BacMap

Definition	Sulfolobus tokodaii str. 7 chromosome, complete genome.
Accession	NC_003106
Length	2,694,756

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The map label for this gene is yeaE [H]

Identifier: 15920307

GI number: 15920307

Start: 150728

End: 151531

Strand: Direct

Name: yeaE [H]

Synonym: ST0130

Alternate gene names: 15920307

Gene position: 150728-151531 (Clockwise)

Preceding gene: 15920305

Following gene: 15920313

Centisome position: 5.59

GC content: 31.22

Gene sequence:

>804_bases
ATGAAAAAGTTCAAATGGTTCTCAATTTCTCCATTAGCATTAGGAACTTGGGGAATGGGAGGAGGTTATTGGTCAACAGA
TTATTCAAATGATGAAAATGATATAAAAGCGATTATAAAAGCAATAGAACTTGGAATTACAGCAATAGATACTGCCGAAA
TGTATGGAAATGGACATGCGGAAGAACTTGTTGGAAAAGCTATTAAGAATTTTAAGAGAGAAGAACTTTTTATTATTACA
AAAGTCTGGCCTAATCATGCTAAATATGAGGATGTTTTAAAATCCGCAATTGCGAGTTCAAAAAGACTTGGTACTTATAT
TGATCTTTACTTTTTACATTGGCCCTCAAATGTACCAATATGTGAAACTATTAAAGCCTTTGAAGACCTAGTTGATAAAG
GAGTAATTAGATATTTTGGATTAAGCAACTTCAAATGGAGAGAAATTGAGAAAGCTTCTGAATGTGTTAAAAAATACGAG
ATAGCTGCAGTAGAAAACCATTATAGTTTATGGGATAGAGGAGACGAAGAAACTTTAGAATATGCTAACAAAAAAGGATT
ACTTTACTTAGCATATACACCTATTGAGAAAGGAAGAATAAAAAATGATAAATTCCTTTCTGAAATAGCAAAGAAATATA
ACAAAACTCCTATACAAATTGCTCTAAATTGGTACATTAGAATTCCTAGTTTAGTACCTATAGTTAAGAGTAGCAATATT
TCGCATTTAGAAGAGAATGTAGGAGCATTAGGATGGGAATTAAGTGAGGAAGATTGGAAAAAGATAAATGAGCATTTCAA
ATAA

Upstream 100 bases:

>100_bases
TTTTTCTGCTTAGATTCATCCCAGCTTATTTAATTTACGAAGTTCCACAAGAGAAGACCCAGGCATGCCCTTATTAACTT
AAAAGATAAAAAAATGTGGT

Downstream 100 bases:

>100_bases
GAACTCTTTTCTTTTTTCTATTTCTGTATATGTACAGAGTTAAACGGACAAATTTAAATTATAATGATAAACATTAAATA
AAATAATAAAAATTATTACT

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKKFKWFSISPLALGTWGMGGGYWSTDYSNDENDIKAIIKAIELGITAIDTAEMYGNGHAEELVGKAIKNFKREELFIIT
KVWPNHAKYEDVLKSAIASSKRLGTYIDLYFLHWPSNVPICETIKAFEDLVDKGVIRYFGLSNFKWREIEKASECVKKYE
IAAVENHYSLWDRGDEETLEYANKKGLLYLAYTPIEKGRIKNDKFLSEIAKKYNKTPIQIALNWYIRIPSLVPIVKSSNI
SHLEENVGALGWELSEEDWKKINEHFK

Sequences:

>Translated_267_residues
MKKFKWFSISPLALGTWGMGGGYWSTDYSNDENDIKAIIKAIELGITAIDTAEMYGNGHAEELVGKAIKNFKREELFIIT
KVWPNHAKYEDVLKSAIASSKRLGTYIDLYFLHWPSNVPICETIKAFEDLVDKGVIRYFGLSNFKWREIEKASECVKKYE
IAAVENHYSLWDRGDEETLEYANKKGLLYLAYTPIEKGRIKNDKFLSEIAKKYNKTPIQIALNWYIRIPSLVPIVKSSNI
SHLEENVGALGWELSEEDWKKINEHFK
>Mature_267_residues
MKKFKWFSISPLALGTWGMGGGYWSTDYSNDENDIKAIIKAIELGITAIDTAEMYGNGHAEELVGKAIKNFKREELFIIT
KVWPNHAKYEDVLKSAIASSKRLGTYIDLYFLHWPSNVPICETIKAFEDLVDKGVIRYFGLSNFKWREIEKASECVKKYE
IAAVENHYSLWDRGDEETLEYANKKGLLYLAYTPIEKGRIKNDKFLSEIAKKYNKTPIQIALNWYIRIPSLVPIVKSSNI
SHLEENVGALGWELSEEDWKKINEHFK

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24497577, Length=294, Percent_Identity=29.5918367346939, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI5174391, Length=294, Percent_Identity=29.5918367346939, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI223468663, Length=284, Percent_Identity=29.2253521126761, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI310109922, Length=266, Percent_Identity=29.3233082706767, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI291291012, Length=267, Percent_Identity=29.2134831460674, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI5453543, Length=286, Percent_Identity=27.972027972028, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI45446745, Length=286, Percent_Identity=27.972027972028, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4503285, Length=286, Percent_Identity=27.972027972028, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310109920, Length=286, Percent_Identity=27.972027972028, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI24497583, Length=265, Percent_Identity=29.0566037735849, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI24497585, Length=286, Percent_Identity=26.5734265734266, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=29.2096219931272, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI27436969, Length=296, Percent_Identity=26.3513513513513, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4504825, Length=296, Percent_Identity=26.3513513513513, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27436966, Length=296, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436962, Length=296, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436964, Length=296, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5174695, Length=290, Percent_Identity=26.551724137931, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI300116273, Length=274, Percent_Identity=26.2773722627737, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1788081, Length=267, Percent_Identity=32.5842696629214, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786400, Length=262, Percent_Identity=32.4427480916031, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87081735, Length=310, Percent_Identity=27.4193548387097, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.7955271565495, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082198, Length=255, Percent_Identity=32.9411764705882, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787674, Length=249, Percent_Identity=26.1044176706827, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789375, Length=318, Percent_Identity=26.1006289308176, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI48994888, Length=278, Percent_Identity=26.978417266187, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=32.2097378277154, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17537077, Length=296, Percent_Identity=28.3783783783784, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537075, Length=296, Percent_Identity=28.3783783783784, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17566692, Length=294, Percent_Identity=28.2312925170068, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538386, Length=278, Percent_Identity=25.8992805755396, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17550248, Length=287, Percent_Identity=26.4808362369338, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561300, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17537079, Length=266, Percent_Identity=25.187969924812, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=270, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322556, Length=271, Percent_Identity=28.0442804428044, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324694, Length=294, Percent_Identity=29.5918367346939, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320576, Length=292, Percent_Identity=28.4246575342466, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=324, Percent_Identity=25.3086419753086, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI20129731, Length=281, Percent_Identity=30.2491103202847, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24657054, Length=278, Percent_Identity=28.7769784172662, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45553081, Length=280, Percent_Identity=29.2857142857143, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24663317, Length=270, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281366140, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644950, Length=293, Percent_Identity=28.3276450511945, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356425, Length=288, Percent_Identity=26.0416666666667, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646155, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24662781, Length=283, Percent_Identity=28.6219081272085, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30800; Mature: 30800

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFKWFSISPLALGTWGMGGGYWSTDYSNDENDIKAIIKAIELGITAIDTAEMYGNGHA
CCCCCEEECCCCEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHCCCCH
EELVGKAIKNFKREELFIITKVWPNHAKYEDVLKSAIASSKRLGTYIDLYFLHWPSNVPI
HHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
CETIKAFEDLVDKGVIRYFGLSNFKWREIEKASECVKKYEIAAVENHYSLWDRGDEETLE
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHH
YANKKGLLYLAYTPIEKGRIKNDKFLSEIAKKYNKTPIQIALNWYIRIPSLVPIVKSSNI
HHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHCCCCH
SHLEENVGALGWELSEEDWKKINEHFK
HHHHHHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKKFKWFSISPLALGTWGMGGGYWSTDYSNDENDIKAIIKAIELGITAIDTAEMYGNGHA
CCCCCEEECCCCEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHCCCCH
EELVGKAIKNFKREELFIITKVWPNHAKYEDVLKSAIASSKRLGTYIDLYFLHWPSNVPI
HHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
CETIKAFEDLVDKGVIRYFGLSNFKWREIEKASECVKKYEIAAVENHYSLWDRGDEETLE
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHH
YANKKGLLYLAYTPIEKGRIKNDKFLSEIAKKYNKTPIQIALNWYIRIPSLVPIVKSSNI
HHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHCCCCH
SHLEENVGALGWELSEEDWKKINEHFK
HHHHHHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]