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The map label for this gene is secY [H]

Identifier: 159041819

GI number: 159041819

Start: 1324814

End: 1326262

Strand: Reverse

Name: secY [H]

Synonym: Cmaq_1254

Alternate gene names: 159041819

Gene position: 1326262-1324814 (Counterclockwise)

Preceding gene: 159041820

Following gene: 159041817

Centisome position: 63.84

GC content: 45.07

Gene sequence:

>1449_bases
GTGGCGTCTAAGCGATTCATAGAGATGGTGGAACCGCTCTTAACGCTAATGCCCACTGTCCCCAGGCCCAATAGGCCGGT
TACCCTGGGTAGTAGGCTAATATGGACCTTCCTAGCGGCTACAGTTTACCTACTCCTATCAGTAACGCCGCTATACGGTA
TTGTGGCTTCATCAAGTAGCCCGCTCTTCAACCCGCTGGTGGCTATAATATTCGCCTCAACCAACGGTACATTGGCTCAA
CTGGGTATAGGCCCAATAATAATAGCTGGAATAATAATGGAGCTTGTAGCCTTCTCTGAGTTAATGGATGTTGACTTAAA
TGACCCTAAGGATCAAGCAAGGTTCACTGCATTAACGAAGCTTGTAGCCGTGATAATAGCCATGTTTGAGGGAGCATTCA
TAATGTCAACCCACCAGTTAACCGTAGCCAACGCTGGATTAGCCTTCATTGTGTGGCTTCAAATGTTGTTCGGAGCCGTA
ATAGTTATACTGCTTGATGACTTAATATCCAAGGGATGGGGTATTGGAAGCGGCATATCATTATTCATACTCATAAGCAT
AATTAGGTCCATTTTCCAATCCACATTCATGCCTGTAACCGTGGGTGCAGGGGAGTTACTAGGTATTATACCTGCCCTAG
TGGCTGCAGTATACAGCGCCGCAGTATCCCACACGCTTGCACCATTATTATCCATAGTTTATAGATTCAACCTACCCGGC
CTAATAGGCTTAATCGCAACAATAGTCCTAGGTGGCTTCATAGCATACGTTGAGTTAATGGAGGTTAGGATACCGTTATC
CTTCGTGCAGTACGGTGGATACAAGATGTCGTACCCATTCAAGGTAATGTACGTCTCAGTCCTACCCATAATATTCACAG
CATACACAGTGGCGTTAATATATAATGGACTCTACTTCATTTGGACAACATATAATCCCCATAACGCTAACGCATTATTA
AATTCAATAGCCTGCATAAGGGTTATTACAACCGCTAAATTCGGTACTATTAATGAACCATGTCCATCATCCTTAATATA
CTACTTCACCGTGGTGCCGTATAACATTACCCCACAGTACGTGGTGGTTCACATACTCATGTACGTCGTGCTCTCAGTGG
TCTTCGCCTACCTATGGGTTAATTTAGCTGGTTTAAGCGCCGAGGATCAGGCCAGGACCATGGTTTCAAGCGGCTTATCA
ATACCAGGCTTCAGGGCATCAGCGAGGTCGCTTGCAGTGCACTTGAAGAGGTACGTTAATTCACTAACCTTCACCAGCGG
CTTACTGGCTGGTTTCATTGCAGCCCTTGGTGATGTATTAGGTGTATATGGTACTGGCATAGGCCTAATACTAATGGTGG
AGATAATAATACAGTACTACACGATAGCGATGCAGGAGCAGTTGTTTGAGGCTTATCCAGGGCTTAAGAGGATTCTAGGT
GTTGAGTAA

Upstream 100 bases:

>100_bases
ATGATTTAGAGCGCACTAGGGTTACATTACGTGTGCTAATCAGTTATTGACGCAATGACTGCTAATAAACCTTATTAATC
CCAGTAATTTTAGGTGAACT

Downstream 100 bases:

>100_bases
GGATTAATATTTCACTCAGCATCATGCCTCCTCATGCTTAGCCTCTTCTTAAGCTCCCTTAAACATGTTTTACAACATAG
GTAATACACCCTCCTCCCCC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: Protein transport protein SEC61 subunit alpha homolog [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MASKRFIEMVEPLLTLMPTVPRPNRPVTLGSRLIWTFLAATVYLLLSVTPLYGIVASSSSPLFNPLVAIIFASTNGTLAQ
LGIGPIIIAGIIMELVAFSELMDVDLNDPKDQARFTALTKLVAVIIAMFEGAFIMSTHQLTVANAGLAFIVWLQMLFGAV
IVILLDDLISKGWGIGSGISLFILISIIRSIFQSTFMPVTVGAGELLGIIPALVAAVYSAAVSHTLAPLLSIVYRFNLPG
LIGLIATIVLGGFIAYVELMEVRIPLSFVQYGGYKMSYPFKVMYVSVLPIIFTAYTVALIYNGLYFIWTTYNPHNANALL
NSIACIRVITTAKFGTINEPCPSSLIYYFTVVPYNITPQYVVVHILMYVVLSVVFAYLWVNLAGLSAEDQARTMVSSGLS
IPGFRASARSLAVHLKRYVNSLTFTSGLLAGFIAALGDVLGVYGTGIGLILMVEIIIQYYTIAMQEQLFEAYPGLKRILG
VE

Sequences:

>Translated_482_residues
MASKRFIEMVEPLLTLMPTVPRPNRPVTLGSRLIWTFLAATVYLLLSVTPLYGIVASSSSPLFNPLVAIIFASTNGTLAQ
LGIGPIIIAGIIMELVAFSELMDVDLNDPKDQARFTALTKLVAVIIAMFEGAFIMSTHQLTVANAGLAFIVWLQMLFGAV
IVILLDDLISKGWGIGSGISLFILISIIRSIFQSTFMPVTVGAGELLGIIPALVAAVYSAAVSHTLAPLLSIVYRFNLPG
LIGLIATIVLGGFIAYVELMEVRIPLSFVQYGGYKMSYPFKVMYVSVLPIIFTAYTVALIYNGLYFIWTTYNPHNANALL
NSIACIRVITTAKFGTINEPCPSSLIYYFTVVPYNITPQYVVVHILMYVVLSVVFAYLWVNLAGLSAEDQARTMVSSGLS
IPGFRASARSLAVHLKRYVNSLTFTSGLLAGFIAALGDVLGVYGTGIGLILMVEIIIQYYTIAMQEQLFEAYPGLKRILG
VE
>Mature_481_residues
ASKRFIEMVEPLLTLMPTVPRPNRPVTLGSRLIWTFLAATVYLLLSVTPLYGIVASSSSPLFNPLVAIIFASTNGTLAQL
GIGPIIIAGIIMELVAFSELMDVDLNDPKDQARFTALTKLVAVIIAMFEGAFIMSTHQLTVANAGLAFIVWLQMLFGAVI
VILLDDLISKGWGIGSGISLFILISIIRSIFQSTFMPVTVGAGELLGIIPALVAAVYSAAVSHTLAPLLSIVYRFNLPGL
IGLIATIVLGGFIAYVELMEVRIPLSFVQYGGYKMSYPFKVMYVSVLPIIFTAYTVALIYNGLYFIWTTYNPHNANALLN
SIACIRVITTAKFGTINEPCPSSLIYYFTVVPYNITPQYVVVHILMYVVLSVVFAYLWVNLAGLSAEDQARTMVSSGLSI
PGFRASARSLAVHLKRYVNSLTFTSGLLAGFIAALGDVLGVYGTGIGLILMVEIIIQYYTIAMQEQLFEAYPGLKRILGV
E

Specific function: Involved in protein export. Interacts with secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Homo sapiens, GI7019415, Length=472, Percent_Identity=31.3559322033898, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI14589847, Length=475, Percent_Identity=31.5789473684211, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI217330618, Length=475, Percent_Identity=30.9473684210526, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI217330616, Length=431, Percent_Identity=30.1624129930394, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17543770, Length=475, Percent_Identity=30.9473684210526, Blast_Score=203, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323411, Length=475, Percent_Identity=28.6315789473684, Blast_Score=182, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6319760, Length=504, Percent_Identity=23.2142857142857, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920826, Length=473, Percent_Identity=30.4439746300211, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201
- InterPro:   IPR019561 [H]

Pfam domain/function: PF10559 Plug_translocon; PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 52349; Mature: 52218

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKRFIEMVEPLLTLMPTVPRPNRPVTLGSRLIWTFLAATVYLLLSVTPLYGIVASSSS
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLFNPLVAIIFASTNGTLAQLGIGPIIIAGIIMELVAFSELMDVDLNDPKDQARFTALTK
CHHHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LVAVIIAMFEGAFIMSTHQLTVANAGLAFIVWLQMLFGAVIVILLDDLISKGWGIGSGIS
HHHHHHHHHCCCCEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LFILISIIRSIFQSTFMPVTVGAGELLGIIPALVAAVYSAAVSHTLAPLLSIVYRFNLPG
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LIGLIATIVLGGFIAYVELMEVRIPLSFVQYGGYKMSYPFKVMYVSVLPIIFTAYTVALI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHH
YNGLYFIWTTYNPHNANALLNSIACIRVITTAKFGTINEPCPSSLIYYFTVVPYNITPQY
HCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHH
VVVHILMYVVLSVVFAYLWVNLAGLSAEDQARTMVSSGLSIPGFRASARSLAVHLKRYVN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SLTFTSGLLAGFIAALGDVLGVYGTGIGLILMVEIIIQYYTIAMQEQLFEAYPGLKRILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
VE
CC
>Mature Secondary Structure 
ASKRFIEMVEPLLTLMPTVPRPNRPVTLGSRLIWTFLAATVYLLLSVTPLYGIVASSSS
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLFNPLVAIIFASTNGTLAQLGIGPIIIAGIIMELVAFSELMDVDLNDPKDQARFTALTK
CHHHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LVAVIIAMFEGAFIMSTHQLTVANAGLAFIVWLQMLFGAVIVILLDDLISKGWGIGSGIS
HHHHHHHHHCCCCEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LFILISIIRSIFQSTFMPVTVGAGELLGIIPALVAAVYSAAVSHTLAPLLSIVYRFNLPG
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LIGLIATIVLGGFIAYVELMEVRIPLSFVQYGGYKMSYPFKVMYVSVLPIIFTAYTVALI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHH
YNGLYFIWTTYNPHNANALLNSIACIRVITTAKFGTINEPCPSSLIYYFTVVPYNITPQY
HCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHH
VVVHILMYVVLSVVFAYLWVNLAGLSAEDQARTMVSSGLSIPGFRASARSLAVHLKRYVN
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SLTFTSGLLAGFIAALGDVLGVYGTGIGLILMVEIIIQYYTIAMQEQLFEAYPGLKRILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
VE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]