAGATTAGTAGAAAGAG
AGAAAGAAAAAATTGGAATGAAAGGGACTAAAGTCTATGCTCCACAGATACTTGATAGCATAAGAGTAGTTTAA

Upstream 100 bases:

>100_bases
TATATGTTCTTTCAGCTCCACAACTTATATAACAAGCATTTATATATTAAAAATTACCATATCTAATTTGTACATCTACT
TCTTATAGTTGGTGAAATAG

Downstream 100 bases:

>100_bases
AACTAGGTAATTCTTAACCTATAATCTTTTAAATCTTAATTTAAAATATGATAATGGGCCCGTCGTCTAGCCTGGTTAGG
ACGCCGCCCTGACGCGGCGG

Product: cleavage and polyadenylation specificity factor large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSSLRLNIIATIYNNIPKEAGITKIEFEGPEIAIYVRSPTILADKTDLLKKIAKDIRKRIVLKADEKARKDKKETIEIIK
NIVPKEAEITDIKFDDELGEVLIKAKKPGLVIGKGGTIQNKIFFETFWRPIIVREPPLKSRTYDSILTHIYNETEYRAKM
LKIFGERIHRELLFKDRNVRITALGGFQEVGRSAVLVETPESKVLLDVGLNPSVSYGEKLFPKLDIDQVRLEDIDAVVIT
HAHLDHCGMVPLLFKYGYNGPVYTTAPTRDIMALMQLDALDVAEKEGRPLPYTAKEVRKELLHTITLDYEEVTDIAPDIK
LTFYNAGHILGSAMAHLHIGDGTHNIVYTGDFKYARTKLLDKANDEFPRVDTIIMETTYGDHEQENREEAEAKLIEIINR
TISRGGRVLIPVLAVGRGQEIMLVLNDAMKKKLIPEVPIYVTGLVEEITAIHNAYPEMLSREVREAILYKDENPFMSEFF
HRIEGYREDIAQGEPSIILATSGMLNGGPAVEFFKTMAPDSRNSIIFVSYQAEGTLGRKVSDGAQEIQIIDRDGRIENIQ
IKMEVTRVEGFSGHSDRRQLLNFLKNLNVKPKNLLLNHGEPGSIESFRRLVEREKEKIGMKGTKVYAPQILDSIRVV

Sequences:

>Translated_637_residues
MSSLRLNIIATIYNNIPKEAGITKIEFEGPEIAIYVRSPTILADKTDLLKKIAKDIRKRIVLKADEKARKDKKETIEIIK
NIVPKEAEITDIKFDDELGEVLIKAKKPGLVIGKGGTIQNKIFFETFWRPIIVREPPLKSRTYDSILTHIYNETEYRAKM
LKIFGERIHRELLFKDRNVRITALGGFQEVGRSAVLVETPESKVLLDVGLNPSVSYGEKLFPKLDIDQVRLEDIDAVVIT
HAHLDHCGMVPLLFKYGYNGPVYTTAPTRDIMALMQLDALDVAEKEGRPLPYTAKEVRKELLHTITLDYEEVTDIAPDIK
LTFYNAGHILGSAMAHLHIGDGTHNIVYTGDFKYARTKLLDKANDEFPRVDTIIMETTYGDHEQENREEAEAKLIEIINR
TISRGGRVLIPVLAVGRGQEIMLVLNDAMKKKLIPEVPIYVTGLVEEITAIHNAYPEMLSREVREAILYKDENPFMSEFF
HRIEGYREDIAQGEPSIILATSGMLNGGPAVEFFKTMAPDSRNSIIFVSYQAEGTLGRKVSDGAQEIQIIDRDGRIENIQ
IKMEVTRVEGFSGHSDRRQLLNFLKNLNVKPKNLLLNHGEPGSIESFRRLVEREKEKIGMKGTKVYAPQILDSIRVV
>Mature_636_residues
SSLRLNIIATIYNNIPKEAGITKIEFEGPEIAIYVRSPTILADKTDLLKKIAKDIRKRIVLKADEKARKDKKETIEIIKN
IVPKEAEITDIKFDDELGEVLIKAKKPGLVIGKGGTIQNKIFFETFWRPIIVREPPLKSRTYDSILTHIYNETEYRAKML
KIFGERIHRELLFKDRNVRITALGGFQEVGRSAVLVETPESKVLLDVGLNPSVSYGEKLFPKLDIDQVRLEDIDAVVITH
AHLDHCGMVPLLFKYGYNGPVYTTAPTRDIMALMQLDALDVAEKEGRPLPYTAKEVRKELLHTITLDYEEVTDIAPDIKL
TFYNAGHILGSAMAHLHIGDGTHNIVYTGDFKYARTKLLDKANDEFPRVDTIIMETTYGDHEQENREEAEAKLIEIINRT
ISRGGRVLIPVLAVGRGQEIMLVLNDAMKKKLIPEVPIYVTGLVEEITAIHNAYPEMLSREVREAILYKDENPFMSEFFH
RIEGYREDIAQGEPSIILATSGMLNGGPAVEFFKTMAPDSRNSIIFVSYQAEGTLGRKVSDGAQEIQIIDRDGRIENIQI
KMEVTRVEGFSGHSDRRQLLNFLKNLNVKPKNLLLNHGEPGSIESFRRLVEREKEKIGMKGTKVYAPQILDSIRVV

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=461, Percent_Identity=31.236442516269, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI33300633, Length=443, Percent_Identity=29.7968397291196, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI34101288, Length=380, Percent_Identity=23.9473684210526, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566029, Length=444, Percent_Identity=31.7567567567568, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32564696, Length=446, Percent_Identity=28.47533632287, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17559452, Length=405, Percent_Identity=22.962962962963, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323307, Length=449, Percent_Identity=28.9532293986637, Blast_Score=178, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24648013, Length=456, Percent_Identity=30.9210526315789, Blast_Score=232, Evalue=7e-61,
Organism=Drosophila melanogaster, GI21358523, Length=445, Percent_Identity=29.6629213483146, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI21358013, Length=388, Percent_Identity=22.680412371134, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650920, Length=289, Percent_Identity=24.5674740484429, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 72143; Mature: 72011

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLRLNIIATIYNNIPKEAGITKIEFEGPEIAIYVRSPTILADKTDLLKKIAKDIRKRI
CCCEEEEEEEEHHHCCCCCCCCEEEEECCCEEEEEEECCEEEECHHHHHHHHHHHHHHHE
VLKADEKARKDKKETIEIIKNIVPKEAEITDIKFDDELGEVLIKAKKPGLVIGKGGTIQN
EECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHEEECCCCEEEECCCCCCH
KIFFETFWRPIIVREPPLKSRTYDSILTHIYNETEYRAKMLKIFGERIHRELLFKDRNVR
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
ITALGGFQEVGRSAVLVETPESKVLLDVGLNPSVSYGEKLFPKLDIDQVRLEDIDAVVIT
EEEECCHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCCEECCCCCEEEEE
HAHLDHCGMVPLLFKYGYNGPVYTTAPTRDIMALMQLDALDVAEKEGRPLPYTAKEVRKE
ECCCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LLHTITLDYEEVTDIAPDIKLTFYNAGHILGSAMAHLHIGDGTHNIVYTGDFKYARTKLL
HHHHHCCCHHHHHHCCCCEEEEEEECCHHHHHHHEEEEECCCCCEEEEECCCHHHHHHHH
DKANDEFPRVDTIIMETTYGDHEQENREEAEAKLIEIINRTISRGGRVLIPVLAVGRGQE
HCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCE
IMLVLNDAMKKKLIPEVPIYVTGLVEEITAIHNAYPEMLSREVREAILYKDENPFMSEFF
EEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HRIEGYREDIAQGEPSIILATSGMLNGGPAVEFFKTMAPDSRNSIIFVSYQAEGTLGRKV
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
SDGAQEIQIIDRDGRIENIQIKMEVTRVEGFSGHSDRRQLLNFLKNLNVKPKNLLLNHGE
CCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHEEEECCC
PGSIESFRRLVEREKEKIGMKGTKVYAPQILDSIRVV
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC
>Mature Secondary Structure 
SSLRLNIIATIYNNIPKEAGITKIEFEGPEIAIYVRSPTILADKTDLLKKIAKDIRKRI
CCEEEEEEEEHHHCCCCCCCCEEEEECCCEEEEEEECCEEEECHHHHHHHHHHHHHHHE
VLKADEKARKDKKETIEIIKNIVPKEAEITDIKFDDELGEVLIKAKKPGLVIGKGGTIQN
EECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHEEECCCCEEEECCCCCCH
KIFFETFWRPIIVREPPLKSRTYDSILTHIYNETEYRAKMLKIFGERIHRELLFKDRNVR
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
ITALGGFQEVGRSAVLVETPESKVLLDVGLNPSVSYGEKLFPKLDIDQVRLEDIDAVVIT
EEEECCHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCCEECCCCCEEEEE
HAHLDHCGMVPLLFKYGYNGPVYTTAPTRDIMALMQLDALDVAEKEGRPLPYTAKEVRKE
ECCCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LLHTITLDYEEVTDIAPDIKLTFYNAGHILGSAMAHLHIGDGTHNIVYTGDFKYARTKLL
HHHHHCCCHHHHHHCCCCEEEEEEECCHHHHHHHEEEEECCCCCEEEEECCCHHHHHHHH
DKANDEFPRVDTIIMETTYGDHEQENREEAEAKLIEIINRTISRGGRVLIPVLAVGRGQE
HCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCE
IMLVLNDAMKKKLIPEVPIYVTGLVEEITAIHNAYPEMLSREVREAILYKDENPFMSEFF
EEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HRIEGYREDIAQGEPSIILATSGMLNGGPAVEFFKTMAPDSRNSIIFVSYQAEGTLGRKV
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
SDGAQEIQIIDRDGRIENIQIKMEVTRVEGFSGHSDRRQLLNFLKNLNVKPKNLLLNHGE
CCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHEEEECCC
PGSIESFRRLVEREKEKIGMKGTKVYAPQILDSIRVV
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]