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The map label for this gene is 15920399

Identifier: 15920399

GI number: 15920399

Start: 239878

End: 240513

Strand: Direct

Name: 15920399

Synonym: ST0218

Alternate gene names: NA

Gene position: 239878-240513 (Clockwise)

Preceding gene: 15920398

Following gene: 15920401

Centisome position: 8.9

GC content: 27.83

Gene sequence:

>636_bases
ATGAAGGTATTATTCCTTAGGCCCGAAGGATCTAATATTCCTTATAATAAGAATTTTATTGAAATTAGTATTTTAAAACC
TGAATGTATAAATTATACTGTTAATTTACACGAGATAGACGGCCTTGGATTCACGAGTATTAATGCAGTAAGATGTTTTA
AAGACTTTGATAAAATTGAAGGAAAAGCTATATTTGCCGTAGGACCTAGTACATCGGAAGAGCTAATTAAGCGTAATATT
AAAAATGTGATTATACCAGAAGAATATACTGTAGAAAATCTGGTAAAACTAATAAAGCAGAATACTAAAAATCCACTTCT
AGTTAGGAGTTTGATAGCAATAGATAACAGTTTAGATATCAAGCAAATTGCTGATTATAATTTAAAAGCAGATTTACAAA
AACTAGAAGAAGCCAGAGAGTTAATTGAAAAATGTAAAGTTAATATAATAGTTTTAACTAGCTCTTATATAGCTAGTTTA
GTGAAAGATTTTATAAAAGAATGTGAAATAATAGTAAGCATAGGTCCGTCTACTTCTAAAGTAATTAAAGATAAGAAAAA
CATATATGAAGCGAAAGAGCATGATATGAAAGGAATTTTAAAATTATTAAAAGAATTGGGTGCTTATGATGGATGA

Upstream 100 bases:

>100_bases
TTTGGTAGGAAAAAGATTACAATAGAAGAGTATTTTCATAACATGACTCCTTATGAAGCAGGGGAATTATTAGGTAAAAG
ATTCTTGGAGGAAATAAAAA

Downstream 100 bases:

>100_bases
AGAAATAAAATCAATAACAATTTCTACATTAAAGAAATTGATTGGAGATTTTGATATAAATACACTGGAGATAAAGTTTT
ATCAGTCATTTAAGGATAGA

Product: hypothetical protein

Products: uroporphyrinogen III; H2O

Alternate protein names: None

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKVLFLRPEGSNIPYNKNFIEISILKPECINYTVNLHEIDGLGFTSINAVRCFKDFDKIEGKAIFAVGPSTSEELIKRNI
KNVIIPEEYTVENLVKLIKQNTKNPLLVRSLIAIDNSLDIKQIADYNLKADLQKLEEARELIEKCKVNIIVLTSSYIASL
VKDFIKECEIIVSIGPSTSKVIKDKKNIYEAKEHDMKGILKLLKELGAYDG

Sequences:

>Translated_211_residues
MKVLFLRPEGSNIPYNKNFIEISILKPECINYTVNLHEIDGLGFTSINAVRCFKDFDKIEGKAIFAVGPSTSEELIKRNI
KNVIIPEEYTVENLVKLIKQNTKNPLLVRSLIAIDNSLDIKQIADYNLKADLQKLEEARELIEKCKVNIIVLTSSYIASL
VKDFIKECEIIVSIGPSTSKVIKDKKNIYEAKEHDMKGILKLLKELGAYDG
>Mature_211_residues
MKVLFLRPEGSNIPYNKNFIEISILKPECINYTVNLHEIDGLGFTSINAVRCFKDFDKIEGKAIFAVGPSTSEELIKRNI
KNVIIPEEYTVENLVKLIKQNTKNPLLVRSLIAIDNSLDIKQIADYNLKADLQKLEEARELIEKCKVNIIVLTSSYIASL
VKDFIKECEIIVSIGPSTSKVIKDKKNIYEAKEHDMKGILKLLKELGAYDG

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23872; Mature: 23872

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLFLRPEGSNIPYNKNFIEISILKPECINYTVNLHEIDGLGFTSINAVRCFKDFDKIE
CEEEEECCCCCCCCCCCCEEEEEEECCHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
GKAIFAVGPSTSEELIKRNIKNVIIPEEYTVENLVKLIKQNTKNPLLVRSLIAIDNSLDI
CCEEEEECCCCHHHHHHHHHHCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
KQIADYNLKADLQKLEEARELIEKCKVNIIVLTSSYIASLVKDFIKECEIIVSIGPSTSK
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCEEEEEECCCHHH
VIKDKKNIYEAKEHDMKGILKLLKELGAYDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVLFLRPEGSNIPYNKNFIEISILKPECINYTVNLHEIDGLGFTSINAVRCFKDFDKIE
CEEEEECCCCCCCCCCCCEEEEEEECCHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHCC
GKAIFAVGPSTSEELIKRNIKNVIIPEEYTVENLVKLIKQNTKNPLLVRSLIAIDNSLDI
CCEEEEECCCCHHHHHHHHHHCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
KQIADYNLKADLQKLEEARELIEKCKVNIIVLTSSYIASLVKDFIKECEIIVSIGPSTSK
HHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCEEEEEECCCHHH
VIKDKKNIYEAKEHDMKGILKLLKELGAYDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA